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- Shin, Younhee, et al. Show all 6 Authors
- Fish & shellfish immunology 2017 v.62 pp. 276-290
- Oplegnathus fasciatus; Toll-like receptor 5; binding sites; bream; coevolution; cytokines; exons; flagellin; genes; gills; introns; kidneys; leucine; liver; luciferase; messenger RNA; protein structure; quantitative polymerase chain reaction; tissues; transcription factor NF-kappa B
- ... Toll-like receptor 5 (TLR5) recognizes bacterial flagellin and induces the downstream signaling through the myeloid differentiation primary response gene 88 (MyD88) protein to produce proinflammatory cytokines. In this study, we describe a TLR5 membrane form (OfTLR5M) and its adaptor protein MyD88 (OfMyD88) in rock bream, Oplegnathus fasciatus. Both Oftlr5m (6.7 kb) and Ofmyd88 (3.7 kb) genes disp ...