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- Wu, Jun-Fang; Holmes, Elaine; Xue, Jian; Xiao, Shu-Hua; Singer, Burton H.; Tang, Hui-Ru; Utzinger, Jürg; Wang, Yu-Lan
- International journal for parasitology 2010 v.40 no.6 pp. 695-703
- Necator americanus; Schistosoma japonicum; amino acids; animal models; blood serum; cercariae; citrates; digestive system; glucose; hamsters; hookworms; humans; metabolites; metabolomics; mixed infection; multivariate analysis; nuclear magnetic resonance spectroscopy; parasitoses; succinic acid; tricarboxylic acid cycle; urine; South America
- ... Co-infection with hookworm and schistosomes is a common phenomenon in sub-Saharan Africa, as well as in parts of South America and southeast Asia. As a first step towards understanding the metabolic response of a hookworm-schistosome co-infection in humans, we investigated the metabolic consequences of co-infection in an animal model, using a nuclear magnetic resonance (NMR)-based metabolic profil ...