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- Frankowiack, Marcel; Olsson, Mia; Cluff, H. Dean; Evans, Alina L.; Hellman, Lars; Månsson, Johan; Arnemo, Jon M.; Hammarström, Lennart
- Developmental and comparative immunology 2015 v.50 no.1 pp. 26-28
- Scandinavia, etc ; Canis lupus; blood serum; dog breeds; dogs; humans; immunoglobulin A; immunosuppression; wolves; Canada; Show all 10 Subjects
- ... Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in both humans and selected breeds of domestic dogs. In both species, IgAD is associated with recurrent infections and immune mediated diseases. Previous results imply that IgAD is also common in the wild ancestor of domestic dogs, the gray wolf. Here, we report that serum IgA concentrations are significantly different ...