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- Shin, Jong-Shik, et al. Show all 2 Author
- Enzyme and microbial technology 2011 v.49 no.4 pp. 380-387
- Paracoccus denitrificans; activation energy; active sites; amines; energy; engineering; enzyme substrates; ketones; pH
- ... ω-Transaminase (ω-TA) is the only naturally occurring enzyme allowing asymmetric amination of ketones for production of chiral amines. The active site of the enzyme was proposed to consist of two differently sized substrate binding pockets and the stringent steric constraint in the small pocket has presented a significant challenge to production of structurally diverse chiral amines. To provide a ...