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You searched for: Author "Miller, Melissa" Remove constraint Author: "Miller, Melissa" Journal Insect biochemistry and molecular biology Remove constraint Journal: Insect biochemistry and molecular biology
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1. A novel eukaryotic Na+ methionine selective symporter is essential for mosquito development

Author:
Miller, Melissa M.,   et al.   ; Meleshkevitch, Ella A.; Voronov, Dmitri A.; Penneda, Maria; Fox, Jeffrey M.; Metzler, Ryan; Boudko, Dmitri Y.;     Show all 7 Authors
Source:
Insect biochemistry and molecular biology 2013 v.43 no.8 pp. 755-767
ISSN:
0965-1748
Subject:
Aedes aegypti; Drosophila; RNA interference; absorption; adults; chlorides; complementary DNA; cysteine; ecdysis; ganglia; genome; homocysteine; in situ hybridization; insect larvae; metabolites; methionine; mortality; neurons; sodium; stoichiometry
Abstract:
... AeNAT5 (NCBI, ABZ81822), an orphan member of the insect-specific Nutrient Amino acid Transporter subfamily of SoLute Carrier family 6 (NAT-SLC6) and the first representative of a novel eukaryotic methionine-selective transport system (M), was cloned from cDNA of the vector mosquito, Aedes aegypti. It has orphan orthologs throughout several mosquito genomes, but not in Drosophila or outside Diptera ...
DOI:
10.1016/j.ibmb.2013.05.008
PubMed:
23748165
PubMed Central:
PMC3746589

2. The invertebrate B(0) system transporter, D. melanogaster NAT1, has unique D-amino acid affinity and mediates gut and brain functions

Author:
Miller, Melissa M.,   et al.   ; Popova, Lyudmila B.; Meleshkevitch, Ella A.; Tran, Philip V.; Boudko, Dmitri Y.;     Show all 5 Authors
Source:
Insect biochemistry and molecular biology 2008 v.38 no.10 pp. 923-931
ISSN:
0965-1748
Subject:
transcription factors; Drosophila melanogaster; genes; amino acids; midgut; brain; insect physiology; neurotransmitters; transcription (genetics); molecular cloning; amino acid metabolism
Abstract:
... The CG3252 gene product, DmNAT1, represents the first Nutrient Amino acid Transporter cloned from Drosophila. It absorbs a broader set of neutral amino acids versus earlier characterized insect NATs and mammalian NATs-B(0) system transporters from the Sodium Neurotransmitter symporter Family (SNF, a.k.a. solute carrier family 6, SLC6). In addition to B(0)-specific L-substrates, DmNAT1 equally or m ...
DOI:
10.1016/j.ibmb.2008.07.005
PubMed:
18718864
PubMed Central:
PMC2676678