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- Song, Ge; Cui, Yi; Han, Zhong-Ji; Xia, Hong-Fei; Ma, Xu
- Food and chemical toxicology 2012 v.50 no.12 pp. 4364-4374
- neural tube defects, etc ; DNA methylation; abnormal development; animal models; apoptosis; arsenic; body weight; chicks; choline; early development; embryo (animal); embryogenesis; metabolism; neurodevelopment; placenta; sodium arsenite; toxicology; viability; Show all 18 Subjects
- ... Arsenic passes through the placenta and accumulates in the neuroepithelium of embryo, whereby inducing congenital malformations such as neural tube defects (NTDs) in animals. Choline (CHO), a methyl-rich nutrient, functions as a methyl donor to participate in methyl group metabolism. Arsenic methylation has been regarded as a detoxification process and choline (CHO) is the major source of methyl-g ...
- Li, Xiao-Di; He, Rong-Rong; Qin, Yang; Tsoi, Bun; Li, Yi-Fang; Ma, Zheng-Lai; Yang, Xuesong; Kurihara, Hiroshi
- Food and chemical toxicology 2012 v.50 no.6 pp. 1848-1853
- neural tube defects, etc ; adults; adverse effects; behavior disorders; brain; caffeine; chickens; embryogenesis; fetal development; gene expression; metabolites; neurodevelopment; neurotransmitters; pregnancy; pregnant women; serotonin; teratogenicity; toxicology; Show all 18 Subjects
- ... The potential harmful effects of caffeine in pregnant women aroused public interests due to its possibility to jeopardize fetal development. Monoamine neurotransmitters are thought to regulate neural development processes through maternal–fetal interactions, which may have long term impact on mental and behavioral effects. The current study focuses on investigating the effects of caffeine on the m ...