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You searched for: Journal International journal of biological macromolecules Remove constraint Journal: International journal of biological macromolecules Publication Year 2019 Remove constraint Publication Year: 2019 Source 2019 v.140 Remove constraint Source: 2019 v.140
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1. A biocompatible chitosan-ionic liquid hybrid catalyst for regioselective synthesis of 1,2,3-triazols

Author:
Daraie, Mansoureh; Heravi, Majid M.
Source:
International journal of biological macromolecules 2019 v.140 pp. 939-948
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; X-ray diffraction; alkynes; anhydrides; catalysts; catalytic activity; chitosan; copper; energy-dispersive X-ray analysis; folic acid; ionic liquids; leaching; liquids; nanomaterials; nuclear magnetic resonance spectroscopy; organic halogen compounds; polymerization; regioselectivity; scanning electron microscopy; sodium azide; thermogravimetry; triazoles
Abstract:
... A new type of quadruple hybrid system was prepared containing chitosan (CS), folic acid (FA), Poly(styrene-co-maleic anhydride) [SMA] and ionic liquid (IL). This nanocatalyst was synthesized by the functionalization of SMA with folic acid and then polymerization with chitosan in the presence of DCC and NHS. CuI was immobilized onto this support to provide Cu@SMA-FA-CS-IL. The catalyst was fully ch ...
DOI:
10.1016/j.ijbiomac.2019.08.162

2. Agarose native gel electrophoresis of proteins

Author:
Li, Cynthia; Arakawa, Tsutomu
Source:
International journal of biological macromolecules 2019 v.140 pp. 668-671
ISSN:
0141-8130
Subject:
agarose; bovine serum albumin; cattle; chymotrypsin; gel electrophoresis; gels; globulins; lysozyme; virion
Abstract:
... We have developed an agarose-based native gel electrophoresis system that works for both acidic and basic proteins using histidine-MES buffer. This electrophoresis can be done in a flat-bed mode or a vertical mode. While in the flat-bed mode both acidic and basic proteins can be simultaneously analyzed, the vertical gel can only be used for either protein. We have observed that while the migration ...
DOI:
10.1016/j.ijbiomac.2019.08.066

3. Alternagin-C, a disintegrin-like protein from Bothrops alternatus venom, attenuates inflammation and angiogenesis and stimulates collagen deposition of sponge-induced fibrovascular tissue in mice

Author:
Rabelo, Luis Fernando Gonçalves; Ferreira, Bruno Antonio; Deconte, Simone Ramos; Tomiosso, Tatiana Carla; dos Santos, Patty Karina; Andrade, Silvia Passos; Selistre de Araújo, Heloisa Sobreiro; Araújo, Fernanda de Assis
Source:
International journal of biological macromolecules 2019 v.140 pp. 653-660
ISSN:
0141-8130
Subject:
Bothrops; adhesion; angiogenesis; chemokine CCL2; collagen; hemoglobin; inflammation; integrins; mast cells; mice; transforming growth factor beta 1; tumor necrosis factor-alpha; vascular endothelial growth factors; venoms
Abstract:
... Alternagin-C (ALT-C), a disintegrin-like protein obtained from the venom of Bothrops alternatus, is able to modulate cellular behaviors such as adhesion, migration and proliferation, as well as the production of various growth factors via α2β1 integrin, important processes during inflammation, angiogenesis and fibrogenesis, which although appear as distinct events, act concomitantly in several chr ...
DOI:
10.1016/j.ijbiomac.2019.08.171

4. Amidrazone modified acrylic fabric activated with cyanuric chloride: A novel and efficient support for horseradish peroxidase immobilization and phenol removal

Author:
Almulaiky, Yaaser Q.; El-Shishtawy, Reda M.; Aldhahri, Musab; Mohamed, Saleh A.; Afifi, Mohamed; Abdulaal, Wesam H.; Mahyoub, Jazem A.
Source:
International journal of biological macromolecules 2019 v.140 pp. 949-958
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; cyanuric chloride; fabrics; guaiacol; hydrazine; hydrogen peroxide; industrial applications; metal ions; pH; peroxidase; phenol; polyacrylonitrile; scanning electron microscopy; solvents; temperature; wastewater treatment
Abstract:
... In this study, hydrazine treated acrylic fabrics (polyacrylonitrile, PAN) activated with cyanuric chloride was developed as supporting material for horseradish peroxidase (HRP) immobilization. The immobilization of HRP onto the modified supporting material was achieved after being end-over-end incubated for 12 h. Field emission scanning electron microscopy and Fourier-transform infrared spectrosco ...
DOI:
10.1016/j.ijbiomac.2019.08.179

5. Amino acids loaded chitosan/collagen based new membranes stimulate angiogenesis in chorioallantoic membrane assay

Author:
Aleem, Abdur Raheem; Shahzadi, Lubna; Tehseen, Saimoon; Alvi, Farah; Chaudhry, Aqif Anwar; Rehman, Ihtesham ur; Yar, Muhammad
Source:
International journal of biological macromolecules 2019 v.140 pp. 401-406
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; alanine; angiogenesis; arginine; biocompatibility; biodegradation; blood vessels; cell proliferation; chitosan; chorioallantoic membrane; collagen; endothelial cells; freeze drying; hydrogels; phenylalanine; polymers; qualitative analysis; tissue engineering; tissue repair
Abstract:
... Chitosan/collagen-based hydrogels were studied for their promising role in skin tissue engineering applications due to their unique biocompatibility and biodegradation properties. Amino acids are not only the mean of protein building units but also support endothelial cells proliferation and trigger angiogenesis during wound healing. The purpose of this study was to prepare amino acid based pro-an ...
DOI:
10.1016/j.ijbiomac.2019.08.095

6. An optimized aptamer-binding viral tegument protein VP8 inhibits the production of Bovine Herpesvirus-1 through blocking nucleocytoplasmic shuttling

Author:
Xu, Jian; Cai, Yunhong; Jiang, Bo; Li, Xiaoyang; Jin, Huan; Liu, Wenxiao; Kong, Zimeng; Hong, Jiabing; Sealy, Joshua E.; Iqbal, Munir; Li, Yongqing
Source:
International journal of biological macromolecules 2019 v.140 pp. 1226-1238
ISSN:
0141-8130
Subject:
Bovine alphaherpesvirus 1; absorption; antiviral properties; binding capacity; binding sites; cattle; cell membranes; dissociation; herds; infectious bovine rhinotracheitis; oligonucleotides; pathogenicity; pathogens; systematic evolution of ligands by exponential enrichment; virion; viruses
Abstract:
... Bovine herpesvirus 1 (BoHV-1) is a major pathogen of infectious bovine rhinotracheitis in bovine. Previously, we generated the aptamer IBRV A4 using systemic evolution of ligands by exponential enrichment. This aptamer inhibited infectivity of BoHV-1 by blocking viral particle absorption onto cell membranes. In this study, we found that the major tegument protein VP8 of BoHV-1 was involved in inhi ...
DOI:
10.1016/j.ijbiomac.2019.08.165

7. A novel biocompatible core-shell magnetic nanocomposite based on cross-linked chitosan hydrogels for in vitro hyperthermia of cancer therapy

Author:
Eivazzadeh-Keihan, Reza; Radinekiyan, Fateme; Maleki, Ali; Salimi Bani, Milad; Hajizadeh, Zoleikha; Asgharnasl, Somayeh
Source:
International journal of biological macromolecules 2019 v.140 pp. 407-414
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; absorption; aqueous solutions; chitosan; crosslinking; energy-dispersive X-ray analysis; fever; hydrogels; magnetic fields; nanocomposites; nanoparticles; neoplasms; polymers; porosity; scanning electron microscopy; therapeutics; thiourea; transmission electron microscopy
Abstract:
... In this work, the chemical cross-linked interaction between chitosan polymeric chains and synthetic terephthaloyl diisothiocyanate as a cross-linker was accomplished in order to fabricate three dimensional cross-linked chitosan hydrogel. This cross-linked hydrogel with considerable characteristics including high stability and homogeneity in aqueous solution (water) and high porosity was applied as ...
DOI:
10.1016/j.ijbiomac.2019.08.031

8. A novel glycoside hydrolase family 42 enzyme with bifunctional β-galactosidase and α-L-arabinopyranosidase activities and its synergistic effects with cognate glycoside hydrolases in plant polysaccharides degradation

Author:
Lin, Qibin; Wang, Sidi; Wang, Meiling; Cao, Ruoting; Zhang, Ruiqin; Zhan, Ruoting; Wang, Kui
Source:
International journal of biological macromolecules 2019 v.140 pp. 129-139
ISSN:
0141-8130
Subject:
alpha-N-arabinofuranosidase; arabinans; arabinoxylan; beta-galactosidase; calcium; collective action; cooperatives; endo-1,4-beta-xylanase; enzyme activity; glycosides; hydrolysis; lactose; milk; potassium; reducing sugars; sodium; synergism; wheat
Abstract:
... GH42 enzymes are potential candidates for bifunctional β-galactosidase/α-L-arabinopyranosidase. A novel GH42 enzyme (BaBgal42A) from Bacillus was identified, the recombinant BaBgal42A hydrolyzed not only β-D-galactopyranosidic bonds in pNP-β-D-galactopyranoside, oNP-β-D-galactopyranoside, lactose, galactan, and arabinan but also α-L-arabinopyranosidic linkages in pNP-α-L-arabinopyranoside, wheat a ...
DOI:
10.1016/j.ijbiomac.2019.08.037

9. A novel hydrochloride-free chitosan oligosaccharide production method to improve taste

Author:
Kurozumi, Seiji; Kiyose, Masatoshi; Noguchi, Takako; Sato, Kimihiko
Source:
International journal of biological macromolecules 2019 v.140 pp. 109-118
ISSN:
0141-8130
Subject:
acidity; atomization; bitterness; chitosan; enzymatic hydrolysis; ions; manufacturing; molecular weight; oligosaccharides; saltiness; sensory evaluation; spray drying; taste sensitivity
Abstract:
... Chitosan oligosaccharide hydrochloride (COS-HCl) has an unpleasant taste. To improve this taste, we used an enzymatic hydrolysis with chitosan to manufacture hydrochloride-free chitosan oligosaccharide (HFCOS). We found that HFCOS powder with weight-average molecular weight (Mw) of approximately 1000 and a high degree of deacetylation can be obtained from amorphous chitosan in carbonated water by ...
DOI:
10.1016/j.ijbiomac.2019.08.067

10. A novel, kinetically stable copper, zinc superoxide dismutase from Psychropotes longicauda

Author:
Li, Yanan; Zhang, Haibin
Source:
International journal of biological macromolecules 2019 v.140 pp. 998-1005
ISSN:
0141-8130
Subject:
EDTA (chelating agent); Holothuroidea; antioxidant enzymes; biopharmaceuticals; copper; dietary supplements; guanidines; high pressure treatment; hydrolysis; octoxynol; pH; polysorbates; proteinases; sodium chloride; superoxide dismutase; temperature; urea; zinc
Abstract:
... Superoxide dismutases (SODs) are one of the most important antioxidant enzymes against oxidative damage. In the present study, we cloned and expressed a novel and stable Cu, Zn-SOD from a hadal sea cucumber Psychropotes longicauda (i.e., Pl-Cu, Zn-SOD). The purified recombinant enzyme was intracellular, dimeric with the Mr. of approximately 38 kDa, with the expressed activity from 0 °C to 60 °C at ...
DOI:
10.1016/j.ijbiomac.2019.08.089

11. Antibacterial mechanism of Tetrastigma hemsleyanum Diels et Gilg's polysaccharides by metabolomics based on HPLC/MS

Author:
Chen, Xiao; Tao, Lan; Ru, Yi; Weng, Shaohuang; Chen, Zhou; Wang, Jian; Guo, Longhua; Lin, Zhenyu; Pan, Wei; Qiu, Bin
Source:
International journal of biological macromolecules 2019 v.140 pp. 206-215
ISSN:
0141-8130
Subject:
Escherichia coli; Tetrastigma; antibacterial properties; fructose 6-phosphate; gluconeogenesis; glycolysis; herbal medicines; high performance liquid chromatography; medicine; metabolomics; pharmacology; polysaccharides
Abstract:
... Tetrastigma hemsleyanum Diels et Gilg (THDG) is used as a Chinese traditional anti-inflammatory medicine for about thousands of years. In this work, Tetrastigma hemsleyanum Diels et Gilg's polysaccharide (TP) can inhibit E. coli's growth in initial dosing period. Compared with the antibacterial effect of Achyranthe's polysaccharide (AP) from their metabolic profile, it's obviously that their metab ...
DOI:
10.1016/j.ijbiomac.2019.08.097

12. Antioxidant and antibacterial activities of omega-3 rich oils/curcumin nanoemulsions loaded in chitosan and alginate-based microbeads

Author:
Hashim, Ayat F.; Hamed, Said F.; Abdel Hamid, Hoda A.; Abd-Elsalam, Kamel A.; Golonka, Iwona; Musiał, Witold; El-Sherbiny, Ibrahim M.
Source:
International journal of biological macromolecules 2019 v.140 pp. 682-696
ISSN:
0141-8130
Subject:
alginates; antibacterial properties; antioxidant activity; antioxidants; chitosan; crosslinking; curcumin; droplets; drugs; encapsulation; fish; fish oils; linseed; linseed oil; microbeads; nanoemulsions; omega-3 fatty acids; oxidative stability; polymers; therapeutics
Abstract:
... Omega-3 fatty acids can be considered as potential alternative therapeutic agents because of their antimicrobial and antioxidant properties. Two investigated omega-3 rich oils (flaxseed or fish) have been nanoemulsified with and without the natural antioxidant (curcumin, Cur) followed by their incorporation into crosslinked polymeric microbeads. The microbeads were developed from chitosan (CS), al ...
DOI:
10.1016/j.ijbiomac.2019.08.085

13. A polysaccharide isolated from the fruits of Physalis alkekengi L. induces RAW264.7 macrophages activation via TLR2 and TLR4-mediated MAPK and NF-κB signaling pathways

Author:
Yang, Fan; Li, Xiaozhou; Yang, Ye; Ayivi-Tosuh, Selina Mawunyo; Wang, Feihe; Li, Hong; Wang, Guiyun
Source:
International journal of biological macromolecules 2019 v.140 pp. 895-906
ISSN:
0141-8130
Subject:
Physalis alkekengi; Toll-like receptor 2; Toll-like receptor 4; antibodies; bioactive properties; fruits; gene expression regulation; interleukin-6; macrophages; major histocompatibility complex; mitogen-activated protein kinase; nitric oxide; phagocytosis; polysaccharides; signal transduction; transcription factor NF-kappa B; tumor necrosis factor-alpha
Abstract:
... Polysaccharides from Physalis alkekengi L. have been proven to possess many biological activities. In our previous study, a homogeneous polysaccharide (PPSB) was extracted and purified from the fruits of Physalis alkekengi L., and the structure characterization was analyzed. The present study aimed to investigate the effects of PPSB on RAW264.7 macrophage cells activation and the underlying molecu ...
DOI:
10.1016/j.ijbiomac.2019.08.174

14. Application of gum Arabic and maltodextrin for encapsulation of eggplant peel extract as a natural antioxidant and color source

Author:
Sarabandi, Khashayar; Jafari, Seid Mahdi; Mahoonak, Alireza Sadeghi; Mohammadi, Adeleh
Source:
International journal of biological macromolecules 2019 v.140 pp. 59-68
ISSN:
0141-8130
Subject:
2,2-diphenyl-1-picrylhydrazyl; Fourier transform infrared spectroscopy; antioxidant activity; candy; color; eggplants; encapsulation; gum arabic; hydroxyl radicals; maltodextrins; microstructure; particle size; powders; sensory evaluation; spray drying; temperature
Abstract:
... Our aim was to produce an encapsulated powder loaded with eggplant peel extract as a natural source of color and antioxidants through gum Arabic and maltodextrin. The effect of spray drying inlet temperature (140–170°C) and various carriers (maltodextrin, gum Arabic, and their combination) on powder production yield, physical properties, flowability, color, total phenolic content (TPC), antioxidan ...
DOI:
10.1016/j.ijbiomac.2019.08.133

15. Arabic gum-based composite hydrogels reinforced with eucalyptus and pinus residues for controlled phosphorus release

Author:
de Souza, Alana G.; Cesco, Cassiele T.; de Lima, Giovanni F.; Artifon, Samantha E.S.; Rosa, Derval dos S.; Paulino, Alexandre T.
Source:
International journal of biological macromolecules 2019 v.140 pp. 33-42
ISSN:
0141-8130
Subject:
Eucalyptus; Fourier transform infrared spectroscopy; X-ray diffraction; cellulosic fibers; crosslinking; crystal structure; differential scanning calorimetry; free radicals; heat tolerance; hemicellulose; hydrogels; hydrophilicity; lignin; phosphorus; scanning electron microscopy; soil; solutes; thermogravimetry
Abstract:
... Arabic gum-based composite hydrogels reinforced with eucalyptus and pinus residues were synthesized via free-radical reaction aiming to controlled phosphorus release. All hydrogels were characterized by swelling kinetics (SK), Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-Ray diffraction (XRD), thermogravimetric analysis (TGA), differential scanning calorim ...
DOI:
10.1016/j.ijbiomac.2019.08.106

16. Associative behaviour of κ-carrageenan in aqueous solutions and its modification by different monovalent salts as reflected by viscometric parameters

Author:
Bercea, Maria; Wolf, Bernhard A.
Source:
International journal of biological macromolecules 2019 v.140 pp. 661-667
ISSN:
0141-8130
Subject:
DNA; aqueous solutions; carboxymethylcellulose; cations; cooling; kappa carrageenan; models; sodium chloride; viscometry; viscosity
Abstract:
... The viscometric behaviour of κ-carrageenan in aqueous solutions and in the presence of monovalent salts was investigated at 25 °C. Coil, helix or double helix conformations were induced by cooling hot κ-carrageenan solutions under appropriate ionic conditions. A new viscometric approach was used for modeling the behaviour of κ-carrageenan solutions. The intrinsic viscosity, [η], is markedly change ...
DOI:
10.1016/j.ijbiomac.2019.08.144

17. Biocompatible conductive hydrogels based on dextran and aniline trimer as electro-responsive drug delivery system for localized drug release

Author:
Qu, Jin; Liang, Yongping; Shi, Mengting; Guo, Baolin; Gao, Yanzheng; Yin, Zhanhai
Source:
International journal of biological macromolecules 2019 v.140 pp. 255-264
ISSN:
0141-8130
Subject:
aniline; biocompatibility; biodegradability; dextran; drug delivery systems; drugs; electric potential difference; hydrogels; mixing; rheological properties; staining; tissue engineering; toluidine blue
Abstract:
... Dextran with good biocompatibility and degradability shows great potentials for drug delivery and tissue engineering applications. Electro-responsive drug delivery system can provide on-demand and localized drug release. However, dextran-based conductive hydrogel with electrical stimuli responsiveness as drug delivery system has not been reported. Herein, we designed and fabricated a kind of bioco ...
DOI:
10.1016/j.ijbiomac.2019.08.120

18. Biofunctions of antimicrobial peptide-conjugated alginate/hyaluronic acid/collagen wound dressings promote wound healing of a mixed-bacteria-infected wound

Author:
Lin, Zefeng; Wu, Tingting; Wang, Wanshun; Li, Binglin; Wang, Ming; Chen, Lingling; Xia, Hong; Zhang, Tao
Source:
International journal of biological macromolecules 2019 v.140 pp. 330-342
ISSN:
0141-8130
Subject:
Escherichia coli; alginates; angiogenesis; antibiotic resistance; antibiotics; antimicrobial peptides; antimicrobial properties; biodegradability; collagen; drugs; fibroblasts; hyaluronic acid; mechanical properties; methicillin-resistant Staphylococcus aureus; porosity; silver; tissue repair
Abstract:
... The increase in severe infections caused by antibiotic drug resistance and the decrease in the number of new antibacterial drugs approved for use in the last few decades are driving the need for the development of new antimicrobial strategies. Antimicrobial peptides (AMPs) are a potential new class of antimicrobial drugs that are expected to solve the problem of global antibiotic drug resistance. ...
DOI:
10.1016/j.ijbiomac.2019.08.087

19. Cellulose nanocrystals prepared from wheat bran: Characterization and cytotoxicity assessment

Author:
Xiao, Yaqing; Liu, Yingnan; Wang, Xiaojing; Li, Mei; Lei, Hongjie; Xu, Huaide
Source:
International journal of biological macromolecules 2019 v.140 pp. 225-233
ISSN:
0141-8130
Subject:
acid hydrolysis; adsorption; biocompatibility; cellulose; crystal structure; cytotoxicity; heavy metals; manufacturing; nanocomposites; nanocrystals; oils; purification methods; sulfuric acid; temperature; thermal stability; transmission electron microscopy; wheat bran; zeta potential
Abstract:
... Wheat bran is an abundant source of cellulose and is still going to waste because of the lack of knowledge about its further exploitation and comprehensive utilisation. Here, cellulose nanocrystals (CNC) were prepared from wheat bran via sulfuric acid hydrolysis. The effects of hydrolysis time on the morphology, surface charge, yield, structure, thermal stability, physicochemical properties, and c ...
DOI:
10.1016/j.ijbiomac.2019.08.160

20. Characterization of a polysaccharide HP-02 from Honeysuckle flowers and its immunoregulatory and anti-Aeromonas hydrophila effects in Cyprinus carpio L.

Author:
Feng, Junchang; Chang, Xulu; Zhang, Yuru; Lu, Ronghua; Meng, Xiaolin; Song, Dongying; Yan, Xiao; Zhang, Jianxin; Nie, Guoxing
Source:
International journal of biological macromolecules 2019 v.140 pp. 477-483
ISSN:
0141-8130
Subject:
Aeromonas hydrophila; Cyprinus carpio; aquaculture systems; arabinose; blood serum; disease resistance; feed supplements; fish; flowers; galactose; glucose; immunomodulation; immunomodulators; interleukin-10; interleukin-12; interleukin-1beta; interleukin-6; kidney cells; kidneys; mannose; molecular weight; pathogens; phagocytosis; polysaccharides; protein content; rhamnose; secretion; transforming growth factor beta; tumor necrosis factor-alpha; water solubility
Abstract:
... Aquaculture systems are known to be major reservoirs of Aeromonas hydrophila. The use of Chinese medicinal polysaccharides has become a successful strategy to prevent bacterial diseases in aquaculture. A water-soluble polysaccharide, HP-02, was purified from honeysuckle flowers, and the present study was aimed to examine its immunomodulatory and anti-A. hydrophila effects in Cyprinus carpio L. The ...
DOI:
10.1016/j.ijbiomac.2019.08.041