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You searched for: Journal name International journal of biological macromolecules Remove constraint Journal name: International journal of biological macromolecules Publication year rev 7984-2016 Remove constraint Publication year rev: 7984-2016 Source 2016 v.89 Remove constraint Source: 2016 v.89
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1. Acetylated starch nanocrystals: Preparation and antitumor drug delivery study

Author:
Huaxi Xiao; Tao Yang; Qinlu Lin; Gao-Qiang Liu; Lin Zhang; Fengxiang Yu; Yuejiao Chen
Source:
International journal of biological macromolecules 2016 v.89 pp. 456-464
ISSN:
0141-8130
Subject:
acetic anhydride; antineoplastic activity; cytotoxicity; doxorubicin; drug delivery systems; fluorescence microscopy; hepatocytes; humans; inhibitory concentration 50; models; nanocrystals; neoplasm cells; rats; rice; starch; uterine cervical neoplasms
Abstract:
... In this study, we developed a new nanoparticulate system for acetylated starch nanocrystals (ASN) using broken rice. ASN with different degrees of substitution (DS) of 0.04, 0.08 and 0.14 were prepared using acetic anhydride as acetylating agent through reaction with starch nanocrystals (SN). The resulting ASN were investigated for the capability to load and release doxorubicin hydrochloride (DOX) ...
DOI:
10.1016/j.ijbiomac.2016.04.037

2. Analysis of thermal pasting profile in corn starch rich in amylose and amylopectin: Physicochemical transformations, part II

Author:
Natalia Rincón-Londoño; Beatriz Millan-Malo; Mario E. Rodríguez-García
Source:
International journal of biological macromolecules 2016 v.89 pp. 43-53
ISSN:
0141-8130
Subject:
retrogradation; corn starch; X-ray diffraction; amylose; cooling; viscosity; amylopectin; gels; differential scanning calorimetry; scanning electron microscopy; pasting properties
Abstract:
... This work focused on the study of the behaviors of the apparent viscosity profiles of isolated corn starches rich in amylose and amylopectin, through the physicochemical and morphological changes that take place during the thermal profile and the gel formation. Frozen dry samples were studied at different stages along the pasting profile. Changes in the structural properties of the samples were st ...
DOI:
10.1016/j.ijbiomac.2016.04.057

3. Anti-diabetic effect of citrus pectin in diabetic rats and potential mechanism via PI3K/Akt signaling pathway

Author:
Yanlong Liu; Man Dong; Ziyu Yang; Siyi Pan
Source:
International journal of biological macromolecules 2016 v.89 pp. 484-488
ISSN:
0141-8130
Subject:
Citrus; adjuvants; animal disease models; blood glucose; blood lipids; fasting; glucose tolerance; glycemic effect; glycogen; insulin resistance; mechanism of action; noninsulin-dependent diabetes mellitus; pectins; rats; signal transduction; tau-protein kinase
Abstract:
... This study was performed to investigate the anti-diabetic effect of citrus pectin in type 2 diabetic rats and its potential mechanism of action. The results showed that fasting blood glucose levels were significantly decreased after 4 weeks of citrus pectin administration. Citrus pectin improved glucose tolerance, hepatic glycogen content and blood lipid levels (TG, TC, LDL-c and HDL-c) in diabeti ...
DOI:
10.1016/j.ijbiomac.2016.05.015

4. Application of bioethanol derived lignin for improving physico-mechanical properties of thermoset biocomposites

Author:
Dilpreet S. Bajwa; Xinnan Wang; Evan Sitz; Tyler Loll; Sujal Bhattacharjee
Source:
International journal of biological macromolecules 2016 v.89 pp. 265-272
ISSN:
0141-8130
Subject:
biocomposites; bioenergy industry; bioethanol; cellulose; corn stover; epoxides; ethanol production; lignin; mechanical properties; pulping; thermal stability; viscosity; wheat straw
Abstract:
... Lignin is the most abundant of renewable polymers next to cellulose with a global annual production of 70million tons, largely produced from pulping and second generation biofuel industries. Low value of industrial lignin makes it an attractive biomaterial for wide range of applications. The study investigated the application of wheat straw and corn stover based lignin derived from ethanol product ...
DOI:
10.1016/j.ijbiomac.2016.04.077

5. BSA/HSA ratio modulates the properties of Ca2+-induced cold gelation scaffolds

Author:
Artur Ribeiro; Vadim Volkov; Mariana B. Oliveira; Jorge Padrão; João F. Mano; Andreia C. Gomes; Artur Cavaco-Paulo
Source:
International journal of biological macromolecules 2016 v.89 pp. 535-544
ISSN:
0141-8130
Subject:
adhesion; bones; bovine serum albumin; cartilage; cell proliferation; cold; fibroblasts; gelation; human serum albumin; hydrophilicity; hydrophobicity; loss modulus; muscles; tissue engineering; viscoelasticity
Abstract:
... An effective tissue engineering approach requires adjustment according to the target tissue to be engineered. The possibility of obtaining a protein-based formulation for the development of multivalent tunable scaffolds that can be adapted for several types of cells and tissues is explored in this work. The incremental substitution of bovine serum albumin (BSA) by human serum albumin (HSA), changi ...
DOI:
10.1016/j.ijbiomac.2016.05.012

6. Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflammation via NOX4 and TLR2 pathways

Author:
Long Yue; Wang Wang; Yan Wang; Ting Du; Weiping Shen; Huiling Tang; Ying Wang; Hongping Yin
Source:
International journal of biological macromolecules 2016 v.89 pp. 376-388
ISSN:
0141-8130
Subject:
Bletilla striata; NAD(P)H oxidase (H2O2-forming); NADP (coenzyme); Toll-like receptor 2; angiotensin II; anti-inflammatory activity; dose response; humans; inflammation; interleukin-6; oxidative stress; polysaccharides; reactive oxygen species; tumor necrosis factor-alpha
Abstract:
... In the current study, we analyzed the functions and mechanisms of Bletilla striata polysaccharide b (BSPb) against Angiotensin II (Ang II)-induced oxidative stress and inflammation in human mesangial cells (HMCs). It was found that BSPb could inhibit generation of Ang II-induced reactive oxygen species (ROS) and activation of proinflammatory cytokines interleukin 6 (IL-6) and tumor necrosis factor ...
DOI:
10.1016/j.ijbiomac.2016.05.002

7. Characterisation of molten globule-like state of sheep serum albumin at physiological pH

Author:
Mohammad Aasif Dar; Wahiduzzaman; Md. Anzarul Haque; Asimul Islam; Md. Imtaiyaz Hassan; Faizan Ahmad
Source:
International journal of biological macromolecules 2016 v.89 pp. 605-613
ISSN:
0141-8130
Subject:
Gibbs free energy; absorption; blood serum; cattle; cysteine; denaturation; emissions factor; fluorescence; humans; kidneys; light scattering; monitoring; pH; serum albumin; sheep; tryptophan; urea
Abstract:
... Sheep serum albumin (SSA) is a 583 amino acid residues long multidomain monomeric protein which is rich in cysteine and low in tryptophan content. The serum albumins (from human, bovine and sheep) play a vital role among all proteins investigated until now, as they are the most copious circulatory proteins. We have purified SSA from sheep kidneys by a simple and efficient two-step purification pro ...
DOI:
10.1016/j.ijbiomac.2016.05.036

8. Characteristics of thermoplastic sugar palm Starch/Agar blend: Thermal, tensile, and physical properties

Author:
R. Jumaidin; S.M. Sapuan; M. Jawaid; M.R. Ishak; J. Sahari
Source:
International journal of biological macromolecules 2016 v.89 pp. 575-581
ISSN:
0141-8130
Subject:
Arenga pinnata; Fourier transform infrared spectroscopy; agar; biodegradability; hydrogen bonding; modulus of elasticity; packaging; scanning electron microscopy; starch; tensile strength; thermal stability; thermoplastics
Abstract:
... The aim of this work is to study the behavior of biodegradable sugar palm starch (SPS) based thermoplastic containing agar in the range of 10–40wt%. The thermoplastics were melt-mixed and then hot pressed at 140°C for 10min. SEM investigation showed good miscibility between SPS and agar. FT-IR analysis confirmed that SPS and agar were compatible and inter-molecular hydrogen bonds existed between t ...
DOI:
10.1016/j.ijbiomac.2016.05.028

9. Characterization of β-glucosidase immobilized on chitosan-multiwalled carbon nanotubes (MWCNTS) and their application on tea extracts for aroma enhancement

Author:
Akile Çelik; Ayşe Dinçer; Tülin Aydemir
Source:
International journal of biological macromolecules 2016 v.89 pp. 406-414
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; beta-glucosidase; carbon nanotubes; chitosan; half life; immobilized enzymes; mixing; odors; pH; scanning electron microscopy; storage quality; tea; temperature
Abstract:
... β-Glucosidase was covalently immobilized on chitosan-MWCNTs carrier and its aroma enhancement effect in different tea samples was investigated. Chitosan-MWCNTs carrier was prepared by mixing chitosan with MWCNTs (5:1w/w) and characterization of prepared composite carrier was done by FTIR, TGA and SEM analysis. β-Glucosidase was covalently immobilized on the composite carrier after glutaraldeyde ac ...
DOI:
10.1016/j.ijbiomac.2016.05.008

10. Chemical properties and antioxidant activity of a water-soluble polysaccharide from Dendrobium officinale

Author:
Qiu-lian Luo; Zhuan-hui Tang; Xue-feng Zhang; Yong-hong Zhong; Su-zhi Yao; Li-sheng Wang; Cui-wu Lin; Xuan Luo
Source:
International journal of biological macromolecules 2016 v.89 pp. 219-227
ISSN:
0141-8130
Subject:
2,2-diphenyl-1-picrylhydrazyl; Dendrobium officinale; anion exchange chromatography; antioxidant activity; arabinose; ethanol; galacturonic acid; glucose; hydroxyl radicals; in vitro studies; mannose; molecular weight; nuclear magnetic resonance spectroscopy; polymerization; polysaccharides; stems
Abstract:
... In this report, a water-soluble polysaccharide was obtained from the dried stems of Dendrobium officinale Kimura et Migo by hot-water (70–75°C) extraction and 85% ethanol precipitation, and successively purification by DEAE-cellulose anion-exchange chromatography and gel-permeation chromatography. The D. officinale polysaccharide (DOP) has a molecular weight of 8500Da. Monosaccharide composition a ...
DOI:
10.1016/j.ijbiomac.2016.04.067

11. Chitosan production by psychrotolerant Rhizopus oryzae in non-sterile open fermentation conditions

Author:
Ozden Canli Tasar; Serkan Erdal; Mesut Taskin
Source:
International journal of biological macromolecules 2016 v.89 pp. 428-433
ISSN:
0141-8130
Subject:
Rhizopus oryzae; agitation; analysis of variance; biomass; carbon; chitosan; experimental design; fermentation; fungi; inoculum; magnesium; magnesium sulfate; microbial contamination; molasses; pH; soil sampling; spores; temperature; Turkey (country)
Abstract:
... A new chitosan producing fungus was locally isolated from soil samples collected around Erzurum, Turkey and identified as Rhizopus oryzae PAS 17 (GenBank accession number KU318422.1). Cultivation in low cost non-sterile conditions was achieved by exploiting its ability to grow at low temperature and pH, thus, undesired microbial contamination could be eliminated when appropriate culture conditions ...
DOI:
10.1016/j.ijbiomac.2016.05.007

12. Cold-set hydrogels made of whey protein nanofibrils with different divalent cations

Author:
Mehdi Mohammadian; Ashkan Madadlou
Source:
International journal of biological macromolecules 2016 v.89 pp. 499-506
ISSN:
0141-8130
Subject:
Fourier transform infrared spectroscopy; atomic force microscopy; calcium chloride; cations; chitosan; coatings; denaturation; gastric juice; gels; heat; hydrocolloids; hydrogen bonding; manganese; manganese chloride; mechanical stress; microstructure; nanofibers; pH; water holding capacity; whey protein
Abstract:
... Whey protein nanofibrils are gaining interest to fabricate cold-set hydrogels due to their ability to gel at lower concentrations than parent proteins. In the present research, fibrillated protein solution was gelled with three different divalent cation salts including CaCl2, MnCl2 and ZnCl2 and the textural and functional characteristics of the resulting hydrogel samples were studied. Atomic forc ...
DOI:
10.1016/j.ijbiomac.2016.05.009

13. Combining prebiotics with probiotic bacteria can enhance bacterial growth and secretion of bacteriocins

Author:
Raminta Pranckutė; Arnoldas Kaunietis; Nomeda Kuisienė; Donaldas J. Čitavičius
Source:
International journal of biological macromolecules 2016 v.89 pp. 669-676
ISSN:
0141-8130
Subject:
Lactobacillus; Lactococcus; antibacterial properties; bacteriocins; food pathogens; human health; microbial growth; oligosaccharides; prebiotics; probiotics; secretion; yogurt
Abstract:
... There is a growing interest in supporting human health by using prebiotics, such as oligosaccharides, and beneficial bacteria, also called probiotics. Combining these two components we can develop synbiotics. In order to create successful combination of synbiotic it is very important to evaluate the influence of prebiotic oligosaccharides to probiotic bacteria and their behavior, such as growth an ...
DOI:
10.1016/j.ijbiomac.2016.05.041

14. Controlled release of drug and better bioavailability using poly(lactic acid-co-glycolic acid) nanoparticles

Author:
Sanjeev K. Pandey; Dinesh K. Patel; Akhilendra K. Maurya; Ravi Thakur; Durga P. Mishra; Manjula Vinayak; Chandana Haldar; Pralay Maiti
Source:
International journal of biological macromolecules 2016 v.89 pp. 99-110
ISSN:
0141-8130
Subject:
DNA damage; apoptosis; atomic force microscopy; bioavailability; breast neoplasms; calorimetry; cell viability; cytotoxicity; emulsifiers; endocytosis; fluorescence; image analysis; lymphoma; nanoparticles; neoplasm cells; polymers; spectroscopy; tamoxifen
Abstract:
... Tamoxifen (Tmx) embedded poly(lactic-co-glycolic acid) (PLGA) nanoparticles (PLGA-Tmx) is prepared to evaluate its better DNA cleavage potential, cytotoxicity using Dalton’s lymphoma ascite (DLA) cells and MDA-MB231 breast cancer cells. PLGA-Tmx nanoparticles are prepared through emulsified nanoprecipitation technique with varying dimension of 17–30nm by changing the concentrations of polymer, emu ...
DOI:
10.1016/j.ijbiomac.2016.04.065

15. Effect of cellulose and lignin on disintegration, antimicrobial and antioxidant properties of PLA active films

Author:
W. Yang; E. Fortunati; F. Dominici; G. Giovanale; A. Mazzaglia; G.M. Balestra; J.M. Kenny; D. Puglia
Source:
International journal of biological macromolecules 2016 v.89 pp. 360-368
ISSN:
0141-8130
Subject:
2,2-diphenyl-1-picrylhydrazyl; Gram-negative bacteria; Xanthomonas arboricola pv. pruni; Xanthomonas vesicatoria; absorption; antioxidant activity; cellulose; composting; food packaging; lignin; microbial growth; nanocomposites; nanocrystals; nanoparticles; plant pathogenic bacteria; polylactic acid
Abstract:
... This study reports the effects on antimicrobial, antioxidant, migration and disintegrability activities of ternary nanocomposite films based on poly(lactic acid) incorporating two biobased nanofillers, (cellulose nanocrystals (CNC) and lignin nanoparticles (LNP)), in two different amounts (1 and 3% wt.). Results from antimicrobial tests revealed a capacity to inhibit the Gram negative bacterial gr ...
DOI:
10.1016/j.ijbiomac.2016.04.068

16. Effect of residual sericin on the structural characteristics and properties of regenerated silk films

Author:
Ji Hye Lee; Dae Woong Song; Young Hwan Park; In Chul Um
Source:
International journal of biological macromolecules 2016 v.89 pp. 273-278
ISSN:
0141-8130
Subject:
biocompatibility; crystal structure; degumming; mechanical properties; sericin; silk; tissue culture
Abstract:
... Regenerated silk film has been increasingly attracting the research community’s attention for biomedical applications due to its good biocompatibility and excellent cyto-compatibility. However, some limitations regarding its mechanical properties, such as brittleness, have restricted the use of silk films for industrial biomedical applications. In this study, regenerated silk films with different ...
DOI:
10.1016/j.ijbiomac.2016.04.073

17. Effects of rutin on the redox reactions of hemoglobin

Author:
Naihao Lu; Yun Ding; Zhen Yang; Pingzhang Gao
Source:
International journal of biological macromolecules 2016 v.89 pp. 175-180
ISSN:
0141-8130
Subject:
circular dichroism spectroscopy; cytotoxicity; heme; hemoglobin; hydrogen peroxide; molecular models; oxidation; oxidative stability; pH; protective effect; quercetin; rutin
Abstract:
... Flavonoids are widely used to attenuate oxidative damage in vitro and in vivo. In this study, we investigated the influence of rutin (quercetin-3-rhamnosylglucoside) on hemoglobin (Hb)- dependent redox reactions, i.e. oxidative stability of Hb and its cytotoxic ferryl intermediate. It was found that rutin induced generation of H2O2, which in turn oxidized Hb rapidly. Meanwhile, rutin exhibited ant ...
DOI:
10.1016/j.ijbiomac.2016.04.066

18. Enhanced adsorption of Cr(VI) from water by guar gum based composite hydrogels

Author:
Jayabrata Maity; Samit Kumar Ray
Source:
International journal of biological macromolecules 2016 v.89 pp. 246-255
ISSN:
0141-8130
Subject:
acrylic acid; adsorption; bentonite; chromium; clay; gels; guar gum; hydrocolloids; ions
Abstract:
... Composite hydrogels were prepared by in situ incorporation of a natural macromolecule guar gum and nano sized bentonite clay in an acrylic network during copolymerization of acrylic acid, N,N-methylenebisacrylamide (MBA) and hydroxyethyl methacrlylate (HEMA) in water. The structure of the hydrogels was characterized and the hydrogels showing the best results in mechanical and swelling properties w ...
DOI:
10.1016/j.ijbiomac.2016.04.036

19. Floating mucoadhesive alginate beads of amoxicillin trihydrate: A facile approach for H. pylori eradication

Author:
Sanjoy Kumar Dey; Pintu Kumar De; Arnab De; Souvik Ojha; Ronita De; Asish Kumar Mukhopadhyay; Amalesh Samanta
Source:
International journal of biological macromolecules 2016 v.89 pp. 622-631
ISSN:
0141-8130
Subject:
Helicobacter pylori; X-radiation; amoxicillin; chitosan; drugs; methylcellulose; models; mucus; polymers; rabbits; scanning electron microscopy; sodium alginate; stomach; sunflower oil
Abstract:
... This study investigates the design of sunflower oil entrapped floating and mucoadhesive beads of amoxicillin trihydrate using sodium alginate and hydroxypropyl methylcellulose as matrix polymers and chitosan as coating polymer to localize the antibiotic at the stomach site against Helicobacter pylori. Beads prepared by ionotropic gellation technique were evaluated for different physicochemical, in ...
DOI:
10.1016/j.ijbiomac.2016.05.027

20. Formulation design, preparation and characterization of multifunctional alginate stabilized nanodroplets

Author:
Fatemeh Baghbani; Fathollah Moztarzadeh; Jamshid Aghazadeh Mohandesi; Fatemeh Yazdian; Manijhe Mokhtari-Dizaji; Sepideh Hamedi
Source:
International journal of biological macromolecules 2016 v.89 pp. 550-558
ISSN:
0141-8130
Subject:
doxorubicin; homogenization; particle size; polymers; surfactants
Abstract:
... In the present study the effect of process (homogenization speed) and formulation (polymer-alginate-concentration, surfactant concentration, drug amount, perfluorohexane volume fraction and co-surfactant inclusion) variables on particle size, entrapment efficiency, and drug release kinetics of doxorubicin-loaded alginate stabilized perfluorohexane nanodroplets were evaluated.Particle size and doxo ...
DOI:
10.1016/j.ijbiomac.2016.05.033