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- Carranza, Julio César, et al. Show all 11 Authors
- International journal for parasitology 2009 v.39 no.9 pp. 963-973
- Chagas disease; NAD (coenzyme); NADH dehydrogenase; Trypanosoma cruzi; cardiomyopathy; gastrointestinal system; genes; genotype; heart; humans; hybrids; immunogenetics; mutation; parasites; patients; polymerase chain reaction; variance; Argentina; Bolivia; Brazil; Chile
- ... The majority of individuals in the chronic phase of Chagas disease are asymptomatic (indeterminate form, IF). Each year, ~3% of them develop lesions in the heart or gastrointestinal tract. Cardiomyopathy (CCHD) is the most severe manifestation of Chagas disease. The factors that determine the outcome of the infection are unknown, but certainly depend on complex interactions amongst the genetic mak ...
- Cuba, Cesar A. Cuba, et al. Show all 23 Authors
- International journal for parasitology 2010 v.40 no.14 pp. 1599-1607
- Didelphis virginiana; Rhodnius; Triatoma infestans; Trypanosoma cruzi; cardiomyopathy; feces; genes; haplotypes; heart; humans; intergenic DNA; microsatellite repeats; mixed infection; parasites; patients; tissues; Argentina; Brazil; Chile; Colombia; French Guiana; Panama; Paraguay; United States; Venezuela
- ... The intergenic region of spliced-leader (SL-IR) genes from 105 Trypanosoma cruzi I (Tc I) infected biological samples, culture isolates and stocks from 11 endemic countries, from Argentina to the USA were characterised, allowing identification of 76 genotypes with 54 polymorphic sites from 123 aligned sequences. On the basis of the microsatellite motif proposed by to define four haplotypes in Colo ...
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