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- Nakayasu, Chihaya, et al. Show all 5 Authors
- Fish & shellfish immunology 2013 v.35 no.5 pp. 1591-1597
- Paralichthys olivaceus; Vibrio anguillarum; adaptive immunity; antigens; epithelial cells; flounder; gene expression regulation; gills; immune response; immunohistochemistry; inflammation; interleukin-6; interleukin-8; serotypes; tumor necrosis factor-alpha
- ... The mucosal surfaces of fish allow for the introduction of foreign substances, including antigens, from the surrounding environment. In this study, uptake of Vibrio anguillarum J-O-3 serotype bacterin by Japanese flounder, and the subsequent immune responses were investigated. Immunohistochemistry revealed that the bacterin was taken up through the epithelial cells of gills. The transcription leve ...