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You searched for: Journal name International journal of biological macromolecules Remove constraint Journal name: International journal of biological macromolecules Publication Year 2019 Remove constraint Publication Year: 2019 Subject term antibiotic resistance Remove constraint Subject term: antibiotic resistance Subject term Escherichia coli Remove constraint Subject term: Escherichia coli Text availability Citation in PubAg Remove constraint Text availability: Citation in PubAg
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1. Analysis of DNA protection, interaction and antimicrobial activity of isatin derivatives

Author:
Mohamed Abdulhamid Ganim; Mehmet Cengiz Baloglu; Aysenur Aygun; Yasemin Celik Altunoglu; Hakan Sezgin Sayiner; Fatma Kandemirli; Fatih Sen
Source:
International journal of biological macromolecules 2019 v.122 pp. 1271-1278
ISSN:
0141-8130
Subject:
Escherichia coli; Gram-positive bacteria; antibacterial properties; antibiotic resistance; calves; in vitro studies; methicillin; methicillin-resistant Staphylococcus aureus; moieties; plasmids; thymus gland
Abstract:
... Isatin, thiosemicarbazone and their derivatives have been widely used in biological applications such as antimicrobial, antiviral and anticancer therapies. Herein, eight isatin and thiosemicarbazone derivative compounds were re-synthesized and evaluated for DNA binding analysis including DNA protection studies using plasmid DNA (pUC19) and DNA interaction experiments using calf thymus DNA (CT-DNA) ...
DOI:
10.1016/j.ijbiomac.2018.09.084

2. Biofunctions of antimicrobial peptide-conjugated alginate/hyaluronic acid/collagen wound dressings promote wound healing of a mixed-bacteria-infected wound

Author:
Zefeng Lin; Tingting Wu; Wanshun Wang; Binglin Li; Ming Wang; Lingling Chen; Hong Xia; Tao Zhang
Source:
International journal of biological macromolecules 2019 v.140 pp. 330-342
ISSN:
0141-8130
Subject:
Escherichia coli; alginates; angiogenesis; antibiotic resistance; antibiotics; antimicrobial peptides; antimicrobial properties; biodegradability; collagen; drugs; fibroblasts; hyaluronic acid; mechanical properties; methicillin-resistant Staphylococcus aureus; porosity; silver; tissue repair
Abstract:
... The increase in severe infections caused by antibiotic drug resistance and the decrease in the number of new antibacterial drugs approved for use in the last few decades are driving the need for the development of new antimicrobial strategies. Antimicrobial peptides (AMPs) are a potential new class of antimicrobial drugs that are expected to solve the problem of global antibiotic drug resistance. ...
DOI:
10.1016/j.ijbiomac.2019.08.087

3. Enhanced antibacterial activity of Egyptian local insects' chitosan-based nanoparticles loaded with ciprofloxacin-HCl

Author:
Narguess Marei; Ahmed H.M. Elwahy; Taher A. Salah; Youssef El Sherif; Emtithal Abd El-Samie
Source:
International journal of biological macromolecules 2019 v.126 pp. 262-272
ISSN:
0141-8130
Subject:
Bacillus thuringiensis; Coleoptera; Escherichia coli; Pseudomonas aeruginosa; antibacterial properties; antibiotic resistance; bioavailability; biodegradability; chitosan; ciprofloxacin; crosslinking; drug delivery systems; drugs; honey bees; hydrogels; methicillin; methicillin-resistant Staphylococcus aureus; minimum inhibitory concentration; nanoparticles; particle size distribution; polymers; shrimp shells; zeta potential
Abstract:
... Chitosan (CS), possess enormous properties, being biodegradable, biocompatible, and antimicrobial. CS could be formulated and casted into different forms including 2D films, hydrogels, and nanoparticles. Chitosan-based nanoparticles (CSNPs) showed countless interest as polymeric drug delivery system (DDS) with its improved bioavailability, and stability when compared with traditional DDS. Ciproflo ...
DOI:
10.1016/j.ijbiomac.2018.12.204

4. Silver nanoparticles in situ synthesized by polysaccharides from Sanghuangporus sanghuang and composites with chitosan to prepare scaffolds for the regeneration of infected full-thickness skin defects

Author:
Luoxiao Ran; Yini Zou; Junwen Cheng; Fei Lu
Source:
International journal of biological macromolecules 2019 v.125 pp. 392-403
ISSN:
0141-8130
Subject:
Escherichia coli; Staphylococcus aureus; animal injuries; antibiotic resistance; chitosan; freeze drying; nanoparticles; nanosilver; reducing agents; silver; toxicity
Abstract:
... In recent years, silver nanoparticles have widely been used in antibacterial dressings to solve antibiotic resistance problems. However, traditional methods for reducing silver nanoparticles are usually toxic. To overcome this problem, Sanghuangporus sanghuang polysaccharides (FSHPs) were used as a green reducing agent to prepare silver nanoparticles (AgNPs) with a size of 3–35 nm. The FSHPs‑silve ...
DOI:
10.1016/j.ijbiomac.2018.12.052