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- Von Tungeln, Linda S.; Walker, Nigel J.; Olson, Greg R.; Mendoza, Maria C.B.; Felton, Robert P.; Thorn, Brett T.; Marques, M. Matilde; Pogribny, Igor P.; Doerge, Daniel R.; Beland, Frederick A.
- Food and chemical toxicology 2017 v.99 pp. 170-181
- biliary tract; bioassays; body weight; carcinogenicity; dietary exposure; epididymis; foods; humans; hyperplasia; liver; males; mesothelioma; mice; neoplasm cells; rats; risk; risk assessment; testes; toxicology; volatile organic compounds
- ... Furan is a volatile organic chemical that is a contaminant in many common foods. Furan is hepatocarcinogenic in mice and rats; however, the risk to humans from dietary exposure to furan cannot be estimated accurately because the lowest tested dose of furan in a 2-year bioassay in rats gave nearly a 100% incidence of cholangiocarcinoma. To provide bioassay data that can be used in preparing risk as ...
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