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You searched for: Author "Thulasitha, William Shanthakumar" Remove constraint Author: "Thulasitha, William Shanthakumar" Journal Developmental and comparative immunology Remove constraint Journal: Developmental and comparative immunology Subject bacteria Remove constraint Subject: bacteria Subject amino acids Remove constraint Subject: amino acids
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1. A proto-type galectin-2 from rock bream (Oplegnathus fasciatus): Molecular, genomic, and expression analysis, and recognition of microbial pathogens by recombinant protein

Author:
Thulasitha, William Shanthakumar,   et al.   ; Umasuthan, Navaneethaiyer; Wan, Qiang; Nam, Bo-Hye; Kang, Tae-Wook; Lee, Jehee;     Show all 6 Authors
Source:
Developmental and comparative immunology 2017 v.71 pp. 70-81
ISSN:
0145-305X
Subject:
polypeptides; bream; recombinant proteins; amino acids; intestines; carbohydrate binding; screening; introns; tissues; pathogens; sequence analysis; lactose; complementary DNA; Oplegnathus fasciatus; exons; hemagglutination; liver; galactose; lectins; bacteria
Abstract:
... A β-galactoside binding lectin, designated as galectin-2, was identified and characterized from rock bream Oplegnathus fasciatus (OfGal-2). The cDNA of OfGal-2 comprised of 692 bp with a coding sequence of 396 bp, encoding a putative polypeptide of 131 amino acids. Gene structure analysis of OfGal-2 revealed a four exon-three intron organization. A single carbohydrate-binding domain containing all ...
DOI:
10.1016/j.dci.2017.01.023

2. A galectin related protein from Oplegnathus fasciatus: Genomic, molecular, transcriptional features and biological responses against microbial pathogens

Author:
Thulasitha, William Shanthakumar,   et al.   ; Whang, Ilson; Umasuthan, Navaneethaiyer; Kang, Hyun-Sil; Mothishri, M.S.; Lee, Seongdo; Qiang, Wan; Noh, Jae Koo; Lee, Jehee;     Show all 9 Authors
Source:
Developmental and comparative immunology 2016 v.56 pp. 13-24
ISSN:
0145-305X
Subject:
Edwardsiella tarda; Escherichia coli; Listeria monocytogenes; Miamiensis avidus; Oplegnathus fasciatus; Streptococcus iniae; Vibrio tapetis; amino acids; bacteria; bacterial artificial chromosomes; bream; carbohydrate binding; complement; complementary DNA; exons; gene expression; genomic libraries; gills; introns; lectins; messenger RNA; open reading frames; parasites; pathogens; phagocytosis; phylogeny; receptors; sequence alignment; signal peptide; spleen; transcription (genetics)
Abstract:
... Galectins, a family of β-galactoside-binding lectins, are pattern recognition receptors that recognize pathogen-associated molecular patterns and are subsequently involved in the opsonization, phagocytosis, complement activation, and killing of microbes. Here, we report a novel galectin related protein (GRP) identified from rock bream (Oplegnathus fasciatus), designated OfGal like B. The cDNA of O ...
DOI:
10.1016/j.dci.2015.11.011