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- Author:
- Burbano, Rommel R., et al. ; Ferreira-Fernandes, Hygor; Barros, Marcos Aurélio L.; Souza Filho, Manoel D.; Medeiros, Jand Venes R.; Vasconcelos, Daniel Fernando P.; Silva, Durcilene A.; Leódido, Ana Carolina M.; Silva, Felipe Rodolfo P.; França, Luiz Felipe C.; Di Lenardo, David; Yoshioka, France Keiko N.; Rey, Juan Antonio; Pinto, Giovanny R.; Show all 14 Authors
- Source:
- International journal of biological macromolecules 2019 v.128 pp. 934-940
- ISSN:
- 0141-8130
- Subject:
- Anacardium occidentale; anti-inflammatory activity; cashew gum; chlorhexidine; gels; gene overexpression; genes; gingiva; inflammation; interferon-gamma; interleukin-10; interleukin-4; models; periodontitis; rats; topical application; transcription (genetics); transforming growth factor beta 1
- Abstract:
- ... This study aimed to explore the effect of topically administering an orabase gel containing cashew gum (CG), a complex polysaccharide from Anacardium occidentale L., on the transcription of important proinflammatory (COX-2, NOS-2, INF-γ, OSCAR, and MYD88) and anti-inflammatory genes (IL-10, IL-4, and TGFβ1) in the gingival tissues of rats with ligature-induced periodontitis, compared to the effect ...
- DOI:
- 10.1016/j.ijbiomac.2019.02.002
-
https://dx.doi.org/10.1016/j.ijbiomac.2019.02.002