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You searched for: Journal Fitoterapia Remove constraint Journal: Fitoterapia Publication Year 2016 Remove constraint Publication Year: 2016 Source 2016 v.114 Remove constraint Source: 2016 v.114
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1. Acylphloroglucinols from the leaves of Callistemon viminalis

Author:
Liu, Hong-Xin; Chen, Yu-Chan; Liu, Yuan; Zhang, Wei-Min; Wu, Jie-Wei; Tan, Hai-Bo; Qiu, Sheng-Xiang
Source:
Fitoterapia 2016 v.114 pp. 40-44
ISSN:
0367-326X
Subject:
Callistemon viminalis; anti-infective properties; crops; in vitro studies; leaves; medicinal plants; neoplasm cells; spectral analysis; China
Abstract:
... A phytochemical study on the leaves of Callistemon viminalis, a widely distributed ornamental and medicinal plant of agricultural importance in China, resulted in the isolation of eleven acylphloroglucinols, including six new ones named callistenones F-K (1–6), as well as five known congeners. Their structures were fully characterized using spectral data interpretation for the new structures and c ...
DOI:
10.1016/j.fitote.2016.08.010

2. Anti-inflammatory triterpenes from the apical bud of Gardenia sootepensis

Author:
Youn, Ui Joung; Park, Eun-Jung; Kondratyuk, Tamara P.; Sripisut, Tawanun; Laphookhieo, Surat; Pezzuto, John M.; Chang, Leng Chee
Source:
Fitoterapia 2016 v.114 pp. 92-97
ISSN:
0367-326X
Subject:
Gardenia; chemoprevention; fractionation; inhibitory concentration 50; medicinal plants; methylene chloride; neoplasms; nitric oxide; nuclear magnetic resonance spectroscopy; transcription factor NF-kappa B; triterpenoids; tumor necrosis factor-alpha
Abstract:
... Bioassay-guided fractionation of the dichloromethane extract from the apical bud of Gardenia sootepenesis Hutch. (Rubiaceae) led to the isolation of four new cycloartane triterpenes, sootepins F–I (1–4), along with four known derivatives (5–8). The structures of the new compounds were determined by 1D and 2D NMR experiments and by comparison of the physicochemical data with published values. The i ...
DOI:
10.1016/j.fitote.2016.08.012

3. Brazilian Tabernaemontana genus: Indole alkaloids and phytochemical activities

Author:
Marinho, Flávio F.; Simões, André Olmos; Barcellos, Thiago; Moura, Sidnei
Source:
Fitoterapia 2016 v.114 pp. 127-137
ISSN:
0367-326X
Subject:
Tabernaemontana; bioactive properties; geographical distribution; indole alkaloids; medicinal plants; monoterpenoids; subtropics; Brazil
Abstract:
... The Tabernaemontana genus belongs to the family Apocynaceae comprising about 100 species spread throughout tropical and subtropical regions around the world including Brazil, which contains around 40 species spread all over its territory. Because of the territorial space and climate diversity, these species already identified in Brazil are the largest collection of Tabernaemontana, which are repre ...
DOI:
10.1016/j.fitote.2016.09.002

4. Canangalias C-H, juvenile hormone III analogues from the roots of Cananga latifolia

Author:
Phatchana, Ratchanee; Thongsri, Yordhathai; Yenjai, Chavi
Source:
Fitoterapia 2016 v.114 pp. 45-50
ISSN:
0367-326X
Subject:
Cananga; juvenile hormones; mass spectrometry; medicinal plants; nuclear magnetic resonance spectroscopy; roots; spectral analysis
Abstract:
... Chemical investigation of the roots of Cananga latifolia led to the isolation and purification of thirteen juvenile hormone III analogues. Six new analogues, canangalias C-H (1–6) and a new natural product, (2E,6E,10R)-10-acetoxy-11-hydroxy-3,7,11-trimethyldodeca-2,6-dienoic acid methyl ester (7), were isolated. In addition, six known juvenile hormone III analogues were isolated. Their structures ...
DOI:
10.1016/j.fitote.2016.08.018

5. Chemical structures, production and enzymatic transformations of sapogenins and saponins from Centella asiatica (L.) Urban

Author:
Azerad, Robert
Source:
Fitoterapia 2016 v.114 pp. 168-187
ISSN:
0367-326X
Subject:
Centella asiatica; biosynthesis; biotransformation; chemical structure; humans; medicinal plants; medicinal properties; metabolites; microorganisms; sapogenins; surveys; triterpenoid saponins
Abstract:
... Centella asiatica (L.) Urban is a medicinal herb traditionally used in Asiatic countries for its multiple therapeutic properties, essentially due to its accumulation of specific pentacylic triterpenoid saponins, mainly asiaticoside and madecassoside and the corresponding sapogenins. This review summarizes the updated knowledge about the chemical structures of about forty centelloids, found as mino ...
DOI:
10.1016/j.fitote.2016.07.011

6. Clerodens E–J, antibacterial caffeic acid derivatives from the aerial part of Clerodendranthus spicatus

Author:
Li, Qing; He, Ying-Na; Shi, Xiao-Wei; Kang, Li-Ying; Niu, Li-Ying; Wang, Xin-Guo; Feng, Wei
Source:
Fitoterapia 2016 v.114 pp. 110-114
ISSN:
0367-326X
Subject:
Orthosiphon aristatus; aerial parts; antibacterial properties; bacteria; caffeic acid; drug resistance; medicinal plants; nuclear magnetic resonance spectroscopy
Abstract:
... Six new caffeic acid derivatives, Clerodens E–J (1–6) were isolated from the aerial part of Clerodendranthus spicatus. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. Compound 1 showed moderate antibacterial activities against drug-resistant strains of bacteria in vitro. ...
DOI:
10.1016/j.fitote.2016.08.021

7. Colossolactone H, a new Ganoderma triterpenoid exhibits cytotoxicity and potentiates drug efficacy of gefitinib in lung cancer

Author:
Chen, Su-Yu; Chang, Chao-Lin; Chen, Teng-Hai; Chang, Ya-Wen; Lin, Shwu-Bin
Source:
Fitoterapia 2016 v.114 pp. 81-91
ISSN:
0367-326X
Subject:
DNA damage; Ganoderma; apoptosis; cell cycle; cell growth; cytotoxicity; drugs; fruiting bodies; gene expression regulation; genes; growth retardation; lung neoplasms; medicinal fungi; medicinal plants; mice; neoplasm cells; oxidation; reactive oxygen species; therapeutics; triterpenoids; tumor suppressor protein p53
Abstract:
... Three pentacyclic triterpene dilactones were isolated from the fruiting bodies of Ganoderma colossum, a medicinal mushroom. Colossolactone H (colo H) as a new compound and the most cytotoxic among the isolates was studied for its anticancer mechanism and the potential use in cancer therapy. Gene expression profiling analysis indicated that treatment of lung cancer cells with colo H caused upregula ...
DOI:
10.1016/j.fitote.2016.08.015

8. Compounds from Polyphaga plancyi and their inhibitory activities against JAK3 and DDR1 kinases

Author:
Zhu, Hong-Jie; Yan, Yong-Ming; Tu, Zheng-Chao; Luo, Jin-Feng; Liang, Rui; Yang, Tong-Hua; Cheng, Yong-Xian; Wang, Shu-Mei
Source:
Fitoterapia 2016 v.114 pp. 163-167
ISSN:
0367-326X
Subject:
enantiomers; high performance liquid chromatography; inhibitory concentration 50; medicinal plants; nuclear magnetic resonance spectroscopy; phosphotransferases (kinases)
Abstract:
... Plancyamides A (1) and B (3), plancypyrazine A (2), and plancyols A (4) and B (5), five new compounds (1–5), and three known ones (6–8), were isolated from the whole bodies of Polyphaga plancyi Bolivar. Their structures were elucidated by a combination of spectroscopic analyses including 1D and 2D NMR, and HRESIMS. Among them, compound 3 is racemic, chiral HPLC separation afforded its respective e ...
DOI:
10.1016/j.fitote.2016.09.005

9. Eight new eudesmane- and eremophilane-type sesquiterpenoids from Atractylodes lancea

Author:
Xu, Kuo; Feng, Zi-Ming; Yang, Ya-Nan; Jiang, Jian-Shuang; Zhang, Pei-Cheng
Source:
Fitoterapia 2016 v.114 pp. 115-121
ISSN:
0367-326X
Subject:
Atractylodes lancea; acetaminophen; circular dichroism spectroscopy; hepatoprotective effect; human cell lines; medicinal plants; rhizomes; sesquiterpenoids
Abstract:
... Phytochemical and pharmacological study on the rhizomes of Atractylodes lancea led to the identification of twenty-one compounds: six new eudesmane-type sesquiterpenoids (1–6), two new eremophilane-type sesquiterpenoids (7, 8), and thirteen known compounds (9–21). These new compounds were elucidated using extensive spectroscopic analyses with experimental and calculated electronic circular dichroi ...
DOI:
10.1016/j.fitote.2016.08.017

10. (E)-9-oxooctadec-10-en-12-ynoic acid from Ixora brachiata Roxb. increases glucose uptake in L6 myotubes by activating the PI3K pathway

Author:
Thakkar, Chandni S.; Kshirsagar, Rajendra R.; Naik, Vinayak R.; Ghosh, Asit Ranjan; Vijayakumar, V.; Saklani, Arvind; Kulkarni-Almeida, Asha A.
Source:
Fitoterapia 2016 v.114 pp. 26-33
ISSN:
0367-326X
Subject:
Ixora; dose response; fractionation; glucose; glucose transporters; glycemic effect; insulin; median effective concentration; medicinal plants; myotubes; petroleum; phosphatidylinositol 3-kinase; phosphorylation; plant extracts; plasma membrane
Abstract:
... In an attempt to discover new scaffolds for anti-diabetic activity from plants, we screened extracts from Ixora brachiata Roxb. for their effect on glucose uptake in L6 myotubes. The petroleum (PE) extract of the plant showed a significant increase in insulin stimulated glucose uptake by L6 myotubes. The bioactivity guided fractionation of the crude extract yielded a compound (E)-9-oxooctadec-10-e ...
DOI:
10.1016/j.fitote.2016.08.004

11. Erecricins A–E, prenylated acylphloroglucinols from the roots of Hypericum erectum

Author:
Lu, Shuangxin; Tanaka, Naonobu; Tatano, Yutaka; Kashiwada, Yoshiki
Source:
Fitoterapia 2016 v.114 pp. 188-193
ISSN:
0367-326X
Subject:
Hypericum erectum; anti-infective properties; chemical structure; medicinal plants; roots; spectral analysis
Abstract:
... Six new prenylated acylphloroglucinols, erecricins A–E (1–5) and adotogirin (6), were isolated from the roots of Hypericum erectum (Hypericaceae). Their structures were assigned on the basis of spectroscopic evidences. Erecricins A–E (1–5) are bicyclic prenylated acylphloroglucinols possessing a chromane or a chromene skeleton. Adotogirin (6) is a simple achylphloroglucinol with an O-geranyl moiet ...
DOI:
10.1016/j.fitote.2016.08.014

12. Flavoniods from aerial parts of Astragalus hoantchy

Author:
Guo, Kai; He, Xiaofeng; Zhang, Yanping; Li, Xiuzhuang; Yan, Zhiqiang; Pan, Le; Qin, Bo
Source:
Fitoterapia 2016 v.114 pp. 34-39
ISSN:
0367-326X
Subject:
Alternaria solani; Astragalus; aerial parts; antifungal properties; circular dichroism spectroscopy; flavonoids; inhibitory concentration 50; medicinal plants; nuclear magnetic resonance spectroscopy; plant pathogenic fungi
Abstract:
... Four new flavonoids, astragaisoflavans A–D (1–4), along with thirteen known ones (5–17) were isolated from the aerial parts of Astragalus hoantchy. Their structures were established by the extensive spectroscopic analyses including one- and two-dimensional NMR, HRESIMS, IR, and UV results. The absolute configurations of 1–4 were deduced based on circular dichroism. Compounds 1–3 all possessed a ra ...
DOI:
10.1016/j.fitote.2016.08.009

13. Flavonoids from Caragana pruinosa roots

Author:
Peng, Wei; Wang, Liang; Qiu, Xu-Hui; Jiang, Yi-Ping; Pan, Lan; Jia, Xiao-Guang; Qin, Lu-Ping; Zheng, Cheng-Jian
Source:
Fitoterapia 2016 v.114 pp. 105-109
ISSN:
0367-326X
Subject:
Caragana; chalcone; inhibitory concentration 50; macrophages; medicinal plants; nitric oxide; nuclear magnetic resonance spectroscopy; roots
Abstract:
... A new pterocarpan derivative, pruinosanone D (1), a new isoflavonoid, pruinosanone E (2), and a new chalcone, pruinosanone F (3), were isolated from Caragana pruinosa roots, along with four known analogues (4–7), identified as 2,4-dihydroxy-3′-methoxy-4′-ethoxychalcone, 7,4-dihydroxyflavanone, butin and scutellaprostin C, respectively. Their structures were elucidated by detailed analyses of NMR, ...
DOI:
10.1016/j.fitote.2016.08.020

14. Herbal extracts, lichens and biomolecules as natural photo-protection alternatives to synthetic UV filters. A systematic review

Author:
Radice, Matteo; Manfredini, Stefano; Ziosi, Paola; Dissette, Valeria; Buso, Piergiacomo; Fallacara, Arianna; Vertuani, Silvia
Source:
Fitoterapia 2016 v.114 pp. 144-162
ISSN:
0367-326X
Subject:
DNA; UV filters; carcinogenesis; databases; human health; lichens; markets; medicinal plants; plant extracts; sunscreens; synergism; systematic review; toxicology; ultraviolet radiation
Abstract:
... Besides the unquestionable positive effects of solar exposure for human health, UV rays have been widely investigated for toxicology aspects related to excessive UVB and UVA doses, which involve sunburns, skin aging, DNA skin damage and tumorigenesis. At present, synthetic and mineral sunscreens are used to protect against these damages but several natural molecules can provide UV protection, incl ...
DOI:
10.1016/j.fitote.2016.09.003

15. 1H NMR spectroscopy-guided isolation of new sucrose esters from Physalis alkekengi var. franchetii and their antibacterial activity

Author:
Zhang, Chuan-Yang; Luo, Jian-Guang; Liu, Rui-Huan; Lin, Ru; Yang, Ming-Hua; Kong, Ling-Yi
Source:
Fitoterapia 2016 v.114 pp. 138-143
ISSN:
0367-326X
Subject:
Bacillus subtilis; Escherichia coli; Physalis alkekengi var. franchetii; Pseudomonas aeruginosa; Staphylococcus aureus; aerial parts; antibacterial properties; drugs; ingredients; medicinal plants; minimum inhibitory concentration; nuclear magnetic resonance spectroscopy; sucrose esters
Abstract:
... Ten new sucrose esters, physakengoses A–J (1−10), were isolated from the aerial parts of Physalis alkekengi var. franchetii under the guidance of 1H NMR spectroscopy. Their structures were determined by spectroscopic analyses (HRESIMS, 1D and 2D NMR, and ESIMS) and chemical methods. These new compounds were tested for antibacterial activities against Staphylococcus aureus, Bacillus subtilis, Pseud ...
DOI:
10.1016/j.fitote.2016.09.007

16. Immunochromatographic strip assay for detection of bioactive Ganoderma triterpenoid, ganoderic acid A in Ganoderma lingzhi

Author:
Sakamoto, Seiichi; Kikkawa, Nao; Kohno, Toshitaka; Shimizu, Kuniyoshi; Tanaka, Hiroyuki; Morimoto, Satoshi
Source:
Fitoterapia 2016 v.114 pp. 51-55
ISSN:
0367-326X
Subject:
Ganoderma; detection limit; dipping; enzyme-linked immunosorbent assay; ganoderic acid; immunoaffinity chromatography; medicinal fungi; medicinal plants; medicinal properties; monoclonal antibodies; mushrooms; nanogold; rapid methods; China
Abstract:
... Ganoderic acid A (GAA) is one of the major Ganoderma triterpenes produced by medicinal mushroom belonging to the genus Ganoderma (Ganodermataceae). Due to its interesting pharmacological activities, Ganoderma species have been traditionally used in China for the treatment of various diseases. Herein, we developed a colloidal gold-based immunochromatographic strip assay (ICA) for the rapid detectio ...
DOI:
10.1016/j.fitote.2016.08.016

17. In vitro modulation of inflammatory target gene expression by a polyphenol-enriched fraction of rose oil distillation waste water

Author:
Wedler, Jonas; Weston, Anna; Rausenberger, Julia; Butterweck, Veronika
Source:
Fitoterapia 2016 v.114 pp. 56-62
ISSN:
0367-326X
Subject:
Rosa damascena; biomarkers; cell proliferation; chemokine CCL5; ellagic acid; enzyme-linked immunosorbent assay; flowers; gene expression; groundwater; inflammation; interleukin-1beta; interleukin-6; interleukin-8; keratinocytes; medicinal plants; oils; polyphenols; protein secretion; reverse transcriptase polymerase chain reaction; steam distillation; surface water; tumor necrosis factor-alpha; wastewater; water pollution
Abstract:
... Classical production of rose oil is based on water steam distillation from the flowers of Rosa damascena. During this process, large quantities of waste water accrue which are discharged to the environment, causing severe pollution of both, groundwater and surface water due to a high content of polyphenols. We recently developed a strategy to purify the waste water into a polyphenol-depleted and a ...
DOI:
10.1016/j.fitote.2016.08.019

18. Lignans from the stem bark of Syringa pinnatifolia

Author:
Su, Guozhu; Zhang, Ruifei; Yang, Xinyao; Bai, Ruifeng; Yin, Xu; Gao, Xiaoli; Li, Li; Tu, Pengfei; Chai, Xingyun
Source:
Fitoterapia 2016 v.114 pp. 63-68
ISSN:
0367-326X
Subject:
Syringa; X-ray diffraction; bark; circular dichroism spectroscopy; glucose; hydrolysis; inhibitory concentration 50; interleukin-6; lignans; macrophages; medicinal plants; neuroprotective effect; nitric oxide; nuclear magnetic resonance spectroscopy; oxygen; tumor necrosis factor-alpha
Abstract:
... Four new lignans, alashinols A–D (1–4), a new hydrolysis product, alashinols E (5), and seven known analogues were isolated from the stem bark of Syringa pinnatifolia Hemsl. These new lignans were characterized using 1D and 2D NMR and MS data, and their absolute configurations were determined by experimental and calculated electronic circular dichroism and X-ray diffraction analyses. Alashinol B ( ...
DOI:
10.1016/j.fitote.2016.08.011

19. Mechanism of action of herbs and their active constituents used in hair loss treatment

Author:
Herman, Anna; Herman, Andrzej P.
Source:
Fitoterapia 2016 v.114 pp. 18-25
ISSN:
0367-326X
Subject:
alopecia; endothelial nitric oxide synthase; epidermal growth factor; fibroblast growth factor 2; herbs; insulin-like growth factor I; mechanism of action; medicinal plants; prostaglandins; signal transduction; topical application; transforming growth factor beta; vascular endothelial growth factors
Abstract:
... This article discusses the mechanisms via topically applied products containing herbs and their active constituents affect the hair growth process. It was reported that the mechanisms involving (1) insulin-like growth factor-I (IGF-I), (2) vascular endothelial growth factor (VEGF), (3) epidermal growth factor (EGF), (4) fibroblast growth factor 2 (FGF-2), (5) endothelial nitric oxide synthase (eNO ...
DOI:
10.1016/j.fitote.2016.08.008

20. New pregnane and phenolic glycosides from Solenostemma argel

Author:
Ounaissia, Karima; Pertuit, David; Mitaine-Offer, Anne-Claire; Miyamoto, Tomofumi; Tanaka, Chiaki; Delemasure, Stéphanie; Dutartre, Patrick; Smati, Dalila; Lacaille-Dubois, Marie-Aleth
Source:
Fitoterapia 2016 v.114 pp. 98-104
ISSN:
0367-326X
Subject:
aerial parts; antioxidant activity; cytotoxicity; glycosides; humans; interleukin-1beta; medicinal plants; mononuclear leukocytes; neoplasm cells; nuclear magnetic resonance spectroscopy; roots
Abstract:
... From the aerial parts, pericarps and roots of Solenostemma argel, three new pregnane glycosides (1–3) with two known ones and a new phenolic glycoside (4) have been isolated. Their structures were established by extensive 1D – and 2D NMR and mass spectroscopic analysis. The cytotoxicity of all compounds was evaluated against two human tumor cell lines (SW 480, MCF-7), but none of them was active i ...
DOI:
10.1016/j.fitote.2016.08.002