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- Mignolet, Johann; Panis, Gaël; Viollier, Patrick H
- Current opinion in microbiology 2018 v.42 pp. 79-86
- Caulobacter crescentus; DNA; Myxococcus; Neisseria; Pseudomonas; adhesion; cell cycle; fimbriae; genetic analysis; neonates; pathogens; protein transport; secretion; symbionts
- ... The Type IV pilus (T4P) is a powerful and sophisticated bacterial nanomachine involved in numerous cellular processes, including adhesion, DNA uptake and motility. Aside from the well-described subtype T4aP of the Gram-negative genera, including Myxococcus, Pseudomonas and Neisseria, the Tad (tight adherence) pilus secretion system re-shuffles homologous parts from other secretion systems along wi ...
- Gruber, Stephan
- Current opinion in microbiology 2018 v.42 pp. 96-103
- DNA; DNA damage; DNA replication; bacteria; cell viability; chromosome segregation; chromosome translocation; chromosomes; genome; transcription (genetics)
- ... Bacteria transcribe, duplicate and segregate their genomes all at once. Conflicts between DNA replication and active transcription are a major source of DNA damage and jeopardize genome integrity and cell survival. Co-orientation of replication forks and transcription units is thought to reduce the impact of such conflicts. Like transcription and replication, chromosome segregation relies on the t ...