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- Wu, Ying-Li, et al. Show all 9 Authors
- FEBS letters 2011 v.585 no.2 pp. 375-380
- RNA; binding sites; gel electrophoresis; gene expression regulation; genes; interferons; leukemia; luciferase; retinoic acid
- ... RIG-G is a retinoic acid- or interferon-induced gene with potential anti-proliferation function. However, the mechanism underlying ATRA-induced RIG-G induction is not completely understood. Here, we demonstrate that ATRA up-regulates the expression of PU.1, which in turn directly binds to the promoter and increases the expression of RIG-G gene. Luciferase reporter assay and electrophoretic mobilit ...