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- Beck, Alain, et al. Show all 6 Authors
- Electrophoresis 2018 v.39 no.16 pp. 2083-2090
- Food and Drug Administration; cellulose; coatings; electrophoresis; hospitals; hydrophobicity; monoclonal antibodies; pH; polyethylene glycol; quality control
- ... The determination of mAb critical quality attributes (CQA) is crucial for their successful application in health diseases. A generic CZE method was developed for the high‐resolution separation of various mAb charge variants, which are often recognized as important CQA. A dynamic coating of the capillary was obtained with polyethylene oxide (PEO), whereas Bis‐Tris allowed the analysis of mAbs under ...