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- Gardner, H.W.; Crawford, C.G.; MacGregor, J.T.
- Food and chemical toxicology 1983 v.21 no.2 pp. 175
- lipid peroxidation, etc ; linoleic acid; hydrogen peroxide; oxidation; isomers; epoxides; fatty acid esters; mutagenicity; rats; animal models; liver; oxidative stress; pyrene (hydrocarbon); structure-activity relationships; dietary fat; Show all 15 Subjects
- ... Five isomeric epoxyhydroxyene and epoxyoxoene fatty esters derived from homolytic decomposition of linoleic acid hydroperoxide were tested for mutagenicity by the 'Ames' top-agar incorporation method using S-9 mix derived from livers of male rats pretreated with Aroclor 1254. The epoxide fatty esters tested - methyl r409w1 =trans-12,13-epoxy-threo-11-hydroxy-cis(trans)-9-octadeceno ate trans-12,13 ...