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- Li, Mao; Leatherland, John F.; Woo, Patrick T.K.
- International journal for parasitology 2013 v.43 no.5 pp. 353-360
- Cryptobia, etc ; Oncorhynchus; antagonists; coasts; coculture; cortisol; culture media; dexamethasone; host-parasite relationships; hosts; parasites; proteins; receptors; salmon; steroids; synthetic glucocorticoids; North America; Show all 17 Subjects
- ... Cryptobia salmositica is a pathogenic haemoflagellate of Pacific salmon, Oncorhynchus spp., on the west coast of North America. The in vitro multiplication of the parasite was significantly enhanced by the addition of cortisol (within a range consistent with physiological levels in salmonid fishes; 10–50ngml−1) to the culture medium (MEM supplemented with FBS). However, higher cortisol concentrati ...
- Li, Mao; Woo, Patrick T.K.
- International journal for parasitology 2014 v.44 no.3-4 pp. 205-210
- Cryptobia, etc ; Salmonidae; agglutination tests; antagonists; antibodies; binding sites; confocal microscopy; cortisol; cytoplasm; dexamethasone; glucocorticoid receptors; host-parasite relationships; in vitro studies; parasites; pathogens; plasma membrane; rabbits; signal transduction; staining; steroid hormone receptors; Show all 20 Subjects
- ... This is the first report to our knowledge that demonstrates a functional steroid hormone receptor in a protozoon. The study used Cryptobia salmositica, a pathogenic haemoflagellate found in salmonid fishes. It has been previously shown that cortisol and dexamethasone (a synthetic glucocorticoid) enhanced the multiplication of C. salmositica under in vitro conditions indicating the presence of gluc ...