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Developmental and comparative immunology
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G-protein coupled receptors
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- Author:
- Ewa Szwejser; Magdalena Maciuszek; Ayako Casanova-Nakayama; Helmut Segner; B.M. Lidy Verburg-van Kemenade; Magdalena Chadzinska
- Source:
- Developmental and comparative immunology 2017 v.66 pp. 61-72
- ISSN:
- 0145-305X
- Subject:
- Cyprinus carpio; G-protein coupled receptors; carp; estradiol; estrogen receptors; immunologic receptors; kidneys; lymphocytes; macrophages; monocytes; neutrophils; phosphatidylinositol 3-kinase; reactive oxygen species
- Abstract:
- ... Estrogens are important for bi-directional neuroendocrine-immune interaction. They act via nuclear estrogen receptors (ERα and ERβ) and/or G-protein coupled receptor - GPR30.We found expression of ERα, ERβ and GPR30 in carp lymphoid tissues and head kidney monocytes/macrophages, neutrophils and lymphocytes. Interestingly, ERβ is also expressed in some head kidney lymphocytes but not in naive PBLs. ...
- DOI:
- 10.1016/j.dci.2016.04.003
- https://doi.org/10.1016/j.dci.2016.04.003
- Author:
- Jules Petit; Geert F. Wiegertjes
- Source:
- Developmental and comparative immunology 2022 v.126 pp. 104240
- ISSN:
- 0145-305X
- Subject:
- Cyprinus carpio; G-protein coupled receptors; Lepisosteus oculatus; computer simulation; fish; free fatty acids; genes; genomics; homeostasis; humans; immune system; immunomodulation; intestinal microorganisms; phylogeny
- Abstract:
- ... Accumulating evidence supports the crucial role intestinal microbiota and their metabolites play in the homeostasis of organisms. An important class of metabolites that have been shown to affect the immune system are short chain fatty acids (SCFAs). These SCFAs can affect the host cells via passive diffusion or via ligation to receptors, among others G-protein coupled receptor (GPR) 41 and 43. GPR ...
- DOI:
- 10.1016/j.dci.2021.104240
- https://doi.org/10.1016/j.dci.2021.104240
- Author:
- Feifei Xu; Dan He; Ruihong Ning; Bo Zeng; Cody W. Thompson; Ying Li; Dawei Wang; Yan Li
- Source:
- Developmental and comparative immunology 2019 v.98 pp. 80-88
- ISSN:
- 0145-305X
- Subject:
- G-protein coupled receptors; Mus musculus; Rattus norvegicus; chemokines; genetic variation; immune response; ligands; mice; models
- Abstract:
- ... The chemokine ligand XCL1 plays critical roles in immune responses with diverse physiological and pathological implications through interactions with a cognate G protein-coupled receptor XCR1. To shed insight into their versatile nature, we analyzed genetic variations of XCL1 and XCR1 in murine rodents, including commonly-used model organisms Mus musculus (house mouse) and Rattus norvegicus (Norwa ...
- DOI:
- 10.1016/j.dci.2019.04.008
- https://doi.org/10.1016/j.dci.2019.04.008
- Author:
- Zhaoqun Liu; Zhi Zhou; Lingling Wang; Shuai Jiang; Weilin Wang; Ran Zhang; Linsheng Song
- Source:
- Developmental and comparative immunology 2015 v.49 no.2 pp. 217-224
- ISSN:
- 0145-305X
- Subject:
- Crassostrea gigas; G-protein coupled receptors; amino acids; antagonists; antibacterial properties; calcium; complementary DNA; cyclic AMP; gills; hemocytes; hepatopancreas; homeostasis; immune response; immunocytes; immunomodulation; kidneys; ligands; messenger RNA; muscles; narcotics; oysters; pathogens; second messengers
- Abstract:
- ... Opioid receptors (OR) are a group of G protein-coupled receptors with opioids as ligands, which play an important role in triggering the second messengers to modulate immune response in vertebrate immunocytes. In the present study, the full length cDNA of a homologue of δ-opioid receptor (DOR) for [Met5]-enkaphalin was cloned from oyster Crassostrea gigas (designated as CgDOR), which was 1104 bp e ...
- DOI:
- 10.1016/j.dci.2014.11.017
- https://doi.org/10.1016/j.dci.2014.11.017
- Author:
- Xingkun Jin; Weiwei Li; Minjie Xu; Youting Zhu; Yan Zhou; Qun Wang
- Source:
- Developmental and comparative immunology 2019 pp. 103457
- ISSN:
- 0145-305X
- Subject:
- Eriocheir sinensis; G-protein coupled receptors; aquaculture; blood circulation; disease control; enzyme activity; gene expression regulation; genes; hemocytes; immune response; innate immunity; lipopolysaccharides; microorganisms; mitogen-activated protein kinase; peptidoglycans; quantitative polymerase chain reaction; sequence analysis
- Abstract:
- ... Knowledge about how Eriocheir sinensis interacts with microorganisms in its ambient environment is still lacking. Using RNA-Seq, we determined the most conserved genes and pathways compared with other animals and detected highly-induced immune genes in E. sinensis hemocytes post-in vivo challenge with different microbial derivatives. In total, 33.2 million high-quality reads were generated and ass ...
- DOI:
- 10.1016/j.dci.2019.103457
- https://doi.org/10.1016/j.dci.2019.103457
6. Tyramine's modulation of immune resistance functions in Litopenaeus vannamei and its signal pathway
- Author:
- Hsin-Wei Kuo; Chin-Chyuan Chang; Winton Cheng
- Source:
- Developmental and comparative immunology 2019 pp. -
- ISSN:
- 0145-305X
- Subject:
- G-protein coupled receptors; Litopenaeus vannamei; Vibrio alginolyticus; antagonists; hemocytes; immunocompetence; insects; lysozyme; monophenol monooxygenase; mortality; octopamine; phagocytosis; propranolol; respiratory burst; shrimp; signal transduction; tyramine
- Abstract:
- ... Tyramine (TA), a neuroactive chemical, plays various important physiological roles in insects by activating distinct G-protein-coupled receptors (GPCRs). In this study, we investigated the effects of by pharmacological injection of TA on immune resistance regulation and its signal pathway in white shrimp Litopenaeus vannamei. Results showed significant increases in the total haemocyte count (THC), ...
- DOI:
- 10.1016/j.dci.2019.01.008
- https://doi.org/10.1016/j.dci.2019.01.008