You searched for:
Journal name
Genes & genomics
Remove constraint Journal name: Genes & genomics
Publication year rev
7981-2019
Remove constraint Publication year rev: 7981-2019
Source
2019 v.41 no.10
Remove constraint Source: 2019 v.41 no.10
PubAg
Main content area
Search
11 Search Results
1 - 11 of 11
Search Results
- Author:
- Ilda P. Ribeiro; Joana M. Rodrigues; Alexandra Mascarenhas; Vanessa Marques; Francisco Caramelo; Maria J. Julião; Thomas Liehr; Joana B. Melo; Isabel M. Carreira
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1207-1221
- ISSN:
- 1976-9571
- Subject:
- GATA transcription factors; cell culture; cell lines; chromosome translocation; chromosomes; comparative genomic hybridization; epigenetics; fluorescence in situ hybridization; genes; genomics; head and neck neoplasms; humans; karyotyping; methylation; models; neoplasm cells; squamous cell carcinoma; therapeutics
- Abstract:
- ... BACKGROUND: Head and neck squamous cell carcinoma cell lines are useful preclinical models to understand the molecular processes underlying the development of such tumors, and to establish targeted therapies. OBJECTIVE: We performed a comprehensive (cyto)genomic and epigenetic characterization of three new established primary human head and neck squamous cell carcinoma cultures and an established, ...
- DOI:
- 10.1007/s13258-019-00850-6
- https://doi.org/10.1007/s13258-019-00850-6
- Author:
- Guoling Li; Zonglian Pan; Shichen Gao; Yuyang He; Qiaoyu Xia; Yan Jin; Huipeng Yao
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1173-1181
- ISSN:
- 1976-9571
- Subject:
- DNA; Porphyra; chloroplast genes; chloroplast genome; codon usage; computer software; genetic engineering; models; mutation; natural selection; nuclear genome; photosystem I; prediction
- Abstract:
- ... BACKGROUND: Synonymous codon usage bias is noticed in the genome of every organism, influenced by mutation pressure and natural selection. The analysis of codon usage pattern in Porphyra umbilicalis chloroplast genome are inferred while previous study focused on codon bias in nuclear genome. OBJECTIVE: To develop a better understanding of the factors affecting synonymous codon usage, codon usage p ...
- DOI:
- 10.1007/s13258-019-00847-1
- https://doi.org/10.1007/s13258-019-00847-1
- Author:
- Yonghong Xie; Yan Feng; Qi Chen; Feike Zhao; Shuijuan Zhou; Ying Ding; Xianliang Song; Ping Li; Baohua Wang
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1135-1145
- ISSN:
- 1976-9571
- Subject:
- Zea mays; algorithms; alkaline soils; computer software; corn; genes; genetic distance; genetic improvement; genome-wide association study; genotyping; inbred lines; loci; plant breeding; plant height; quantitative polymerase chain reaction; quantitative trait loci; saline soils; salt tolerance; single nucleotide polymorphism
- Abstract:
- ... BACKGROUND: Salt-tolerant breeding of maize has great significance to the development and utilization of saline–alkaline soil and the maintenance of grain security. Genome-wide association study (GWAS) has been widely used in maize genetics and breeding. OBJECTIVE: To discover new salt-tolerant genes in maize by association analysis, which can provide technical supports for the innovation and gene ...
- DOI:
- 10.1007/s13258-019-00842-6
- https://doi.org/10.1007/s13258-019-00842-6
- Author:
- Rui Su; Ping Sun; Dianhong Zhang; Wei Xiao; Chun Feng; Liang Zhong
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1223-1231
- ISSN:
- 1976-9571
- Subject:
- CXCR5 receptor; Western blotting; anesthesia; apoptosis; bioluminescence assay; cognition; crossing; inflammation; interleukin-1beta; interleukin-6; messenger RNA; microRNA; neurodegenerative diseases; neurons; neuroprotective effect; non-specific serine/threonine protein kinase; pathogenesis; phosphatidylinositol 3-kinase; protein synthesis; quantitative polymerase chain reaction; rats; reverse transcriptase polymerase chain reaction; sevoflurane; signal transduction; staining; swimming; tumor necrosis factor-alpha
- Abstract:
- ... BACKGROUND: Postoperative cognitive dysfunction (POCD) is a neurodegenerative disorder with impairment of cognition. Sevoflurane anesthesia has been found to lead to CD and microRNAs (miRNAs) were reported to affect cognitive function. This study investigates the neuroprotective effect against sevoflurane anesthesia-induced CD. METHODS: HE staining was used to detect the pathological change of hip ...
- DOI:
- 10.1007/s13258-019-00851-5
- https://doi.org/10.1007/s13258-019-00851-5
- Author:
- Zhi Chen; Shuangfeng Chu; Xin Xu; Jingyi Jiang; Wenqiang Wang; Hongliang Shen; Mingxun Li; Huimin Zhang; Yongjiang Mao; Zhangping Yang
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1147-1163
- ISSN:
- 1976-9571
- Subject:
- DNA methylation; Simmental; beef cattle; epigenetics; fatty acid composition; gene expression regulation; genes; loci; longissimus muscle; meat production; meat quality; muscle development; pH; phenotype; sequence analysis
- Abstract:
- ... BACKGROUND: As cattle represent one of the most important livestock species for meat production, control of muscle development in regards to quality is an important research focus. OBJECTIVES: In this study, the phenotypic quality traits and its associations with DNA methylation levels of the longissimus muscle in two cattle breeds were studied. METHODS: The pH value, water loss rate, fat and prot ...
- DOI:
- 10.1007/s13258-019-00844-4
- https://doi.org/10.1007/s13258-019-00844-4
- Author:
- Xiangyu Zhang; Cunyuan Li; Xiaoyue Li; Zhijin Liu; Wei Ni; Yang Cao; Yang Yao; Esenbay Islamov; Junchang Wei; Xiaoxu Hou; Shengwei Hu
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1165-1171
- ISSN:
- 1976-9571
- Subject:
- body length; carcass characteristics; chi-square distribution; early development; genes; genetic variation; genotype; loci; polymerase chain reaction; selective breeding; sheep; single nucleotide polymorphism; vertebrae
- Abstract:
- ... INTRODUCTION: The vertebral number is an economically significant trait, which is associated with body length and carcass traits. Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1) is a member of the nuclear receptor superfamily and it plays an important role in the early development of embryos. OBJECTIVES: The NR6A1 gene was considered as an important candidate for influence vertebrae number ...
- DOI:
- 10.1007/s13258-019-00843-5
- https://doi.org/10.1007/s13258-019-00843-5
- Author:
- Van Thai Than; Ha Thi Thanh Tran; Duc Viet Ly; Hoang Vu Dang; Minh Nam Nguyen; Anh Duc Truong
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1195-1206
- ISSN:
- 1976-9571
- Subject:
- B-cell lymphoma; apoptosis; bioinformatics; chickens; cluster analysis; cytokines; developmental stages; embryo (animal); gene expression regulation; genes; immune response; pathogens; phylogeny; sequence analysis; tissues; transcription factor NF-kappa B
- Abstract:
- ... BACKGROUND: B cell lymphoma (BCL) families play an important role in apoptosis as a growth factor, cell death programming, cytokine expression and immune-related genes expression. OBJECTIVES: In this study, to investigate the roles of BCLs, we performed genome-wide identification, expression and functional analyses of the BCL family in chicken. METHODS: Chicken BCLs genes were identified and analy ...
- DOI:
- 10.1007/s13258-019-00849-z
- https://doi.org/10.1007/s13258-019-00849-z
- Author:
- Yong-Soo Park; Songmi Kim; Dong-Guk Park; Dong Hee Kim; Kyeong-Wook Yoon; Wonseok Shin; Kyudong Han
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1233-1240
- ISSN:
- 1976-9571
- Subject:
- DNA libraries; RNA; RNA libraries; cost effectiveness; high-throughput nucleotide sequencing; transcriptome; transcriptomics
- Abstract:
- ... BACKGROUND: The emergence of next-generation sequencing (NGS) technologies has made a tremendous contribution to the deciphering and significance of transcriptome analysis in biological fields. Since the advent of NGS technology in 2007, Illumina, Inc. has provided one of the most widely used sequencing platforms for NGS analysis. OBJECTIVE: Although reagents and protocols provided by Illumina are ...
- DOI:
- 10.1007/s13258-019-00853-3
- https://doi.org/10.1007/s13258-019-00853-3
- Author:
- Supriya Jagga; Ashish Ranjan Sharma; Manojit Bhattacharya; Chiranjib Chakraborty; Sang-Soo Lee
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1113-1125
- ISSN:
- 1976-9571
- Subject:
- bone resorption; chondrocytes; cytokines; fibroblasts; genes; inflammation; macrophages; monocytes; osteoblasts; patients; receptors; single nucleotide polymorphism; variance
- Abstract:
- ... Wear debris-induced inflammatory osteolysis remains a significant limiting factor for implant replacement surgeries. Hence, a comprehensive understanding of the complex network of cellular and molecular signals leading to these inflammatory responses is required. Both macrophages and monocytes have a critical role in the instigation of the inflammatory reaction to wear debris but differ in the ext ...
- DOI:
- 10.1007/s13258-019-00845-3
- https://doi.org/10.1007/s13258-019-00845-3
- Author:
- Jiyeong Shin; Jibom Jung; Won Kim; Jongwoo Jung
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1127-1134
- ISSN:
- 1976-9571
- Subject:
- Hemigrapsus sanguineus; aquatic organisms; crabs; cytochrome-c oxidase; genetic structure; genetic variation; larvae; littoral zone; mitochondria; models; phylogeography; Japan; South Korea; Taiwan
- Abstract:
- ... BACKGROUND: The genetic structure of marine organisms in the East Asian region has long been a subject of interest. Two grapsid crab species, Hemigrapsus penicillatus (De Haan, 1835) and Hemigrapsus sanguineus (De Haan, 1835), are commonly found in the rocky intertidal zones around this region. They are known to spread via larval migration, which makes them an appropriate model species for observi ...
- DOI:
- 10.1007/s13258-019-00831-9
- https://doi.org/10.1007/s13258-019-00831-9
- Author:
- Zhenchao Yang; Zhengyan Wang; Chengcheng Yang; Zhao Yang; Hongquan Li; Yongjun Wu
- Source:
- Genes & genomics 2019 v.41 no.10 pp. 1183-1194
- ISSN:
- 1976-9571
- Subject:
- chlorophyll; corn; crop yield; enzyme activity; gene expression regulation; gene ontology; genes; microRNA; nitrate nitrogen; nitrogen; nitrogen metabolism; peroxidase; physiological response; prediction; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; sequence analysis; superoxide dismutase; transcription factors
- Abstract:
- ... BACKGROUND: Maize is an important crop in the world, nitrogen stress severely reduces maize yield. Although a large number of studies have identified the expression changes of microRNAs (miRNAs) under N stress in several species, the miRNAs expression patterns of N-deficient plants under N resupply remain unclear. OBJECTIVE: The primary objective of this study was to identify miRNAs in response to ...
- DOI:
- 10.1007/s13258-019-00848-0
- https://doi.org/10.1007/s13258-019-00848-0