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- Author:
- Jiang, Shuai, et al. ; Li, Yiqun; Song, Xiaorui; Wang, Weilin; Wang, Lingling; Yi, Qilin; Jia, Zhihao; Du, Xinyu; Qiu, Limei; Song, Linsheng; Show all 10 Authors
- Source:
- Developmental and comparative immunology 2017 v.71 pp. 59-69
- ISSN:
- 0145-305X
- Subject:
- Crassostrea gigas; DNA replication; Vibrio splendidus; cytoplasm; hematopoiesis; hemocytes; immune response; oysters; pathogens; porosity; protein synthesis; seawater; stem cells; transcription (genetics); transcription factors
- Abstract:
- ... Increasing evidences have demonstrated that the invertebrate gill is a predominant tissue participating in the immune response during pathogen challenge. In the present study, the hematopoiesis and immune activities in gill of Pacific oyster Crassostrea gigas were investigated. Stem-like cells with big nuclei and thin cytoplasm were found in the tubules of gill filaments, where DNA synthesis is ac ...
- DOI:
- 10.1016/j.dci.2017.01.024
-
https://dx.doi.org/10.1016/j.dci.2017.01.024
- Author:
- Jiang, Shuai, et al. ; Liu, Conghui; Zhang, Tao; Wang, Lingling; Wang, Mengqiang; Wang, Weilin; Jia, Zhihao; Song, Linsheng; Show all 8 Authors
- Source:
- Developmental and comparative immunology 2016 v.63 pp. 163-170
- ISSN:
- 0145-305X
- Subject:
- Crassostrea gigas; Escherichia coli; Micrococcus luteus; Staphylococcus aureus; Vibrio anguillarum; Vibrio splendidus; Yarrowia lipolytica; antioxidant activity; cell adhesion; cell-mediated immunity; copper; divalent metals; gene expression; gene expression regulation; glycoproteins; hemocytes; lipopolysaccharides; messenger RNA; metal ions; microorganisms; oxidative stress; oysters; superoxide dismutase
- Abstract:
- ... Extracellular superoxide dismutase (EcSOD) is a copper-containing glycoprotein playing an important role in antioxidant defense of living cells exposed to oxidative stress, and also participating in microorganism internalization and cell adhesion in invertebrates. EcSOD from oyster (designated CgEcSOD) had been previously reported to bind lipopolysaccharides (LPS) and act as a bridge molecule in V ...
- DOI:
- 10.1016/j.dci.2016.06.002
-
https://dx.doi.org/10.1016/j.dci.2016.06.002
- Author:
- Jiang, Shuai, et al. ; Liu, Conghui; Wang, Mengqiang; Wang, Lingling; Chen, Hao; Xu, Jiachao; Lv, Zhao; Song, Linsheng; Show all 8 Authors
- Source:
- Developmental and comparative immunology 2016 v.61 pp. 136-144
- ISSN:
- 0145-305X
- Subject:
- Crassostrea gigas; Vibrio splendidus; amino acids; apoptosis; cell membranes; complementary DNA; cytokines; dose response; gene expression; genes; hemocytes; immune response; immunoglobulins; lectins; lipopolysaccharides; messenger RNA; oysters; palps; peptidoglycans; phagocytosis; polyclonal antibodies; polypeptides; sequence homology; sialic acids; signal transduction; vertebrates
- Abstract:
- ... Sialic acid binding immunoglobulin-type lectin (siglec) belongs to the immunoglobulin superfamily (IgSF), which acts as regulator involved in glycan recognition and signal transduction in the immune and nervous systems. In the present study, a siglec gene (designated CgSiglec-1) was characterized from the Pacific oyster, Crassostrea gigas. The cDNA of CgSiglec-1 was of 1251 bp encoding a predicted ...
- DOI:
- 10.1016/j.dci.2016.03.026
-
https://dx.doi.org/10.1016/j.dci.2016.03.026
- Author:
- Jiang, Shuai, et al. ; Jia, Zhihao; Zhang, Tao; Wang, Mengqiang; Cheng, Qi; Sun, Mingzhe; Wang, Lingling; Song, Linsheng; Show all 8 Authors
- Source:
- Developmental and comparative immunology 2015 v.53 no.1 pp. 253-264
- ISSN:
- 0145-305X
- Subject:
- Crassostrea gigas; Gram-negative bacteria; Gram-positive bacteria; Staphylococcus aureus; Vibrio splendidus; amino acids; apoptosis; binding capacity; cell adhesion; complementary DNA; dissociation; dose response; gene expression; hemocytes; hepatopancreas; integrins; latex; lipopolysaccharides; messenger RNA; muscles; open reading frames; oysters; peptidoglycans; phagocytosis; polyclonal antibodies; polypeptides
- Abstract:
- ... Integrins are a family of cell adhesion molecules which play important roles in the regulation of cell adhesion, migration, proliferation, apoptosis and phagocytosis. In the present study, the immune function of an integrin from the oyster Crassostrea gigas (designated CgIntegrin) was characterized to understand the regulatory mechanism of hemocyte phagocytosis toward different microbes. The full- ...
- DOI:
- 10.1016/j.dci.2015.07.014
-
https://dx.doi.org/10.1016/j.dci.2015.07.014