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- Jiang, Shuai, et al. Show all 10 Authors
- Developmental and comparative immunology 2018 v.89 pp. 152-162
- Crassostrea gigas; Western blotting; cathepsins; cell-mediated immunity; coumarin; cysteine proteinases; dose response; flow cytometry; fluorescence; gene expression; gene expression regulation; genetic markers; granulocytes; hemocytes; hepatopancreas; immune response; immunohistochemistry; messenger RNA; oysters; pathogens; phagocytes; proteins; proteolysis; tissues
- ... Cathepsin L1 (CTSL1) is a lysosomal cysteine protease with a papain-like structure. It is known to be implicated in multiple processes of immune response against pathogen infection based on the proteolytic activity. In the present study, a CTSL1 homologue (designated as CgCTSL1) was identified from Crassostrea gigas. It contained a typically single Pept_C1 domain with three conserved catalytically ...