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- Voisine, Cecile; Mastelic, Beatris; Sponaas, Anne-Marit; Langhorne, Jean
- International journal for parasitology 2010 v.40 no.6 pp. 711-719
- CD4-positive T-lymphocytes; Plasmodium chabaudi; Toll-like receptor 9; dendritic cells; disease control; erythrocytes; immune response; immunopathology; major histocompatibility complex; malaria; mice; parasites
- ... Dendritic cells play an important role in the development of immune responses in malaria, but the contribution of plasmacytoid dendritic cells (pDC) to CD4 T cell activation and immunopathology is unknown. We have investigated pDC in a Plasmodium chabaudi infection in mice. During infection, pDC increased in number and transiently up-regulated expression of Major Histocompatibility Complex class I ...