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- Federico, Rodolfo, et al. Show all 8 Authors
- FEBS journal 2011 v.278 no.5 pp. 809-821
- Zea mays; active sites; carbon; corn; databases; enzyme substrates; enzymes; mutants; mutation; oxidation; redox potential; spermidine; spermine
- ... Polyamine oxidases are FAD-dependent enzymes catalyzing the oxidation of polyamines at the secondary amino groups. Zea mays PAO (ZmPAO) oxidizes the carbon on the endo-side of the N5-nitrogen of spermidine (Spd) and spermine (Spm). The structure of ZmPAO revealed that the active site is formed by a catalytic tunnel in which the N5 atom of FAD lies in close proximity to the K300 side chain, the onl ...