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- Omsland, Anders, et al. Show all 12 Authors
- Infection and immunity 2009 v.77 no.2 pp. 642-656
- Coxiella burnetii; DNA; Q fever; bacterial proteins; endocarditis; evolution; genetic variation; genomics; horizontal gene transfer; human diseases; humans; laboratory animals; niches; pathogens; phenotype; pseudogenes; rodents; transposons; virulence
- ... Genetically distinct isolates of Coxiella burnetii, the cause of human Q fever, display different phenotypes with respect to in vitro infectivity/cytopathology and pathogenicity for laboratory animals. Moreover, correlations between C. burnetii genomic groups and human disease presentation (acute versus chronic) have been described, suggesting that isolates have distinct virulence characteristics. ...