Jump to Main Content
- Focks, Andreas; Belgers, Dick; Boerwinkel, Marie-Claire; Buijse, Laura; Roessink, Ivo; Van den Brink, Paul J.
- Ecotoxicology 2018 v.27 no.7 pp. 992-1007
- threshold models, etc ; Ephemeroptera; aquatic invertebrates; data collection; ecotoxicology; environmental assessment; exposure profile; imidacloprid; macroinvertebrates; model validation; prediction; thiacloprid; thiamethoxam; toxicity; uncertainty; Show all 15 Subjects
- ... Exposure patterns in ecotoxicological experiments often do not match the exposure profiles for which a risk assessment needs to be performed. This limitation can be overcome by using toxicokinetic-toxicodynamic (TKTD) models for the prediction of effects under time-variable exposure. For the use of TKTD models in the environmental risk assessment of chemicals, it is required to calibrate and valid ...