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- Chen, Shuaiyin, et al. Show all 8 Authors
- International journal of antimicrobial agents 2019 v.53 no.2 pp. 109-115
- Shigella; anti-infective agents; antibiotic resistance; antibiotic resistance genes; bacteria; bacteriophages; bioinformatics; gene transfer; horizontal gene transfer; immune system; multiple drug resistance; plasmids; public health; transposons
- ... Multidrug-resistant (MDR) Shigella strains are an enormous threat to public health. Antimicrobial resistance genes are frequently located on plasmids, phages and integrons, which enter bacterial cells by horizontal gene transfer (HGT). CRISPR-Cas systems are adaptive prokaryotic immune systems in bacteria that confer resistance to foreign genetic material such as phages and other mobile genetic el ...