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"Berger, Cedric N."
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Infection and immunity
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- Author:
- Berger, Cedric N., et al. ; Bulgin, Richard; Raymond, Benoit; Garnett, James A.; Frankel, Gad; Crepin, Valerie F.; Arbeloa, Ana; Show all 7 Authors
- Source:
- Infection and immunity 2010 v.78 no.4 pp. 1417-1425
- ISSN:
- 0019-9567
- Subject:
- guanosinetriphosphatase; Salmonella Typhimurium; enterohemorrhagic Escherichia coli; enteropathogenic Escherichia coli; pseudopodia; guanine; signal transduction; type III secretion system; new family; actin; Shigella flexneri; pathogens
- Abstract:
- ... Subversion of Rho family small GTPases, which control actin dynamics, is a common infection strategy used by bacterial pathogens. In particular, Salmonella enterica serovar Typhimurium, Shigella flexneri, enteropathogenic Escherichia coli (EPEC), and enterohemorrhagic Escherichia coli (EHEC) translocate type III secretion system (T3SS) effector proteins to modulate the Rho GTPases RhoA, Cdc42, and ...
- DOI:
- 10.1128/IAI.01250-09
- PubMed:
- 20123714
- PubMed Central:
- PMC2849395
- http://dx.doi.org/10.1128/IAI.01250-09
- Author:
- Berger, Cedric N., et al. ; Hemrajani, Cordula; Marches, Olivier; Wiles, Siouxsie; Girard, Francis; Dennis, Alison; Dziva, Francis; Best, Angus; Phillips, Alan D.; Mousnier, Aurelie; Crepin, Valerie F.; Kruidenier, Laurens; Woodward, Martin J.; Stevens, Mark P.; La Ragione, Roberto M.; MacDonald, Thomas T.; Frankel, Gad; Show all 17 Authors
- Source:
- Infection and immunity 2008 v.76 no.11 pp. 4804-4813
- ISSN:
- 0019-9567
- Subject:
- Citrobacter rodentium; Shigella; T-lymphocytes; actin; animal pathogens; calves; cattle diseases; colon; enterohemorrhagic Escherichia coli; humans; hyperplasia; intestinal mucosa; lambs; luciferase; mice; mixed infection; mutants; phagocytosis; response elements; sequence homology; signal transduction; transcription factor NF-kappa B; transgenes; tumor necrosis factor-alpha; type III secretion system; virulence
- Abstract:
- ... The human pathogen enterohemorrhagic Escherichia coli (EHEC) O157:H7 colonizes human and animal gut via formation of attaching and effacing lesions. EHEC strains use a type III secretion system to translocate a battery of effector proteins into the mammalian host cell, which subvert diverse signal transduction pathways implicated in actin dynamics, phagocytosis, and innate immunity. The genomes of ...
- DOI:
- 10.1128/IAI.00742-08
- http://dx.doi.org/10.1128/IAI.00742-08
- Author:
- Berger, Cedric N., et al. ; Hemrajani, Cordula; Marches, Olivier; Wiles, Siouxsie; Girard, Francis; Dennis, Alison; Dziva, Francis; Best, Angus; Phillips, Alan D.; Mousnier, Aurelie; Crepin, Valerie F.; Kruidenier, Laurens; Woodward, Martin J.; Stevens, Mark P.; La Ragione, Roberto M.; MacDonald, Thomas T.; Frankel, Gad; Show all 17 Authors
- Source:
- Infection and immunity 2008 v.76 no.11 pp. 4804-4813
- ISSN:
- 0019-9567
- Subject:
- luciferase; signal transduction; lambs; phagocytosis; digestive system; enterohemorrhagic Escherichia coli; response elements; mucosa; type III secretion system; actin; Citrobacter rodentium; mixed infection; virulence; pathogens; humans; mice; tumor necrosis factor-alpha; Shigella; calves; hyperplasia; bacterial colonization; transgenes; mutants; sequence homology
- Abstract:
- ... The human pathogen enterohemorrhagic Escherichia coli (EHEC) O157:H7 colonizes human and animal gut via formation of attaching and effacing lesions. EHEC strains use a type III secretion system to translocate a battery of effector proteins into the mammalian host cell, which subvert diverse signal transduction pathways implicated in actin dynamics, phagocytosis, and innate immunity. The genomes of ...