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- Zainabadi, Kayvan; Jain, Anuja V.; Donovan, Frank X.; Elashoff, David; Rao, Nagesh P.; Murty, Vundavalli V.; Chandrasekharappa, Settara C.; Srivatsan, Eri S.
- Genomics 2014 v.103 pp. 276-287
- chromosome elimination, etc ; African Americans; ancestry; fibroblasts; heterozygosity; homologous recombination; hybrids; linkage disequilibrium; molecular cloning; polymerase chain reaction; sequence analysis; single nucleotide polymorphism; thermodynamics; Show all 13 Subjects
- ... Cloning and sequencing of 5.5kb deletion at chromosome 11q13.1 from the HeLa cells, tumorigenic hybrids and two fibroblast cell lines have revealed homologous recombination between AluSx and AluY resulting in the deletion of intervening sequences. Long-range PCR of the 5.5kb sequence in 494 normal lymphocyte samples showed heterozygous deletion in 28.3% of African-American ancestry samples but onl ...
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