Jump to Main Content
- Li, Shuyi, et al. Show all 7 Authors
- Food & function 2018 v.9 no.11 pp. 5778-5790
- Pseudocydonia sinensis; Western blotting; blood serum; creatinine; ethyl acetate; excretion; fruit extracts; glutathione peroxidase; gout; histopathology; hyperuricemia; inflammation; kidneys; liver; mechanism of action; mice; potassium; protein content; protein synthesis; renal function; superoxide dismutase; transporters; uric acid
- ... Clinically, Chaenomeles sinensis (Thouin) Koehne (C. sinensis) has been used to treat hyperuricemia and gout. However, the exact mechanism of action is still unknown. In the present study, the ethyl acetate fraction of C. sinensis fruit extract (CSF-E) was separated. Potassium oxonate (PO)-induced hyperuricemic mice and normal mice were administered with CSF-E at 60, 120 and 180 mg kg⁻¹, respectiv ...
- Li, Shuyi, et al. Show all 6 Authors
- Food & function 2018 v.9 no.9 pp. 4651-4663
- active sites; alpha-amylase; alpha-glucosidase; animal disease models; digestion; epigallocatechin gallate; gluconeogenesis; glucose; green tea; high fat diet; homeostasis; human diseases; hydrolysis; intestinal absorption; lipogenesis; liver; mice; molecular dynamics; noninsulin-dependent diabetes mellitus; obesity; pharmacokinetics; polyphenols; small intestine; starch; therapeutics
- ... As a major component of green tea, (−)-epigallocatechin-3-gallate (EGCG) has attracted interest from scientists owing to its potential to combat a variety of human diseases including abnormal glucose metabolism in obesity and diabetes. This study aims to (1) evaluate the molecular mechanism of EGCG in starch digestion before EGCG absorption; (2) investigate the link between PXR/CAR-mediated phase ...