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- Thulasitha, William Shanthakumar, et al. Show all 6 Authors
- Comparative Biochemistry and Physiology, Part B 2014 v.176 pp. 18-33
- Oplegnathus fasciatus; amino acids; antioxidants; bacterial artificial chromosomes; binding sites; blood; brain; bream; copper; exons; gene expression; heart; homeostasis; introns; invertebrates; liver; mammals; messenger RNA; models; oxidative stress; phylogeny; potassium cyanide; quantitative polymerase chain reaction; recombinant proteins; screening; superoxide anion; superoxide dismutase; topology; transcription (genetics); transcription factors; zinc
- ... Superoxide dismutases (SODs) are dedicated to scavenge and dismutate the superoxide anions in order to protect the cells from oxidative stress by establishing the redox homeostasis. In this study, we describe a cytosolic Cu/ZnSOD, the second SOD member from rock bream Oplegnathus fasciatus (Of-cCu/ZnSOD) at molecular, genomic structural-, transcriptional- and functional-levels. The determination o ...