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- Heo, SungKu; Safder, Usman; Yoo, ChangKyoo
- Environmental pollution 2019 v.253 pp. 29-38
- endocrine system, etc ; artificial intelligence; ecotoxicology; endocrine-disrupting chemicals; estrogen receptors; human health; humans; in vitro studies; models; quantitative analysis; quantitative structure-activity relationships; sex hormone-binding globulin; statistical analysis; Show all 13 Subjects
- ... Over 80,000 endocrine-disrupting chemicals (EDCs) are considered emerging contaminants (ECs), which are of great concern due to their effects on human health. Quantitative structure-activity relationship (QSAR) models are a promising alternative to in vitro methods to predict the toxicological effects of chemicals on human health. In this study, we assessed a deep-learning based QSAR (DL-QSAR) mod ...
- Renaud, Ludivine; Agarwal, Nisha; Richards, Dylan J.; Falcinelli, Silvia; Hazard, E. Starr; Carnevali, Oliana; Hyde, John; Hardiman, Gary
- Environmental pollution 2019 v.244 pp. 926-937
- endocrine system, etc ; RNA; Sardinops sagax; Scomber japonicus; cost effectiveness; diagnostic techniques; endocrine-disrupting chemicals; estrogens; fish feeding; genes; genomics; high-throughput nucleotide sequencing; laboratory experimentation; liver; mackerel; marine environment; monitoring; municipal wastewater; nucleotide sequences; pollutants; risk; risk assessment; rivers; sardines; screening; sediments; transcription (genetics); transcriptomics; Show all 28 Subjects
- ... Endocrine disrupting chemicals (EDCs) are substances which disrupt normal functioning of the endocrine system by interfering with hormone regulated physiological pathways. Aquatic environments provide the ultimate reservoir for many EDCs as they enter rivers and the ocean via effluent discharges and accumulate in sediments. One EDC widely dispersed in municipal wastewater effluent discharges is 17 ...