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You searched for: Journal name Developmental and comparative immunology Remove constraint Journal name: Developmental and comparative immunology Publication year rev 7978-2022 Remove constraint Publication year rev: 7978-2022 Source 2022 v.126 Remove constraint Source: 2022 v.126
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1. Antimicrobial and immunomodulatory activity of beta-defensin from the Chinese spiny frog (Quasipaa spinosa)

Author:
Shui-Sheng Yu; Zeng-Hui Zhao; Xiao-Fei Gong; Xiao-Li Fan; Zhi-Hua Lin; Jie Chen
Source:
Developmental and comparative immunology 2022 v.126 pp. 104264
ISSN:
0145-305X
Subject:
Aeromonas hydrophila; Streptococcus iniae; Vibrio harveyi; Vibrio vulnificus; antibacterial properties; cell lines; cell membranes; frogs; immunomodulators; innate immunity; macrophages; mice; monocytes; necrosis; neoplasms; transcriptome
Abstract:
... The β-defensins are important components of the vertebrate innate immune system. While mammalian β-defensins have wide-ranging antibacterial and immunomodulatory activities, those of amphibians remain largely uncharacterised. In this study, β-defensin cDNA was identified from the skin transcriptome of the Chinese spiny frog Quasipaa spinosa. This β-defensin (QS-BD) consists of a signal and a matur ...
DOI:
10.1016/j.dci.2021.104264

2. Conservation of members of the free fatty acid receptor gene family in common carp

Author:
Jules Petit; Geert F. Wiegertjes
Source:
Developmental and comparative immunology 2022 v.126 pp. 104240
ISSN:
0145-305X
Subject:
Cyprinus carpio; G-protein coupled receptors; Lepisosteus oculatus; computer simulation; fish; free fatty acids; genes; genomics; homeostasis; humans; immune system; immunomodulation; intestinal microorganisms; phylogeny
Abstract:
... Accumulating evidence supports the crucial role intestinal microbiota and their metabolites play in the homeostasis of organisms. An important class of metabolites that have been shown to affect the immune system are short chain fatty acids (SCFAs). These SCFAs can affect the host cells via passive diffusion or via ligation to receptors, among others G-protein coupled receptor (GPR) 41 and 43. GPR ...
DOI:
10.1016/j.dci.2021.104240

3. Dietary administration of tyramine upregulates on immune resistance, carbohydrate metabolism, and biogenic amines in Macrobrachium rosenbergii

Author:
Hsin-Wei Kuo; Winton Cheng
Source:
Developmental and comparative immunology 2022 v.126 pp. 104236
ISSN:
0145-305X
Subject:
Lactococcus garvieae; Macrobrachium rosenbergii; blood glucose; carbohydrate metabolism; diet; dopamine; dose response; hemocytes; homeostasis; lactic acid; monophenol monooxygenase; norepinephrine; octopamine; phagocytosis; shrimp; survival rate; tyramine
Abstract:
... Survival rates of prawn, Macrobrachium rosenbergii, against Lactococcus garvieae, immune parameters, carbohydrate metabolism and biogenic amines were determined when the prawn were fed diets containing tyramine (TA) at the levels of 1 and 10 mg kg⁻¹. Results showed that prawn fed diets containing TA for 3 days, challenged with L. garvieae, and then continuously fed individually tested diets had a ...
DOI:
10.1016/j.dci.2021.104236

4. Immunization of chickens with Salmonella gallinarium ghosts expressing Salmonella Enteritidis NFliC-FimAC and CD40LC fusion antigen enhances cell-mediated immune responses and protects against wild-type challenges with both species

Author:
Amal Senevirathne; Chamith Hewawaduge; John Hwa Lee
Source:
Developmental and comparative immunology 2022 v.126 pp. 104265
ISSN:
0145-305X
Subject:
Salmonella Enteritidis; Western blotting; antibodies; antigens; bacteriophages; chickens; cytokines; genes; immunization; plasmids; serotypes; vaccines; vector control
Abstract:
... This study describes the construction and immunological characterization of a novel Salmonella gallinarium ghost vaccine to protect against S. gallinarium (SG) and S. Enteritidis (SE) serotypes. The SG ghost was designed to express N-terminus FliC (D0-D1 domain) and FimA retrieved from the SE genome, and the receptor-binding domain (RBD) of CD40L from the chicken as a single fusion construct. The ...
DOI:
10.1016/j.dci.2021.104265

5. Immunomodulatory role of short neuropeptide F in the mud crab Scylla paramamosain

Author:
Zhanning Xu; Yujie Wei; Huiyang Huang; Songlin Guo; Haihui Ye
Source:
Developmental and comparative immunology 2022 v.126 pp. 104260
ISSN:
0145-305X
Subject:
Scylla paramamosain; adenylate cyclase; cAMP-dependent protein kinase; crabs; cyclic AMP; ganglia; genes; hemocytes; hybridization; immune response; neuropeptides; nitric oxide; phagocytosis
Abstract:
... Short neuropeptide F (sNPF) is bioactive peptide secreted by neurons of invertebrates. It is one of the important pleiotropic neural molecules that is associated with a variety of physiological processes in invertebrates. However, little is known about the role of sNPF in the immune response. This study aimed to determine the distribution, localization, functional characteristics and signaling mec ...
DOI:
10.1016/j.dci.2021.104260

6. KLF13 induces apoptotic cell clearance in Penaeus vannamei as an essential part of shrimp innate immune response to pathogens

Author:
Shiyuan Bao; Chuchu Zhang; Jude Juventus Aweya; Defu Yao; Yongzhen Zhao; Tran Ngoc Tuan; Hongyu Ma; Yueling Zhang
Source:
Developmental and comparative immunology 2022 v.126 pp. 104242
ISSN:
0145-305X
Subject:
Litopenaeus vannamei; Streptococcus iniae; Vibrio parahaemolyticus; White spot syndrome virus; apoptosis; carcinogenesis; cell proliferation; hemocytes; immune response; inflammation; innate immunity; phylogeny; shrimp; transcription factors
Abstract:
... Although, in mammals, the Krüppel-like transcription factor 13 (KLF13) plays an essential role in cell proliferation, survival, differentiation, apoptosis, tumorigenesis, immune regulation, and inflammation, its role in penaeid shrimp is unclear. In the current study, we characterized a KLF13 homolog in Penaeus vannamei (PvKLF13), with full-length cDNA of 1677 bp and 1068 bp open reading frame (OR ...
DOI:
10.1016/j.dci.2021.104242

7. Presence of two RIG-I-like receptors, MDA5 and LGP2, and their dsRNA binding capacity in a perciform fish, the snakehead Channa argus

Author:
Lan Hao Liu; Yong-An Zhang; P. Nie; Shan Nan Chen
Source:
Developmental and comparative immunology 2022 v.126 pp. 104235
ISSN:
0145-305X
Subject:
Channa argus; Clupeiformes; Polypteriformes; cytoplasm; databases; fish; genes; genomics; innate immunity; phylogeny
Abstract:
... Fish retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are critical RNA sensors in cytoplasm and are involved in antiviral innate immunity. However, some species of fish lack RIG-I gene, and the function of RLR members in RIG-I-absent fish is poorly understood. In the present study, MDA5, LGP2 and MAVS genes were identified in commercially important snakehead Channa argus. But, RIG-I ge ...
DOI:
10.1016/j.dci.2021.104235

8. The role of complement in the tick cellular immune defense against the entomopathogenic fungus Metarhizium robertsii

Author:
Jéssica Fiorotti; Veronika Urbanová; Patrícia Silva Gôlo; Vânia Rita Elias Pinheiro Bittencourt; Petr Kopáček
Source:
Developmental and comparative immunology 2022 v.126 pp. 104234
ISSN:
0145-305X
Subject:
Ixodes ricinus; Lyme disease; Metarhizium robertsii; acaricides; biological insect control; complement; conidia; entomopathogenic fungi; hemocoel; hemocytes; immune response; models; mortality; phagocytosis; tick infestations; ticks
Abstract:
... Entomopathogenic fungi (EPF) have been widely explored for their potential in the biological control of insect pests and as an environmentally friendly alternative to acaricides for limiting tick infestation in the field. The arthropod cuticle is the main barrier against fungal infection, however, an understanding of internal defense mechanisms after EPF intrusion into the invertebrate hemocoel is ...
DOI:
10.1016/j.dci.2021.104234

9. A novel C-type lectin LvCTL 4.2 has antibacterial activity but facilitates WSSV infection in shrimp (L. vannamei)

Author:
Yu-Hsun Huang; Ramya Kumar; Chun-Hung Liu; Shih-Shun Lin; Han-Ching Wang
Source:
Developmental and comparative immunology 2022 v.126 pp. 104239
ISSN:
0145-305X
Subject:
Litopenaeus vannamei; Vibrio parahaemolyticus; White spot syndrome virus; antibacterial properties; growth retardation; hepatopancreas; innate immunity; lectins; necrosis; pathogenesis; pathogens; shrimp; signal peptide; stomach; virion; virus replication
Abstract:
... Glycan-binding protein C-type lectin (CTL), one of the pattern recognition receptors (PRRs), binds to carbohydrates on the surface of pathogens and elicits antimicrobial responses in shrimp innate immunity. The objective was to identify and characterize a novel C-type lectin LvCTL 4.2 in Litopenaeus vannamei. The LvCTL 4.2 protein consisted of a signal peptide at the N terminal and a carbohydrate- ...
DOI:
10.1016/j.dci.2021.104239

10. Alpinone: A positive regulator molecule of immune antiviral response in Atlantic salmon kidney cells

Author:
Almendra Benavides; Daniela Gutiérrez; Nadia Epuyao; Brenda Modak; Mónica Imarai; Beatriz Valenzuela
Source:
Developmental and comparative immunology 2022 v.126 pp. 104262
ISSN:
0145-305X
Subject:
Heliotropium; Salmo salar; Salmon isavirus; antiviral properties; disease severity; flavonoids; genes; kidneys; melanoma; mitochondria; quantitative polymerase chain reaction; salmon; transcription (genetics); tumor necrosis factor receptors; viruses
Abstract:
... Alpinone is a flavonoid obtained from the resinous exudate of Heliotropium huascoense. This flavonoid shows antiviral activity against the infectious salmon anemia virus (ISAV), which causes severe disease in farmed Atlantic salmon. Here, we aim to elucidate mechanisms underlying the antiviral effects of the flavonoid. In this regard, we evaluated whether Alpinone can act upregulating the pattern- ...
DOI:
10.1016/j.dci.2021.104262

11. An l-rhamnose-binding lectin from Nile tilapia (Oreochromis niloticus) possesses agglutination activity and regulates inflammation, phagocytosis and respiratory burst of monocytes/macrophages

Author:
Liangliang Mu; Xiaoxue Yin; Weiwei Qi; Jiadong Li; Hao Bai; Nuo Chen; Yanjian Yang; Bei Wang; Jianmin Ye
Source:
Developmental and comparative immunology 2022 v.126 pp. 104256
ISSN:
0145-305X
Subject:
Aeromonas hydrophila; Oreochromis niloticus; Streptococcus agalactiae; agglutination; fish; inflammation; intestines; kidneys; lectins; liver; macrophages; monocytes; phagocytosis; respiratory burst; spleen
Abstract:
... Rhamnose-binding lectins (RBLs), a Ca²⁺-independent lectin family, are widely present in vertebrates and invertebrates, which involve in the innate immune response. However, the functional characterization and related regulation mechanisms of RBLs remain unclear in teleost fish. In this study, an l-rhamnose-binding lectin-like (OnRBL-L) was identified and functionally characterized from Nile tilap ...
DOI:
10.1016/j.dci.2021.104256

12. Bombyx mori cypovirus (BmCPV) induces PINK1-Parkin mediated mitophagy via interaction of VP4 with host Tom40

Author:
Min Zhu; Jun Pan; Mingtian Zhang; Xinyu Tong; Yunshan Zhang; Ziyao Zhang; Zi Liang; Xing Zhang; Xiaolong Hu; Renyu Xue; Guangli Cao; Chengliang Gong
Source:
Developmental and comparative immunology 2022 v.126 pp. 104244
ISSN:
0145-305X
Subject:
Bombyx mori; Cypovirus; Western blotting; autophagosomes; electron microscopy; fluorescence; membrane proteins; midgut; mitochondria; mitochondrial membrane; mitophagy; rapamycin; silkworms; structural proteins; transfection; viruses
Abstract:
... The mechanism by which infection by Bombyx mori cytoplasmic nucleopolyhedrosis virus (BmCPV) causes autophagy has not been studied in detail. Herein we have observed by electron microscopy that infection with BmCPV causes autophagosome and mitochondrial structure damage in Bombyx mori midgut. In BmN cells infected with BmCPV and expressing eGFP-LC3, fluorescence spots and LC3-II levels increased, ...
DOI:
10.1016/j.dci.2021.104244

13. Characterization and functional analysis of a clip domain serine protease (MncSP) and its alternative transcript (MncSP-isoform) from Macrobrachium nipponense

Author:
Wei Qin; Yang Lu; Hongyu Wang; Beixiang Liu; Zuosheng Jiang; Chengxiang Zhou; Xin Huang; Xiaoling Dai; Qian Ren
Source:
Developmental and comparative immunology 2022 v.126 pp. 104237
ISSN:
0145-305X
Subject:
Macrobrachium nipponense; Staphylococcus aureus; Vibrio parahaemolyticus; crustin; exons; heart; hemocytes; hepatopancreas; innate immunity; intestines; introns; monophenol monooxygenase; nucleotides; phylogeny; prophenoloxidase; serine proteinases; signal peptide; stomach
Abstract:
... Clip domain serine protease (cSPs) play an important role in the innate immune defense of crustaceans. In this study, a clip domain serine protease (MncSP) and its alternative transcript (MncSP-isoform) were identified from Macrobrachium nipponense. The full-length cDNA sequences of MncSP and MncSP-isoform were 2447 and 2351 bp with open reading frames comprising 1497 and 1401 bp nucleotides and e ...
DOI:
10.1016/j.dci.2021.104237

14. Characterization of MDA5 and microRNA-203 negatively regulates the RLR signaling pathway via targeting MDA5 in miiuy croaker

Author:
Qing Chu; Jingjing Han; Lingping Sun; Junxia Cui; Tianjun Xu
Source:
Developmental and comparative immunology 2022 v.126 pp. 104259
ISSN:
0145-305X
Subject:
Miichthys miiuy; bioinformatics; bioluminescence assay; cytokines; evolution; fish; genes; genomics; immune response; microRNA; pathogens
Abstract:
... MDA5 is a member of retinoic acid-inducible gene I (RIG-I)-like receptors (RLR receptors), which may play a crucial role in the immune regulation process. Recently, microRNAs (miRNAs) have been shown to act as an important regulator in the RLRs signaling pathway. Additionally, the MDA5 gene, as a significant cytosolic pathogen recognition receptor (PRR), its characteristics and functions have been ...
DOI:
10.1016/j.dci.2021.104259

15. Characterization of the variable lymphocyte receptor B genes of a freshwater nonparasitic lamprey species, Lampetra hubbsi

Author:
Kyle L. Rekedal; Khan MA. Hassan; Chris T. Amemiya
Source:
Developmental and comparative immunology 2022 v.126 pp. 104241
ISSN:
0145-305X
Subject:
Lampetra; Petromyzon marinus; adaptive immunity; freshwater; immunoglobulins; leucine; organogenesis; rivers; California
Abstract:
... Agnathans possess a convergent adaptive immune system in comparison to that of jawed vertebrates. In lieu of immunoglobulins, agnathans deploy variable lymphocyte receptors (VLRs), single chain protein effector molecules consisting of leucine rich repeat modules. Foundational work for this discovery utilized the parasitic sea lamprey, Petromyzon marinus. However, for several reasons, it is desirab ...
DOI:
10.1016/j.dci.2021.104241

16. Consequences of the different order of immunoglobulin gene rearrangements in swine

Author:
Marek Sinkora; Katerina Stepanova; Jana Sinkorova
Source:
Developmental and comparative immunology 2022 v.126 pp. 104196
ISSN:
0145-305X
Subject:
B-lymphocytes; immunoglobulin genes; immunoglobulins; swine
Abstract:
... Swine use a reverse order of immunoglobulin chain rearrangement compared to humans and mice, and this altered and modified order should have measurable consequences. Here we perform new and defining experiments with developing and mature B cells, characterizing the B cell populations that do not exist in other species. First, we have finally confirmed that light chains κ and λ are rearranged and e ...
DOI:
10.1016/j.dci.2021.104196

17. DAK inhibits MDA5-mediated signaling in the antiviral innate immunity of black carp

Author:
Guancheng Liao; Ji Liu; Lijun Yin; Yixuan He; Guoxia Qiao; Wu Song; Yunfan He; Zhuoyi Deng; Jun Xiao; Hao Feng
Source:
Developmental and comparative immunology 2022 v.126 pp. 104255
ISSN:
0145-305X
Subject:
Mylopharyngodon piceus; antiviral properties; cytoplasm; fish; genes; humans; innate immunity; interferons; melanoma; precipitin tests; viruses
Abstract:
... Dihydroxyacetone kinase (DAK) functions as a negative regulator of melanoma differentiation-associated gene 5 (MDA5)-mediated interferon (IFN) production in human. To explore its role in teleost fish, DAK homologue of black carp (Mylopharyngodon piceus) has been cloned and characterized in this paper. The transcription of black carp DAK (bcDAK) variated in host cells in response to LPS, poly (I:C) ...
DOI:
10.1016/j.dci.2021.104255

18. Expression and functional characterization of the mannose receptor (MR) from Nile tilapia (Oreochromis niloticus) in response to bacterial infection

Author:
Xiaoxue Yin; Hao Bai; Liangliang Mu; Nuo Chen; Weiwei Qi; Yu Huang; Heyi Xu; Jichang Jian; Anli Wang; Jianmin Ye
Source:
Developmental and comparative immunology 2022 v.126 pp. 104257
ISSN:
0145-305X
Subject:
Oreochromis niloticus; amino acid sequences; amino acids; bacterial infections; fibronectins; fish; genes; immune response; intestines; kidneys; macrophages; mannose; monocytes; peptides; phagocytosis; spleen; tissue distribution
Abstract:
... Mannose receptor (MR) as a member of the pattern recognition receptors (PRRs) plays an important role in the immune response. In mammals, the role of MR in the regulation of phagocytosis is clarified; however, its contribution to opsonize phagocytosis remains unclear in bony fish. In this study, the expression pattern of Nile tilapia mannose receptor gene (OnMR) was investigated and its regulation ...
DOI:
10.1016/j.dci.2021.104257

19. Gut microbiome alterations in the crustacean Pacifastacus leniusculus exposed to environmental concentrations of antibiotics and effects on susceptibility to bacteria challenges

Author:
Ariadne Hernández-Pérez; Jesús Alejandro Zamora-Briseño; Kenneth Söderhäll; Irene Söderhäll
Source:
Developmental and comparative immunology 2022 v.126 pp. 104181
ISSN:
0145-305X
Subject:
Pacifastacus leniusculus; Vibrio; antibiotics; crayfish; homeostasis; immunology; intestinal microorganisms; intestines; sulfamethoxazole
Abstract:
... Gut-associated microbiota in crustaceans are recognized as a key element for maintaining homeostasis and health in the animal. Since the richness of these microbial communities is strongly influenced by the local environment, especially in aquatic organisms, it is important to address to what extent environmental variations can affect these communities. In the present study, we used high-throughpu ...
DOI:
10.1016/j.dci.2021.104181

20. Hemeprotein amplifies the innate immune receptors of Ctenopharyngodon idellus kidney cells through NF-κB- and MAPK-dependent reactive oxygen species generation

Author:
Zhijie Lu; Meizhen Tang; Menglan Zhang; Yanan Li; Fei Shi; Fanbin Zhan; Lijuan Zhao; Jun Li; Li Lin; Zhendong Qin
Source:
Developmental and comparative immunology 2022 v.126 pp. 104207
ISSN:
0145-305X
Subject:
Ctenopharyngodon idella; Toll-like receptor 2; aquaculture; catalase; cytotoxicity; glutathione; heme; heme oxygenase (biliverdin-producing); heme proteins; hemolysis; interleukin-6; intracellular signaling peptides and proteins; kidneys; ligands; lipopolysaccharides; mitogen-activated protein kinase; oligomerization; reactive oxygen species; secretion; superoxide dismutase
Abstract:
... Infectious bacterial and viral diseases that cause hemolysis are considered life-threatening to grass carp (Ctenopharyngodon idellus), which is a species used in aquaculture worldwide. After heme and hemeproteins (Hb) are released as a result of hemolysis, the effect of excess Hb and heme on tissues remains to be characterized. To decipher the mechanisms, after incubation with Hb, we showed that l ...
DOI:
10.1016/j.dci.2021.104207