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- Shin, Ha Youn
- Genes & genomics 2019 v.41 no.3 pp. 257-265
- bioactive properties; chromatin; disease course; gene editing; genes; human diseases; humans; repressor proteins
- ... BACKGROUND: Super-enhancers play critical roles in cell-type specific gene controls and human disease progression. CCCTC-binding factor (CTCF), a transcriptional repressor that insulates the expression of neighboring genes and is involved in chromatin interactions, is frequently present in the boundary regions of or within super-enhancers. However, the structural and functional roles of CTCF in re ...