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- Author:
- Dela, Flemming, et al. ; Højbjerre, Lise; Sonne, Mette Paulli; Alibegovic, Amra Ciric; Nielsen, Ninna Bo; Vaag, Allan; Bruun, Jens Meldgaard; Stallknecht, Bente; Show all 8 Authors
- Source:
- Diabetes care 2011 v.34 no.10 pp. 2265-2272
- ISSN:
- 0149-5992
- Subject:
- C-reactive protein; adiponectin; adipose tissue; blood; body mass index; chemoattractants; gene expression; inflammation; insulin resistance; interleukin-10; leptin; messenger RNA; necrosis; noninsulin-dependent diabetes mellitus; obesity; patients; people; risk; tumor necrosis factor-alpha
- Abstract:
- ... OBJECTIVE: First-degree relatives (FDRs) of patients with type 2 diabetes may exhibit a disproportionately elevated risk of developing insulin resistance, obesity, and type 2 diabetes when exposed to physical inactivity, which to some unknown extent may involve low-grade inflammation. We investigated whether subjects who are nonobese FDRs show signs of low-grade inflammation before or after exposu ...
- DOI:
- 10.2337/dc11-0631
- PubMed:
- 21836102
- PubMed Central:
- PMC3177724
-
http://dx.doi.org/10.2337/dc11-0631