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- Gold, Mark S., et al. Show all 8 Authors
- Electrophoresis 2011 v.32 no.13 pp. 1692-1705
- Alzheimer disease; Parkinson disease; Western blotting; animal models; brain; electrophoresis; glyceraldehyde 3-phosphate; oxidative stress; pathogenesis; post-translational modification; synthetic peptides; tyrosine; ubiquitin
- ... Protein tyrosine nitration is a post-translational modification commonly used as a marker of cellular oxidative stress associated with numerous pathophysiological conditions. We focused on ubiquitin carboxyl terminal hydrolase-L1 (UCH-L1) and glyceraldehyde-3-phosphate (GAPDH) which are high-abundant brain proteins that have been identified to be highly susceptible to oxidative modification. Both ...