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- Tomaszewska, Ewa; Winiarska-Mieczan, Anna; Dobrowolski, Piotr
- Experimental and toxicologic pathology 2015 v.67 no.5-6 pp. 331-339
- adolescents; alanine transaminase; apoptosis; aspartate transaminase; cadmium; cell proliferation; chronic exposure; diet; green tea; hemoglobin; hepatocytes; humans; innervation; iron; jejunum; lead; liver; mucosa; necrosis; protective effect; rats; toxicity; white tea
- ... Rats were used to check whether regular consumption of black, red, or white tea would have a protective effect similar to the action of green tea on the intestine and liver in the case of exposure to Cd and Pb within the limits of human environmental exposure to these elements. Rats at the age of 6 weeks were divided into the control and four groups supplemented with green (GT), black (BT), red (R ...
- Tsuji, Takao; Itoh, Masayuki; Kikuchi, Ryota; Uruma, Tomonori; Watanabe, Hidehiro; Yamaguchi, Kazuhiro; Nakamura, Hiroyuki; Aoshiba, Kazutetsu
- Experimental and toxicologic pathology 2015 v.67 no.5-6 pp. 355-360
- adverse effects; carcinogenesis; cell proliferation; chronic exposure; epithelium; fibrosis; fluorescent antibody technique; genotoxicity; histopathology; inflammation; interleukin-6; intraperitoneal injection; lungs; macrophages; males; mice; mutagenicity; parenchyma (animal tissue); pulmonary emphysema; researchers; teratogenicity
- ... Incorporation of 5-bromo-2′-deoxyuridine (BrdU) into proliferating cells has been used to label dividing cells in many tissues. Although BrdU has been shown to be genotoxic, teratogenic and mutagenic, such adverse effects have largely been ignored by researchers. We determined whether long-term BrdU exposure causes any histopathological changes in the lungs of mice. Eight-week-old male C57/BL6J mi ...