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- Zhou, Chi, et al. Show all 15 Authors
- Genome biology 2018 v.19 no.1 pp. 80
- RNA; epigenetics; genetic engineering; prediction
- ... A major challenge for effective application of CRISPR systems is to accurately predict the single guide RNA (sgRNA) on-target knockout efficacy and off-target profile, which would facilitate the optimized design of sgRNAs with high sensitivity and specificity. Here we present DeepCRISPR, a comprehensive computational platform to unify sgRNA on-target and off-target site prediction into one framewo ...
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