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- Ali, Haytham A., et al. Show all 6 Authors
- Environmental science and pollution research international 2019 v.26 no.12 pp. 12368-12378
- acceptable daily intake; alkaline phosphatase; apoptosis; aspartate transaminase; caspase-3; catalase; cell proliferation; chlorophyll; chronic exposure; collagen; creatinine; fibronectins; fibrosis; food colorants; genes; hepatocytes; histopathology; immunohistochemistry; kidneys; liver; messenger RNA; necrosis; rats; signal transduction; superoxide dismutase; tartrazine; urea
- ... Colouring agents are highly present in diverse products in the human environment. We aimed to elucidate the fibrogenic cascade triggered by the food dyes tartrazine and chlorophyll. Rats were orally given distilled water, tenfold of the acceptable daily intake of tartrazine, or chlorophyll for 90 consecutive days. Tartrazine-treated rats displayed a significant rise (p < 0.05) in the mRNA levels a ...