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- Author:
- Dittrich, Manja; Jahreis, Gerhard; Bothor, Kristin; Drechsel, Carina; Kiehntopf, Michael; Blüher, Matthias; Dawczynski, Christine
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 881-893
- ISSN:
- 1436-6207
- Subject:
- alpha-linolenic acid; blood lipids; cholesterol; cross-over studies; docosahexaenoic acid; eicosapentaenoic acid; enriched foods; erythrocytes; fatty acid composition; food consumption; high density lipoprotein; linoleic acid; linseed; linseed oil; long chain polyunsaturated fatty acids; low density lipoprotein; microalgae; omega-3 fatty acids; placebos; risk factors; sunflower oil; triacylglycerols; vegetable oil
- Abstract:
- ... PURPOSE: The aim of the study was to investigate the influence of foods enriched with vegetable oils varying in their n-3 polyunsaturated fatty acids profile on cardiovascular risk factors for hypertriglyceridemic subjects. METHODS: Fifty-nine hypertriglyceridemic subjects (triglycerides ≥ 1.5 mmol/L) were included in the randomized, double-blind, placebo-controlled, crossover study. The placebo g ...
- DOI:
- 10.1007/s00394-014-0764-2
-
http://dx.doi.org/10.1007/s00394-014-0764-2
- Author:
- Praagman, Jaike; Franco, Oscar H.; Ikram, M. Arfan; Soedamah-Muthu, Sabita S.; Engberink, Mariëlle F.; van Rooij, Frank J. A.; Hofman, Albert; Geleijnse, Johanna M.
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 981-990
- ISSN:
- 1436-6207
- Subject:
- coronary disease; dairy consumption; diabetes; high fat dairy products; low fat dairy products; milk; models; risk; stroke
- Abstract:
- ... PURPOSE: We examined whether consumption of total dairy and dairy subgroups was related to incident stroke and coronary heart disease (CHD) in a general older Dutch population. METHODS: The study involved 4,235 participants of the Rotterdam Study aged 55 and over who were free of cardiovascular disease (CVD) and diabetes at baseline (1990–1993). Multivariable Cox proportional hazards models were u ...
- DOI:
- 10.1007/s00394-014-0774-0
-
http://dx.doi.org/10.1007/s00394-014-0774-0
- Author:
- Ricciardi, Carolyn J.; Bae, Jiyoung; Esposito, Debora; Komarnytsky, Slavko; Hu, Pan; Chen, Jiangang; Zhao, Ling
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 1001-1012
- ISSN:
- 1436-6207
- Subject:
- adenosine triphosphate; adipocytes; adults; animal models; brown adipose tissue; energy expenditure; enzymes; gene overexpression; heat production; humans; knockout mutants; messenger RNA; mice; obesity; oxygen consumption; transcriptional activation; vitamin D
- Abstract:
- ... PURPOSE: The vitamin D system plays a role in metabolism regulation. 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) suppressed 3T3-L1 white adipocyte differentiation. Vitamin D receptor (VDR) knockout mice showed increased energy expenditure, whereas mice with adipose-specific VDR over-expression showed decreased energy expenditure. Brown adipose tissue (BAT), now known to be present in adult humans, func ...
- DOI:
- 10.1007/s00394-014-0778-9
-
http://dx.doi.org/10.1007/s00394-014-0778-9
- Author:
- Jurgoński, Adam; Fotschki, Bartosz; Juśkiewicz, Jerzy
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 991-999
- ISSN:
- 1436-6207
- Subject:
- adverse effects; analysis of variance; black currants; blood lipids; canola; diet; glycolysis; high density lipoprotein cholesterol; hindgut; intestines; lipid content; lipid metabolism; liver; males; metabolic diseases; obesity; rapeseed oil; rats; risk; short chain fatty acids; triacylglycerols
- Abstract:
- ... PURPOSE: It was hypothesised that blackcurrant seed oil beneficially modulates metabolic disorders related to obesity and its complications. The study also aimed to investigate the potentially adverse effects of an unbalanced diet on the distal intestine. METHODS: Male Wistar rats were randomly assigned to four groups of eight animals each and were fed a basal or obesogenic (high in fat and low in ...
- DOI:
- 10.1007/s00394-014-0775-z
- PubMed:
- 25311060
- PubMed Central:
- PMC4540767
-
http://dx.doi.org/10.1007/s00394-014-0775-z
- Author:
- Bryk, Gabriel; Coronel, Magalí Zeni; Pellegrini, Gretel; Mandalunis, Patricia; Rio, María Ester; de Portela, María Luz Pita Martín; Zeni, Susana Noemí
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 913-923
- ISSN:
- 1436-6207
- Subject:
- absorption; bone density; bone mineralization; calcium; cecum; femur; homeostasis; magnesium; mineral content; models; modulus of elasticity; osteoblasts; pH; prebiotics; rats; skeletal development; tibia; weanlings
- Abstract:
- ... AIM: Increasing calcium intake is the most effective strategy for avoiding Ca deficit. However, if intake remains inadequate, improving Ca absorption becomes an important tool to optimize Ca homeostasis and bone health. PURPOSE: The effect of a mixture of GOS/FOS® 9:1 added to a normal- or low-Ca diets on Ca absorption and bone mineralization, density and structure was investigated, in a model of ...
- DOI:
- 10.1007/s00394-014-0768-y
-
http://dx.doi.org/10.1007/s00394-014-0768-y
- Author:
- Patil, Prasad; Mandal, Surajit; Tomar, Sudhir Kumar; Anand, Santosh
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 863-880
- ISSN:
- 1436-6207
- Subject:
- functional foods; dipeptidyl-peptidase IV; in vitro studies; milk proteins; alpha-glucosidase; human health; milk; noninsulin-dependent diabetes mellitus; digestive enzymes; satiety; field experimentation; secretin; clinical trials; hyperinsulinemia
- Abstract:
- ... BACKGROUND: Type 2 diabetes (T2D), one of the major common human health problems, is growing at an alarming rate around the globe. Alpha-glucosidase and dipeptidyl peptidase IV (DPP-IV) enzymes play a significant role in development of T2D. Hence, reduction or inhibition of their activity can be one of the important strategies in management of T2D. Studies in the field of bioactive peptides have s ...
- DOI:
- 10.1007/s00394-015-0974-2
-
http://dx.doi.org/10.1007/s00394-015-0974-2
- Author:
- Scazzina, Francesca; Dall’Asta, Margherita; Pellegrini, Nicoletta; Brighenti, Furio
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 1021-1026
- ISSN:
- 1436-6207
- Subject:
- biscuits; breads; breakfast; cakes; digestibility; food industry; glucose; gluten; gluten-free foods; glycemic effect; glycemic index; nutritive value; pasta; starch; volunteers; Italy
- Abstract:
- ... PURPOSE: Gluten-free products present major challenges for the food industry in terms of organoleptic, technological and nutritional characteristics. The absence of gluten has been shown to affect starch digestibility, thus increasing the postprandial glycaemic response. However, in recent years, gluten-free technologies have been improved, thus possibly modifying this quality parameter. We invest ...
- DOI:
- 10.1007/s00394-014-0783-z
-
http://dx.doi.org/10.1007/s00394-014-0783-z
- Author:
- Sadi, Gokhan; Ergin, Volkan; Yilmaz, Guldal; Pektas, M. Bilgehan; Yildirim, O. Gokhan; Menevse, Adnan; Akar, Fatma
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 895-904
- ISSN:
- 1436-6207
- Subject:
- beverages; corn; diet; drinking water; endothelial nitric oxide synthase; fatty liver; fatty-acid synthase; genes; high fructose corn syrup; inducible nitric oxide synthase; insulin; insulin receptors; liver; messenger RNA; rats; resveratrol; triacylglycerols
- Abstract:
- ... PURPOSE: The increased consumption of high-fructose corn syrup (HFCS) may contribute to the worldwide epidemic of fatty liver. In this study, we have investigated whether HFCS intake (20 % beverages) influences lipid synthesis and accumulation in conjunction with insulin receptor substrate-1/2 (IRS-1; IRS-2), endothelial nitric oxide synthase (eNOS), sirtuin 1 (SIRT1) and inducible NOS (iNOS) expr ...
- DOI:
- 10.1007/s00394-014-0765-1
-
http://dx.doi.org/10.1007/s00394-014-0765-1
- Author:
- Lv, Shengmin; Zhao, Yinglu; Li, Yanxia; Wang, Yuchun; Liu, Hua; Li, Yang; Zhao, Jun; Rutherford, Shannon
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 905-912
- ISSN:
- 1436-6207
- Subject:
- World Health Organization; children; cities; correlation; diet; drinking water; equations; iodine; iodized salt; linear models; public health; villages; China
- Abstract:
- ... PURPOSE: Excess iodine in drinking water has emerged as a public health issue in China. This study assesses the effectiveness of removing iodized salt on reducing the iodine excess in populations living in high-iodine areas and also to identify the threshold value for safe levels of iodine in water. METHODS: Twelve villages from 5 cities of Hebei Province with iodine content in drinking water rang ...
- DOI:
- 10.1007/s00394-014-0767-z
-
http://dx.doi.org/10.1007/s00394-014-0767-z
- Author:
- Mohammadifard, Noushin; Yazdekhasti, Narges; Stangl, Gabriele I.; Sarrafzadegan, Nizal
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 925-931
- ISSN:
- 1436-6207
- Subject:
- adults; almonds; cross-sectional studies; gender; hazelnuts; heart; men; models; nutritional behavior; obesity; odds ratio; pistachios; questionnaires; regression analysis; risk; seeds; sunflower seed; walnuts; women; Iran
- Abstract:
- ... PURPOSE: Recently, controversies have arisen concerning the association between nut intake and obesity. This study was performed to investigate the relationship between nut consumption and obesity among Iranian adults. METHODS: In a cross-sectional survey, 9,660 randomly chosen adults aged ≥19 years were selected based on gender, age and their settlement distributions in three districts of central ...
- DOI:
- 10.1007/s00394-014-0769-x
-
http://dx.doi.org/10.1007/s00394-014-0769-x
- Author:
- Liu, Xiujuan; Pan, Shifeng; Li, Xiao; Sun, Qinwei; Yang, Xiaojing; Zhao, Ruqian
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 971-979
- ISSN:
- 1436-6207
- Subject:
- Meishan; Western blotting; amino acids; body weight; free amino acids; lactation; longissimus muscle; low protein diet; males; messenger RNA; mitogen-activated protein kinase; myostatin; piglets; pregnancy; progeny; protein content; protein synthesis; quantitative polymerase chain reaction; receptors; reverse transcriptase polymerase chain reaction; skeletal muscle; sows; weaning
- Abstract:
- ... PURPOSE: We tested the hypothesis that maternal low-protein (LP) diet during gestation and lactation can program myostatin (MSTN) signaling and protein synthesis in skeletal muscle of offspring at weaning stage (35 days). METHODS: Fourteen Meishan sows were fed either LP or standard-protein diets throughout gestation and lactation, male offspring piglets were killed at weaning stage and longissimu ...
- DOI:
- 10.1007/s00394-014-0773-1
-
http://dx.doi.org/10.1007/s00394-014-0773-1
- Author:
- Svelander, Cecilia; Gabrielsson, Britt G.; Almgren, Annette; Gottfries, Johan; Olsson, Johan; Undeland, Ingrid; Sandberg, Ann-Sofie
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 945-958
- ISSN:
- 1436-6207
- Subject:
- blood serum; body mass index; cholesterol; cross-over studies; diet; fatty acid composition; herring; high density lipoprotein; insulin; low density lipoprotein; men; minced beef; omega-3 fatty acids; overweight; polyunsaturated fatty acids; sugars; triacylglycerols; very low density lipoprotein; vitamin D
- Abstract:
- ... PURPOSE: The aim was to compare postprandial lipid, insulin and vitamin D responses after consumption of three otherwise identical meals served either with baked herring, pickled herring or with baked, minced beef. METHODS: Seventeen healthy, overweight men (mean age 58 years, BMI 26.4–29.5 kg/m²) consumed standardized lunches together with baked herring, pickled herring or baked, minced beef on t ...
- DOI:
- 10.1007/s00394-014-0771-3
-
http://dx.doi.org/10.1007/s00394-014-0771-3
- Author:
- Onitake, Toshiko; Ueno, Yoshitaka; Tanaka, Shinji; Sagami, Shintaro; Hayashi, Ryohei; Nagai, Kenta; Hide, Michihiro; Chayama, Kazuaki
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 959-969
- ISSN:
- 1436-6207
- Subject:
- T-lymphocytes; animal models; bioactive properties; body weight changes; colitis; colon; enzyme-linked immunosorbent assay; flow cytometry; food safety; hepatocytes; immune response; inflammation; interferon-gamma; interleukin-13; interleukin-4; konjac mannan; mice; oral administration; traditional foods; tumor necrosis factor-alpha
- Abstract:
- ... PURPOSE: Pulverized konjac glucomannan (PKGM) is a natural biologically active compound extracted from konjac, a Japanese traditional food. In the present study, we investigated the role of PKGM in intestinal immunity in a mouse model of oxazolone (OXA)-induced colitis. METHODS: C57BL/6(B6) mice were fed PKGM or control food from 2 weeks before the induction of OXA colitis. Body weight change, col ...
- DOI:
- 10.1007/s00394-014-0772-2
-
http://dx.doi.org/10.1007/s00394-014-0772-2
- Author:
- Martín-Pozuelo, Gala; Navarro-González, Inmaculada; González-Barrio, Rocío; Santaella, Marina; García-Alonso, Javier; Hidalgo, Nieves; Gómez-Gallego, Carlos; Ros, Gaspar; Periago, María Jesús
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 933-944
- ISSN:
- 1436-6207
- Subject:
- absorption; adults; alanine transaminase; antioxidants; aspartate transaminase; beta oxidation; biomarkers; fatty acids; fatty liver; feces; gene overexpression; genes; high density lipoprotein; high fat diet; hydrolysis; hyperlipidemia; inflammation; liver; low density lipoprotein; lycopene; males; metabolites; oxidation; oxidative stress; rats; tomato juice; tomatoes; triacylglycerols; urine
- Abstract:
- ... PURPOSE: Tomato products are a dietary source of natural antioxidants, especially lycopene, which accumulates in the liver, where it exerts biological effects. Taking into consideration this fact, the aim of the present study was to ascertain the effect of tomato consumption on biomarkers and gene expression related to lipid metabolism in rats with induced steatosis. METHODS: Adult male Sprague–Da ...
- DOI:
- 10.1007/s00394-014-0770-4
-
http://dx.doi.org/10.1007/s00394-014-0770-4
- Author:
- Young, Hayley; Benton, David
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 1013-1020
- ISSN:
- 1436-6207
- Subject:
- breakfast; children; cognition; emotions; energy; foods; glucose; glycemic index; ingestion; isomaltulose; memory; nutrients; school breakfast
- Abstract:
- ... PURPOSE: Although previous research has associated the glycaemic load (GL) of a meal with cognitive functioning, typically the macro-nutrient composition of the meals has differed, raising a question as to whether the response was to GL or to the energy, nutrients or particular foods consumed. Therefore, the present study contrasted two breakfasts that offered identical levels of energy and macro- ...
- DOI:
- 10.1007/s00394-014-0779-8
- PubMed:
- 25311061
- PubMed Central:
- PMC4540784
-
http://dx.doi.org/10.1007/s00394-014-0779-8
- Author:
- Zanini, Barbara; Villanacci, Vincenzo; De Leo, Luigina; Lanzini, Alberto
- Source:
- European journal of nutrition 2015 v.54 no.6 pp. 1027-1029
- ISSN:
- 1436-6207
- Subject:
- Triticum monococcum; antibodies; biopsy; biscuits; celiac disease; dermatitis; epitopes; gastrointestinal system; gluten; gluten-free diet; patients; questionnaires; remission; serology; toxicity; wheat
- Abstract:
- ... BACKGROUND AND AIMS: To assess safety of prolonged daily administration of Triticum monococcum (Tm) using clinical, serological and histological criteria. Tm is an ancient wheat suitable for production of palatable baked goods that contains gluten devoid of strongly immunostimulatory epitopes and potentially safe for celiac disease (CD) patients as suggested by in vitro and ex vivo studies. METHOD ...
- DOI:
- 10.1007/s00394-015-0892-3
-
http://dx.doi.org/10.1007/s00394-015-0892-3