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- Bremer, K.; Kocha, K.M.; Snider, T.; Moyes, C.D.
- Comparative biochemistry and physiology 2016 v.199 pp. 4-12
- peroxisome proliferator-activated receptors, etc ; AMP-activated protein kinase; DNA-binding proteins; Danio rerio; acclimation; adenosine diphosphate; adenosine monophosphate; biogenesis; cold; cytochrome-c oxidase; energy; gene expression; genes; goldfish; hexokinase; mammals; messenger RNA; mitochondria; muscles; mutation; nuclear proteins; peptides; phosphorylation; Show all 23 Subjects
- ... Remodeling the muscle metabolic machinery in mammals in response to energetic challenges depends on the energy sensor AMP-activated protein kinase (AMPK) and its ability to phosphorylate PPAR γ coactivator 1 α (PGC1α), which in turn coactivates metabolic genes through direct and indirect association with DNA-binding proteins such as the nuclear respiratory factor 1 (NRF1) (Wu et al., 1999). The in ...