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You searched for: Journal name International journal of biological macromolecules Remove constraint Journal name: International journal of biological macromolecules Publication year rev 7981-2019 Remove constraint Publication year rev: 7981-2019 Source 2019 v.140 Remove constraint Source: 2019 v.140
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1. Alternagin-C, a disintegrin-like protein from Bothrops alternatus venom, attenuates inflammation and angiogenesis and stimulates collagen deposition of sponge-induced fibrovascular tissue in mice

Author:
Luis Fernando Gonçalves Rabelo; Bruno Antonio Ferreira; Simone Ramos Deconte; Tatiana Carla Tomiosso; Patty Karina dos Santos; Silvia Passos Andrade; Heloisa Sobreiro Selistre de Araújo; Fernanda de Assis Araújo
Source:
International journal of biological macromolecules 2019 v.140 pp. 653-660
ISSN:
0141-8130
Subject:
Bothrops; adhesion; angiogenesis; chemokine CCL2; collagen; hemoglobin; inflammation; integrins; mast cells; mice; transforming growth factor beta 1; tumor necrosis factor-alpha; vascular endothelial growth factors; venoms
Abstract:
... Alternagin-C (ALT-C), a disintegrin-like protein obtained from the venom of Bothrops alternatus, is able to modulate cellular behaviors such as adhesion, migration and proliferation, as well as the production of various growth factors via α2β1 integrin, important processes during inflammation, angiogenesis and fibrogenesis, which although appear as distinct events, act concomitantly in several chr ...
DOI:
10.1016/j.ijbiomac.2019.08.171

2. Amino acids loaded chitosan/collagen based new membranes stimulate angiogenesis in chorioallantoic membrane assay

Author:
Abdur Raheem Aleem; Lubna Shahzadi; Saimoon Tehseen; Farah Alvi; Aqif Anwar Chaudhry; Ihtesham ur Rehman; Muhammad Yar
Source:
International journal of biological macromolecules 2019 v.140 pp. 401-406
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; alanine; angiogenesis; arginine; biocompatibility; biodegradation; blood vessels; cell proliferation; chitosan; chorioallantoic membrane; collagen; endothelial cells; freeze drying; hydrogels; phenylalanine; polymers; qualitative analysis; tissue engineering; tissue repair
Abstract:
... Chitosan/collagen-based hydrogels were studied for their promising role in skin tissue engineering applications due to their unique biocompatibility and biodegradation properties. Amino acids are not only the mean of protein building units but also support endothelial cells proliferation and trigger angiogenesis during wound healing. The purpose of this study was to prepare amino acid based pro-an ...
DOI:
10.1016/j.ijbiomac.2019.08.095

3. Antibacterial mechanism of Tetrastigma hemsleyanum Diels et Gilg's polysaccharides by metabolomics based on HPLC/MS

Author:
Xiao Chen; Lan Tao; Yi Ru; Shaohuang Weng; Zhou Chen; Jian Wang; Longhua Guo; Zhenyu Lin; Wei Pan; Bin Qiu
Source:
International journal of biological macromolecules 2019 v.140 pp. 206-215
ISSN:
0141-8130
Subject:
Escherichia coli; Tetrastigma; antibacterial properties; fructose 6-phosphate; gluconeogenesis; glycolysis; herbal medicines; high performance liquid chromatography; medicine; metabolomics; pharmacology; polysaccharides
Abstract:
... Tetrastigma hemsleyanum Diels et Gilg (THDG) is used as a Chinese traditional anti-inflammatory medicine for about thousands of years. In this work, Tetrastigma hemsleyanum Diels et Gilg's polysaccharide (TP) can inhibit E. coli's growth in initial dosing period. Compared with the antibacterial effect of Achyranthe's polysaccharide (AP) from their metabolic profile, it's obviously that their metab ...
DOI:
10.1016/j.ijbiomac.2019.08.097

4. Application of gum Arabic and maltodextrin for encapsulation of eggplant peel extract as a natural antioxidant and color source

Author:
Khashayar Sarabandi; Seid Mahdi Jafari; Alireza Sadeghi Mahoonak; Adeleh Mohammadi
Source:
International journal of biological macromolecules 2019 v.140 pp. 59-68
ISSN:
0141-8130
Subject:
2,2-diphenyl-1-picrylhydrazyl; Fourier transform infrared spectroscopy; antioxidant activity; candy; color; eggplants; encapsulation; gum arabic; hydroxyl radicals; maltodextrins; microstructure; particle size; powders; sensory evaluation; spray drying; temperature
Abstract:
... Our aim was to produce an encapsulated powder loaded with eggplant peel extract as a natural source of color and antioxidants through gum Arabic and maltodextrin. The effect of spray drying inlet temperature (140–170°C) and various carriers (maltodextrin, gum Arabic, and their combination) on powder production yield, physical properties, flowability, color, total phenolic content (TPC), antioxidan ...
DOI:
10.1016/j.ijbiomac.2019.08.133

5. Arabic gum-based composite hydrogels reinforced with eucalyptus and pinus residues for controlled phosphorus release

Author:
Alana G. de Souza; Cassiele T. Cesco; Giovanni F. de Lima; Samantha E.S. Artifon; Derval dos S. Rosa; Alexandre T. Paulino
Source:
International journal of biological macromolecules 2019 v.140 pp. 33-42
ISSN:
0141-8130
Subject:
Eucalyptus; Fourier transform infrared spectroscopy; X-ray diffraction; cellulosic fibers; crosslinking; crystal structure; differential scanning calorimetry; free radicals; heat tolerance; hemicellulose; hydrogels; hydrophilicity; lignin; phosphorus; scanning electron microscopy; soil; solutes; thermogravimetry
Abstract:
... Arabic gum-based composite hydrogels reinforced with eucalyptus and pinus residues were synthesized via free-radical reaction aiming to controlled phosphorus release. All hydrogels were characterized by swelling kinetics (SK), Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-Ray diffraction (XRD), thermogravimetric analysis (TGA), differential scanning calorim ...
DOI:
10.1016/j.ijbiomac.2019.08.106

6. Associative behaviour of κ-carrageenan in aqueous solutions and its modification by different monovalent salts as reflected by viscometric parameters

Author:
Maria Bercea; Bernhard A. Wolf
Source:
International journal of biological macromolecules 2019 v.140 pp. 661-667
ISSN:
0141-8130
Subject:
DNA; aqueous solutions; carboxymethylcellulose; cations; cooling; kappa carrageenan; models; sodium chloride; viscometry; viscosity
Abstract:
... The viscometric behaviour of κ-carrageenan in aqueous solutions and in the presence of monovalent salts was investigated at 25 °C. Coil, helix or double helix conformations were induced by cooling hot κ-carrageenan solutions under appropriate ionic conditions. A new viscometric approach was used for modeling the behaviour of κ-carrageenan solutions. The intrinsic viscosity, [η], is markedly change ...
DOI:
10.1016/j.ijbiomac.2019.08.144

7. Beneficial effect of Sepia esculenta ink polysaccharide on cyclophosphamide-induced immunosuppression and ovarian failure in mice

Author:
Huazhong Liu; Yunbo Zhang; Mingwei Li; Ping Luo
Source:
International journal of biological macromolecules 2019 v.140 pp. 1098-1105
ISSN:
0141-8130
Subject:
Sepia; animal ovaries; antioxidant activity; blood serum; cyclophosphamide; females; immunosuppression; interleukin-2; intraperitoneal injection; malondialdehyde; mice; natural killer cells; oral administration; polysaccharides; population growth; proteins; signal transduction; spleen; squid; superoxide dismutase; thymus gland; tumor necrosis factor-alpha
Abstract:
... In order to investigate prevention of squid ink polysaccharide (SIP) against cyclophosphamide (CP) induced ovarian failure and immunosuppression in mice, female Kunming mice were subjected to intraperitoneal injection of CP (120 mg/kg) and oral administration of SIP (50, 65, 80 and 110 mg/kg, continuous 14 days). At the end of the experiment, animals were sacrificed to collect sera, spleens, thymu ...
DOI:
10.1016/j.ijbiomac.2019.08.200

8. Biocompatible conductive hydrogels based on dextran and aniline trimer as electro-responsive drug delivery system for localized drug release

Author:
Jin Qu; Yongping Liang; Mengting Shi; Baolin Guo; Yanzheng Gao; Zhanhai Yin
Source:
International journal of biological macromolecules 2019 v.140 pp. 255-264
ISSN:
0141-8130
Subject:
aniline; biocompatibility; biodegradability; dextran; drug delivery systems; drugs; electric potential difference; hydrogels; mixing; rheological properties; staining; tissue engineering; toluidine blue
Abstract:
... Dextran with good biocompatibility and degradability shows great potentials for drug delivery and tissue engineering applications. Electro-responsive drug delivery system can provide on-demand and localized drug release. However, dextran-based conductive hydrogel with electrical stimuli responsiveness as drug delivery system has not been reported. Herein, we designed and fabricated a kind of bioco ...
DOI:
10.1016/j.ijbiomac.2019.08.120

9. Boosted selectivity and enhanced capacity of As(V) removal from polluted water by triethylenetetramine activated lignin-based adsorbents

Author:
Chunde Huang; Xiaofeng Shi; Chao Wang; Li Guo; Mengyao Dong; Guosheng Hu; Jing Lin; Tao Ding; Zhanhu Guo
Source:
International journal of biological macromolecules 2019 v.140 pp. 1167-1174
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; adsorbents; adsorption; anions; arsenic; biopolymers; chromium; density functional theory; heavy metals; hydrogen bonding; lignin; metal ions; sorption isotherms; waste liquors; water pollution
Abstract:
... Low-cost natural polymer lignin has been widely used to remove heavy metal ions from polluted water. But it still has some shortcomings, such as poor removal performance, and weak selective adsorption. Thus, in this study, the lignin prepared by Mannich reaction with black liquor was activated with triethylenetetramine (TETA) to achieve a novel adsorbent with high adsorption rates and a strong sel ...
DOI:
10.1016/j.ijbiomac.2019.08.230

10. COX-2/iNOS regulation during experimental hepatic injury and its mitigation by cloudy apple juice

Author:
Devoshree Mukherjee; Riaz Ahmad
Source:
International journal of biological macromolecules 2019 v.140 pp. 1006-1017
ISSN:
0141-8130
Subject:
Kupffer cells; adenosinetriphosphatase; animal injuries; antioxidant activity; antioxidant enzymes; apple juice; collagen; diethylnitrosamine; electron microscopy; etiology; hepatocytes; hepatoprotective effect; high performance liquid chromatography; histopathology; hydroxyproline; inducible nitric oxide synthase; liver; liver function; malondialdehyde; mitochondria; nitrites; oxidation; polyphenols; prostaglandin synthase; rats; transcription factors
Abstract:
... A number of enzymes and transcription factors have been correlated with disease etiology. In this study, involvement of cyclooxygenase-2 and inducible-nitric oxide synthase is examined during diethylnitrosamine (DEN)-induced hepatic injury and cloudy apple juice (CAJ) supplementation. Liver injury was administered in rats by single dose of DEN (10 ml/kg bwt of 1% DEN), while 10 ml/kg bwt CAJ daily ...
DOI:
10.1016/j.ijbiomac.2019.08.180

11. Cellulose nanocrystals prepared from wheat bran: Characterization and cytotoxicity assessment

Author:
Yaqing Xiao; Yingnan Liu; Xiaojing Wang; Mei Li; Hongjie Lei; Huaide Xu
Source:
International journal of biological macromolecules 2019 v.140 pp. 225-233
ISSN:
0141-8130
Subject:
acid hydrolysis; adsorption; biocompatibility; cellulose; crystal structure; cytotoxicity; heavy metals; manufacturing; nanocomposites; nanocrystals; oils; purification methods; sulfuric acid; temperature; thermal stability; transmission electron microscopy; wheat bran; zeta potential
Abstract:
... Wheat bran is an abundant source of cellulose and is still going to waste because of the lack of knowledge about its further exploitation and comprehensive utilisation. Here, cellulose nanocrystals (CNC) were prepared from wheat bran via sulfuric acid hydrolysis. The effects of hydrolysis time on the morphology, surface charge, yield, structure, thermal stability, physicochemical properties, and c ...
DOI:
10.1016/j.ijbiomac.2019.08.160

12. Charges' interaction in polyelectrolyte (nano)complexing of His6-OPH with peptides: Unpredictable results due to imperfect or useless concept?

Author:
Aysel Aslanli; Ilya Lyagin; Elena Efremenko
Source:
International journal of biological macromolecules 2019 v.140 pp. 368-376
ISSN:
0141-8130
Subject:
antibiotic resistance; antimicrobial peptides; antimicrobial properties; aryldialkylphosphatase; computer simulation; electrolytes; enzyme activity; homoserine; lactones; models; nanomaterials; polypeptides; quorum sensing
Abstract:
... Quorum Quenching (QQ) enzymes can be used to prevent bacterial antibiotic resistance by degradation of Quorum Sensing (QS) signaling molecules, for example N-acyl homoserine lactones (AHLs). This paper is aimed at the in silico investigation of the possible combinations of hexahistidine-tagged organophosphorus hydrolase (His6-OPH) with antimicrobial peptides (AMPs) to improve the enzyme activity a ...
DOI:
10.1016/j.ijbiomac.2019.08.137

13. Chitosan-collagen based film for controlled delivery of a combination of short life anesthetics

Author:
Antonio Di Martino; Alexander Drannikov; Natalia S. Surgutskaia; Kadir Ozaltin; Pavel S. Postnikov; Trusova E. Marina; Vladimir Sedlarik
Source:
International journal of biological macromolecules 2019 v.140 pp. 1183-1193
ISSN:
0141-8130
Subject:
benzocaine; biocompatibility; cell proliferation; cytotoxicity; fibroblasts; lidocaine; local anesthetics; metabolites; models; permeability; roughness
Abstract:
... The present research was undertaken to develop a chitosan-collagen film for controlled delivery of combinations of local anesthetics. The film has been prepared by casting which is a versatile, rapid and low-cost approach distinguished by high reproducibility. The mechanical, morphological, and physicochemical properties of the films and the impact of the drug loading were evaluated. We showed tha ...
DOI:
10.1016/j.ijbiomac.2019.08.228

14. Comparison of physicochemical properties of indigenous Ethiopian tuber crop (Coccinia abyssinica) starch with commercially available potato and wheat starches

Author:
Getnet Abera; Belay Woldeyes; Hundessa Dessalegn Demash; Garret M. Miyake
Source:
International journal of biological macromolecules 2019 v.140 pp. 43-48
ISSN:
0141-8130
Subject:
Coccinia; X-ray diffraction; chemical composition; crystal structure; differential scanning calorimetry; gelatinization temperature; pasting properties; physicochemical properties; potato starch; potatoes; scanning electron microscopy; starch; tubers; wheat; wheat starch
Abstract:
... In this study the chemical composition, morphology, crystallinity, thermal, and pasting properties of Anchote (Coccinia abyssinica) starch were compared with commercial potato and wheat starches. Anchote starch showed lower total starch content than that of potato starch. Their morphological properties were investigated using scanning electron microscopy. The mean granule width of potato starch wa ...
DOI:
10.1016/j.ijbiomac.2019.08.118
PubMed:
31419557
PubMed Central:
PMC6941676

15. Complete mitochondrial genome of two Thitarodes species (Lepidoptera, Hepialidae), the host moths of Ophiocordyceps sinensis and phylogenetic implications

Author:
Min Zhang; Zhimei Gao; Jie Yin; Tingting Zhang; Xueyao Zhang; Dongwei Yuan; Tao Li; Yang Zhong; Enbo Ma; Zhumei Ren
Source:
International journal of biological macromolecules 2019 v.140 pp. 794-807
ISSN:
0141-8130
Subject:
Ophiocordyceps sinensis; Oriental traditional medicine; Thitarodes; data collection; genes; hosts; mitochondrial genome; moths; phylogeny; ribosomal RNA; transfer RNA
Abstract:
... Thitarodes (Lepidoptera, Hepialidae) is the only genus that hosts to the Ophiocordyceps sinensis, a traditional Chinese medicine considered as a powerful medicinal supplement. In this study, the complete mitochondrial genomes (mitogenomes) of two species, T. damxungensis and T. pui, have been sequenced, which are 15,928 bp and 15,362 bp in size respectively, and both contain 13 protein-coding gene ...
DOI:
10.1016/j.ijbiomac.2019.08.182

16. Complete mitochondrial genomes of Bittacus strigosus and Panorpa debilis and genomic comparisons of Mecoptera

Author:
Ning Li; Gui-Lin Hu; Bao-Zhen Hua
Source:
International journal of biological macromolecules 2019 v.140 pp. 672-681
ISSN:
0141-8130
Subject:
Bayesian theory; Bittacidae; Boreidae; Nannochoristidae; Panorpa; genes; genetic distance; genetic variation; genomics; insects; mitochondrial genome; phylogeny; statistical analysis; tandem repeat sequences
Abstract:
... Mitochondrial genomes play a significant role in reconstructing phylogenetic relationships and revealing molecular evolution of insects. However, only four mitochondrial genomes were reported in Mecoptera to date. Here, we obtained two new complete mitochondrial genomes of the hangingfly Bittacus strigosus Hagen, 1861 and the scorpionfly Panorpa debilis Westwood, 1846. The results show that the co ...
DOI:
10.1016/j.ijbiomac.2019.08.152

17. Computational design of Bacillus licheniformis RN-01 levansucrase for control of the chain length of levan-type fructooligosaccharides

Author:
Pongsakorn Kanjanatanin; Rath Pichyangkura; Thassanai Sitthiyotha; Thanapon Charoenwongpaiboon; Karan Wangpaiboon; Surasak Chunsrivirot
Source:
International journal of biological macromolecules 2019 v.140 pp. 1239-1248
ISSN:
0141-8130
Subject:
Bacillus licheniformis; Gram-positive bacteria; active sites; antineoplastic agents; carbohydrate binding; food industry; fructooligosaccharides; glucose; hydrogen bonding; levan; levansucrase; molecular dynamics; mutants; pharmaceutical industry; polymerization; polymers; prebiotics
Abstract:
... Levansucrase (LS) from Gram-positive bacteria generally produces a large quantity of levan polymer, a polyfructose with glucose at the end (GFn) but a small quantity of levan-type fructooligosaccharides (LFOs). The properties of levan and LFOs depend on their chain lengths, thereby determining their potential applications in food and pharmaceutical industries such as prebiotics and anti-tumor agen ...
DOI:
10.1016/j.ijbiomac.2019.08.151

18. Crystal structure of bacterial CYP116B5 heme domain: New insights on class VII P450s structural flexibility and peroxygenase activity

Author:
Alberto Ciaramella; Gianluca Catucci; Gianfranco Gilardi; Giovanna Di Nardo
Source:
International journal of biological macromolecules 2019 v.140 pp. 577-587
ISSN:
0141-8130
Subject:
NADP (coenzyme); active sites; biocatalysts; catalytic activity; crystal structure; cytochrome P-450; enzyme activity; enzymes; heme; heme iron; histidine; hydrogen bonding; hydrogen peroxide; ligands; phthalates; polypeptides; protein engineering
Abstract:
... Class VII cytochromes P450 are self-sufficient enzymes carrying a phthalate family oxygenase-like reductase domain and a P450 domain fused in a single polypeptide chain. The biocatalytic applications of CYP116B members are limited by the need of the NADPH cofactor and the lack of crystal structures as a starting point for protein engineering. Nevertheless, we demonstrated that the heme domain of C ...
DOI:
10.1016/j.ijbiomac.2019.08.141

19. Development of active packaging based on chitosan-gelatin blend films functionalized with Chinese hawthorn (Crataegus pinnatifida) fruit extract

Author:
Juan Kan; Jing Liu; Huimin Yong; Yunpeng Liu; Yan Qin; Jun Liu
Source:
International journal of biological macromolecules 2019 v.140 pp. 384-392
ISSN:
0141-8130
Subject:
Crataegus pinnatifida; active food packaging; antioxidant activity; chlorogenic acid; electrostatic interactions; epicatechin; free radical scavengers; fruit extracts; fruits; functional foods; hydrogen bonding; microstructure; permeability; procyanidins; tensile strength; traditional medicine; transmittance; water content; water vapor
Abstract:
... The fruits of Chinese hawthorn (Crataegus pinnatifida) have been used as the functional food and folk medicine due to potent antioxidant activity. In this study, polyphenols were extracted from the fruits of Chinese hawthorn and further added into chitosan-gelatin blend films to develop active packaging. The microstructure, physical, mechanical, barrier and antioxidant properties of the films were ...
DOI:
10.1016/j.ijbiomac.2019.08.155

20. Eco-friendly flame retardant coating deposited on cotton fabrics from bio-based chitosan, phytic acid and divalent metal ions

Author:
Zhihao Zhang; Zhongying Ma; Qian Leng; Yuhua Wang
Source:
International journal of biological macromolecules 2019 v.140 pp. 303-310
ISSN:
0141-8130
Subject:
barium; biobased products; bubbles; burning; calorimetry; chitosan; coatings; combustion; cotton fabric; divalent metals; environmental protection; flame retardants; gases; hardness; heat transfer; metal ions; oxygen; phosphates; phytic acid; scanning electron microscopy; weight gain
Abstract:
... With the increasing awareness of environmental protection, the greening of flame retardants has become an inevitable choice for flame retardant technology. Bio-based materials have the advantages of wide source, recyclability and green environmental protection, and have received extensive attention. In this work, chitosan and phytic acid as intumescent flame retardant system and metal ion as a syn ...
DOI:
10.1016/j.ijbiomac.2019.08.049