Jump to Main Content
- Verplaetse, Emilie, et al. Show all 8 Authors
- International journal for parasitology 2012 v.42 no.4 pp. 401-409
- Trypanosoma brucei; antiserum; bloodstream forms; cell motility; flagellum; fluorescent antibody technique; fractionation; hexokinase; insects; locomotion; metabolites; microbodies; parasites; phosphorylation; polypeptides; recombinant proteins; viability
- ... The majority of the glycolytic enzymes in the African trypanosome are compartmentalised within peroxisome-like organelles, the glycosomes. Polypeptides harbouring peroxisomal targeting sequences (PTS type 1 or 2) are targeted to these organelles. This targeting is essential to parasite viability, as compartmentalisation of glycolytic enzymes prevents unregulated ATP-dependent phosphorylation of in ...