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- Singh, S.K., et al. Show all 3 Authors
- International journal of biological macromolecules 2015 v.72 pp. 131-135
- analgesic effect; animal models; brain; chitosan; clinical trials; drugs; gelation; minocycline; nanoparticles; particle size; people; polysorbates; zeta potential
- ... The purpose of the study is to explore the central anti-nociceptive activity of brain targeted nanoparticles (NP) of minocycline hydrochloride (MH). The NP were formulated using the modified ionotropic gelation method (MHNP) and were coated with Tween 80 (T80) to target them to brain (cMHNP). The formulated nanoparticles have already been characterized for particle size, zeta potential, drug entra ...