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- Author:
- Hayes, Rachel L.; Garnett, Sarah P.; Clarke, Samantha L.; Harkin, Nuala M.; Chan, Albert K.F.; Ambler, Geoffrey R.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 705-709
- ISSN:
- 0261-5614
- Subject:
- adolescents; body mass index; diet; glycemic control; hemoglobin; insulin; insulin-dependent diabetes mellitus; quality of life; questionnaires
- Abstract:
- ... BACKGROUND & AIMS: There is significant interest in the utility of flexible meal plans for individuals with type 1 diabetes. However, there is a paucity of data examining this approach in adolescents. The aim of this study was to assess glycemic control, weight status and quality of life over 12 months in adolescents with type 1 diabetes, who were commenced on a flexible meal plan using an insulin ...
- DOI:
- 10.1016/j.clnu.2012.02.012
- PubMed:
- 22464678
-
http://dx.doi.org/10.1016/j.clnu.2012.02.012
- Author:
- Hojsak, Iva; Strizić, Helena; Mišak, Zrinjka; Rimac, Irena; Bukovina, Gordana; Prlić, Hrvoje; Kolaček, Sanja
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 672-675
- ISSN:
- 0261-5614
- Subject:
- catheters; children; parenteral feeding; patients; septic shock
- Abstract:
- ... BACKGROUND & AIMS: The aim was to assess the rate of central venous catheter (CVC) related sepsis in patients on parenteral nutrition (PN) at our hospital center during a period of 21 years. METHODS: Data on all children hospitalized at our tertiary hospital center during the 1989-2010 period, who received PN for more than 4 weeks (n = 62) were retrospectively analyzed. RESULTS: The mean age at th ...
- DOI:
- 10.1016/j.clnu.2012.02.006
- PubMed:
- 22402421
-
http://dx.doi.org/10.1016/j.clnu.2012.02.006
- Author:
- Akilen, Rajadurai; Tsiami, Amalia; Devendra, Devasenan; Robinson, Nicola
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 609-615
- ISSN:
- 0261-5614
- Subject:
- Cinnamomum aromaticum; Cinnamomum verum; adipocytes; cinnamon; clinical trials; glucose; glycemic control; glycemic effect; insulin; meta-analysis; noninsulin-dependent diabetes mellitus; patients; skeletal muscle; systematic review
- Abstract:
- ... BACKGROUND & AIMS: Cinnamon seems to be highly bioactive, appearing to mimic the effect of insulin through increased glucose uptake in adipocytes and skeletal muscles. This systematic review and Meta analysis examined the effect of cinnamon on glycaemic control in patients with Type 2 Diabetes mellitus. METHODS: A systematic literature search was conducted from the earliest possible date through t ...
- DOI:
- 10.1016/j.clnu.2012.04.003
-
http://dx.doi.org/10.1016/j.clnu.2012.04.003
- Author:
- Bassaganya-Riera, Josep; Hontecillas, Raquel; Horne, William T.; Sandridge, Mikki; Herfarth, Hans H.; Bloomfeld, Richard; Isaacs, Kim L.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 721-727
- ISSN:
- 0261-5614
- Subject:
- CD8-positive T-lymphocytes; Crohn disease; colitis; conjugated linoleic acid; immune response; immunomodulators; interferon-gamma; mice; models; patients; quality of life; questionnaires; swine; tumor necrosis factor-alpha
- Abstract:
- ... BACKGROUND & AIMS: Conjugated linoleic acid (CLA) has demonstrated efficacy as an immune modulator and anti-inflammatory compound in mouse and pig models of colitis. We investigated the immunoregulatory efficacy of CLA in patients with mild to moderate Crohn's disease (CD). METHODS: Thirteen patients with mild to moderately active CD were enrolled in an open-label study of CLA (6 g/d orally) for 1 ...
- DOI:
- 10.1016/j.clnu.2012.03.002
- PubMed:
- 22521469
-
http://dx.doi.org/10.1016/j.clnu.2012.03.002
- Author:
- Caporali, Roberto; Caccialanza, Riccardo; Bonino, Claudia; Klersy, Catherine; Cereda, Emanuele; Xoxi, Blerina; Crippa, Anna; Rava, Maria Luisa; Orlandi, Margherita; Bonardi, Chiara; Cameletti, Barbara; Codullo, Veronica; Montecucco, Carlomaurizio
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 666-671
- ISSN:
- 0261-5614
- Subject:
- blood serum; body mass index; functional status; gastrointestinal system; malnutrition; nutrition assessment; patients; prealbumin; prospective studies; regression analysis; sclerosis; weight loss
- Abstract:
- ... BACKGROUND & AIM: Disease-related malnutrition is known to negatively affect clinical outcomes. The aim of the present study was to evaluate the prevalence of malnutrition in a cohort of outpatients affected by Systemic Sclerosis (SSc) and its association with clinical variables. METHODS: One hundred sixty SSc patients were consecutively evaluated. The following clinical variables were assessed: d ...
- DOI:
- 10.1016/j.clnu.2012.02.010
- PubMed:
- 22417677
-
http://dx.doi.org/10.1016/j.clnu.2012.02.010
- Author:
- Chougala, Mallikarjun B.; Bhaskar, Jamuna J.; Rajan, M.G.R.; Salimath, Paramahans V.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 749-755
- ISSN:
- 0261-5614
- Subject:
- acid phosphatase; beta-N-acetylhexosaminidase; beta-galactosidase; brain; curcumin; diabetes; diet; enzyme activity; liver; quercetin; rats; spleen; testes
- Abstract:
- ... BACKGROUND & AIMS: Diabetes causes impairment of various enzyme activities in the physiological system, including lysosomal enzymes. The effect of feeding curcumin, quercetin and aminoguanidine on lysosomal enzyme activities viz., N-acetyl-β-d-glucosaminidase, β-d-glucuronidase, β-d-galactosidase and acid phosphatase were studied in different tissues of streptozotocin-induced diabetic rats. METHOD ...
- DOI:
- 10.1016/j.clnu.2012.02.003
- PubMed:
- 22445558
-
http://dx.doi.org/10.1016/j.clnu.2012.02.003
- Author:
- Engelen, M.P.K.J.; De Castro, C.L.N.; Rutten, E.P.A.; Wouters, E.F.M.; Schols, A.M.W.J.; Deutz, N.E.P.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 616-624
- ISSN:
- 0261-5614
- Subject:
- body protein; elderly; intravenous injection; isoleucine; leucine; metabolism; milk proteins; patients; phenylalanine; stable isotopes; valine; whey protein
- Abstract:
- ... BACKGROUND & AIMS: We previously observed in elderly subjects with Chronic Obstructive Pulmonary Disease (COPD) an enhanced anabolic response to milk protein sip feeding, associated with reduced splanchnic extraction (SPE) of phenylalanine. Milk proteins are known for their high Branched-chain Amino Acids (BCAA) content, but no information is present about splanchnic extraction and metabolism of t ...
- DOI:
- 10.1016/j.clnu.2012.04.006
- PubMed:
- 22682082
- PubMed Central:
- PMC3440534
-
http://dx.doi.org/10.1016/j.clnu.2012.04.006
- Author:
- Yang, Chih-Yu; Wu, Ming-Ling; Chou, Yea-Yun; Li, Szu-Yuan; Deng, Jou-Fang; Yang, Wu-Chang; Ng, Yee-Yung
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 630-636
- ISSN:
- 0261-5614
- Subject:
- blood serum; cohort studies; copper; death; diabetes mellitus; dialysis; infectious diseases; mortality; oxidation; patients; regression analysis; risk factors; selenium; stroke; trace element deficiencies; zinc
- Abstract:
- ... BACKGROUND & AIMS: Essential trace elements are involved in many biological processes for normal cell function including immunological defense against oxidation and infection. Deficiency of these elements generally leads to illness or even death in the general population. Therefore, we investigated the predictive values of trace element status on clinical outcomes in dialysis patients, who are mor ...
- DOI:
- 10.1016/j.clnu.2012.02.008
- PubMed:
- 22405403
-
http://dx.doi.org/10.1016/j.clnu.2012.02.008
- Author:
- Sorensen, Janice; Holm, Lotte; Frøst, Michael Bom; Kondrup, Jens
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 637-646
- ISSN:
- 0261-5614
- Subject:
- food choices; food intake; food quality; food records; foods; gastrointestinal system; hospital diet; hunger; interviews; medicine; models; motivation; odors; patients; risk; surgery; taste; temperature; texture
- Abstract:
- ... BACKGROUND & AIMS: The aim was to investigate food sensory quality as experienced and perceived by patients at nutritional risk within the context of establishing a framework to develop foods to develop foods to promote intake. METHODS: Patients at nutritional risk (NRS-2002; food intake ≤75% of requirements) were observed at meals in hospital (food choice, hunger/fullness/appetite scores). This w ...
- DOI:
- 10.1016/j.clnu.2012.01.004
- PubMed:
- 22365612
-
http://dx.doi.org/10.1016/j.clnu.2012.01.004
- Author:
- Bronhara, Bruna; Piccoli, Antonio; Pereira, Júlio César R.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 710-716
- ISSN:
- 0261-5614
- Subject:
- bioelectrical impedance; body composition; databases; models; uncertainty
- Abstract:
- ... BACKGROUNDS & AIMS: The boundaries between the categories of body composition provided by vectorial analysis of bioimpedance are not well defined. In this paper, fuzzy sets theory was used for modeling such uncertainty. METHODS: An Italian database with 179 cases 18–70 years was divided randomly into developing (n = 20) and testing samples (n = 159). From the 159 registries of the testing sample, ...
- DOI:
- 10.1016/j.clnu.2012.02.014
- PubMed:
- 22445559
-
http://dx.doi.org/10.1016/j.clnu.2012.02.014
- Author:
- Batisse-Lignier, M.; Rousset, S.; Labbé, A.; Boirie, Y.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 625-629
- ISSN:
- 0261-5614
- Subject:
- correlation; weight gain; resting energy expenditure; children; infancy; adolescents; body mass index; lean body mass; birth weight
- Abstract:
- ... BACKGROUND & AIMS: : To determine if rapid growth between 0 and 2 years of life influences body composition and resting energy expenditure (REE) measured at 12–14 years in a population of obese children. METHODS: REE and body composition were measured in 107 obese children aged 12–14 years in whom weight at birth and 2 years was recorded. RESULTS: 46 obese children had a rapid growth between birth ...
- DOI:
- 10.1016/j.clnu.2012.03.001
- PubMed:
- 22464093
-
http://dx.doi.org/10.1016/j.clnu.2012.03.001
- Author:
- Dreesen, Mira; Foulon, Veerle; Vanhaecht, Kris; De Pourcq, Lutgart; Hiele, Martin; Willems, Ludo
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 602-608
- ISSN:
- 0261-5614
- Subject:
- developmental orthopedic disease; intravenous injection; guidelines; parenteral feeding; patients; systematic review; databases; adults
- Abstract:
- ... BACKGROUND & AIMS: Because home parenteral nutrition (HPN) in adult patients can give rise to a variety of complications, good guidance is necessary. To achieve this, clarity and consistency in guidelines are essential. The aim of this review is to identify and compare evidence-based guidelines, and to compile a list of main recommendations, according to their evidence-based grade. METHODS: We sea ...
- DOI:
- 10.1016/j.clnu.2012.02.013
- PubMed:
- 22424704
-
http://dx.doi.org/10.1016/j.clnu.2012.02.013
- Author:
- Haverkort, Elizabeth B.; Binnekade, Jan M.; de Haan, Rob J.; van Bokhorst - de van der Schueren, Marian A.E.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 647-651
- ISSN:
- 0261-5614
- Subject:
- adults; algorithms; body mass index; malnutrition; morbidity; mortality; patients; probability; quality of life; screening; weight loss
- Abstract:
- ... BACKGROUND & AIMS: Low handgrip strength by dynamometry is associated with increased postoperative morbidity, higher mortality and reduced quality of life. The aim of this study was to evaluate the accuracy of four algorithms in diagnosing malnutrition by measuring handgrip strength. METHODS: We included 504 consecutive preoperative outpatients. Reference standard for malnutrition was defined base ...
- DOI:
- 10.1016/j.clnu.2012.01.010
- PubMed:
- 22373791
-
http://dx.doi.org/10.1016/j.clnu.2012.01.010
- Author:
- D’Adamo, Christopher R.; Miller, Ram R.; Shardell, Michelle D.; Orwig, Denise L.; Hochberg, Marc C.; Ferrucci, Luigi; Semba, Richard D.; Yu-Yahiro, Janet A.; Magaziner, Jay; Hicks, Gregory E.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 659-665
- ISSN:
- 0261-5614
- Subject:
- alpha-carotene; alpha-tocopherol; anti-inflammatory activity; antioxidants; biomarkers; blood serum; clinical trials; equations; hip fractures; inflammation; interleukin-6; lutein; nutrient intake; patients; people; tumor necrosis factor-alpha
- Abstract:
- ... BACKGROUND & AIMS: Chronic inflammation impairs recovery among the 1.6 million people who suffer from hip fracture annually. Vitamin E and the carotenoids are two classes of dietary antioxidants with profound anti-inflammatory effects, and the goal of this study was to assess whether higher post-fracture concentrations of these antioxidants were associated with lower levels of interleukin 6 (IL-6) ...
- DOI:
- 10.1016/j.clnu.2012.01.013
- PubMed:
- 22365613
- PubMed Central:
- PMC3412071
-
http://dx.doi.org/10.1016/j.clnu.2012.01.013
- Author:
- Teixeira, Tatiana F.S.; Souza, Nilian C.S.; Chiarello, Paula G.; Franceschini, Sylvia C.C.; Bressan, Josefina; Ferreira, Célia L.L.F.; Peluzio, Maria do Carmo G.
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 735-740
- ISSN:
- 0261-5614
- Subject:
- animal models; anthropometric measurements; blood; blood pressure; body composition; chemical composition; correlation; excretion; fasting; females; glucose; high density lipoprotein; humans; insulin; lactulose; mannitol; metabolic syndrome; obesity; patients; permeability; risk factors; urine; volunteers; waist; women
- Abstract:
- ... BACKGROUND & AIMS: Altered intestinal permeability has been shown to be associated with metabolic alterations in animal models of obesity, but not in humans. The aim of this study was to assess intestinal permeability in obese women and verify if there is any association with anthropometric measurements, body composition or biochemical variables. METHODS: Twenty lean and twenty obese females parti ...
- DOI:
- 10.1016/j.clnu.2012.02.009
- PubMed:
- 22444236
-
http://dx.doi.org/10.1016/j.clnu.2012.02.009
- Author:
- Pontes-Arruda, Alessandro; Zaloga, Gary; Wischmeyer, Paul; Turpin, Robin; Liu, Frank X.; Mercaldi, Catherine
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 728-734
- ISSN:
- 0261-5614
- Subject:
- bags; blood flow; confidence interval; databases; observational studies; parenteral feeding; patients; prospective studies; regression analysis
- Abstract:
- ... BACKGROUND & AIMS: Parenteral nutrition is widely used in critically ill patients receiving nutritional support. Several previous studies associated the use of parenteral nutrition with the development of bloodstream infections. This study compared bloodstream infections in critical care patients receiving parenteral nutrition (PN) prepared via conventional compounding versus premixed multichamber ...
- DOI:
- 10.1016/j.clnu.2012.03.004
- PubMed:
- 22572624
-
http://dx.doi.org/10.1016/j.clnu.2012.03.004
- Author:
- Delamaire, Eloïse; Parnet, Patricia; Coupé, Bérengère; Hoebler, Christine; Blat, Sophie; Poupeau, Guillaume; Boquien, Clair-Yves; Champ, Martine; Darmaun, Dominique
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 741-748
- ISSN:
- 0261-5614
- Subject:
- adipocytes; adulthood; adults; animal models; blood serum; energy; food intake; glucose; infants; insulin; islets of Langerhans; leptin; low birth weight; low protein diet; metabolic syndrome; milk; mothers; pregnancy; protein content; protein metabolism; puberty; pups; rats; triacylglycerols; valine; weight gain
- Abstract:
- ... BACKGROUND & AIMS: Nutrition received in early life may impact adult health. The aim of the study was to determine whether high protein feeding in neonatal period would have long term metabolic effects in an animal model of low birth weight infants. METHODS: Male rat pups born from dams receiving a low protein diet during gestation were separated from their mothers, and equipped with gastrostomy t ...
- DOI:
- 10.1016/j.clnu.2012.02.005
- PubMed:
- 22414774
-
http://dx.doi.org/10.1016/j.clnu.2012.02.005
- Author:
- Cereda, Emanuele; Cassani, Erica; Barichella, Michela; Spadafranca, Angela; Caccialanza, Riccardo; Bertoli, Simona; Battezzati, Alberto; Pezzoli, Gianni
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 699-704
- ISSN:
- 0261-5614
- Subject:
- aspartate transaminase; diabetes mellitus; gender; waist circumference; underweight; risk profile; risk; glucose; alanine transaminase; patients; body fat; metabolic syndrome; blood lipids; triacylglycerols; fasting; nutrition assessment; body mass index; nutritional status; hypertension; cholesterol; low density lipoprotein; Parkinson disease
- Abstract:
- ... BACKGROUND & AIMS: To investigate if the reduced cardiometabolic risk in Parkinson's disease (PD) is independent of nutritional status, body composition and fat distribution. METHODS: We designed a case–control study comparing 80 non underweight PD patients with 80 controls matched for sex, age and body mass index (BMI). Nutritional assessment included: anthropometry (BMI and waist circumference [ ...
- DOI:
- 10.1016/j.clnu.2012.02.004
- PubMed:
- 22402420
-
http://dx.doi.org/10.1016/j.clnu.2012.02.004
- Author:
- Winter, Aaron; MacAdams, Jacqueline; Chevalier, Stéphanie
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 765-773
- ISSN:
- 0261-5614
- Subject:
- cachexia; glucose; hyperinsulinemia; insulin; insulin resistance; leucine; lung neoplasms; patients; protein synthesis; skeletal muscle
- Abstract:
- ... BACKGROUND & AIMS: Insulin resistance of protein anabolism has been speculated to underlie the skeletal muscle wasting characteristic of cancer cachexia. We tested whether insulin resistance is present in cachectic lung cancer patients and if a sustained, physiological elevation of amino acids with hyperinsulinemia would compensate for it. METHODS: Whole-body [¹³C]leucine and [³H]glucose kinetics ...
- DOI:
- 10.1016/j.clnu.2012.05.003
- PubMed:
- 22647419
-
http://dx.doi.org/10.1016/j.clnu.2012.05.003
- Author:
- Scheers, Tineke; Philippaerts, Renaat; Lefevre, Johan
- Source:
- Clinical nutrition 2012 v.31 no.5 pp. 756-764
- ISSN:
- 0261-5614
- Subject:
- adults; analysis of variance; body mass index; electronic equipment; men; obesity; physical activity; women
- Abstract:
- ... BACKGROUND & AIMS: Accurate data on domain-specific physical activity and sedentary behavior among normal-weight, overweight and obese adults are scarce. This study described a comprehensive physical (in)activity profile and examined variations in activity across the week. METHODS: Physical activity was measured in 442 Flemish adults (41.4 ± 9.8 years) for 7 days using the SenseWear Armband and an ...
- DOI:
- 10.1016/j.clnu.2012.04.011
- PubMed:
- 22595654
-
http://dx.doi.org/10.1016/j.clnu.2012.04.011