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You searched for: Journal Journal of Asian natural products research Remove constraint Journal: Journal of Asian natural products research Publication Year 2018 Remove constraint Publication Year: 2018 Source 2018 v.20 no.2 Remove constraint Source: 2018 v.20 no.2 Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. A new triterpene ester and other chemical constituents from the aerial parts of Anodendron paniculatum and their cytotoxic activity

Author:
Viet Ho, Duc; Thi Hoang, Hanh Nhu; Quoc Vo, Hung; Minh Nguyen, Hien; Raal, Ain; Thi Nguyen, Hoai
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 188-194
ISSN:
1477-2213
Subject:
Anodendron; aerial parts; chemical composition; cytotoxicity; human cell lines; humans; inhibitory concentration 50; neoplasm cells; phthalates; stigmasterol; ursolic acid
Abstract:
... The aim of the research was to study the active constituents of Anodendron paniculatum Roxb. (Apocynaceae). A new triterpene ester, named anopaniester (1), and cycloartenol (2), ursolic acid (3), esculenic acid (4), bis-(2-ethylhexyl) phthalate (5), desmosterol (6), stigmasterol (7), vaniline (8), and (E)-phytol (9), were isolated from the aerial parts of A. paniculatum. Compounds 3 and 6 showed t ...
DOI:
10.1080/10286020.2017.1336163

2. Anti-neuroinflammatory diterpenoids from the endangered conifer Podocarpus imbricatus

Author:
Hu, Chang-Ling; Xiong, Juan; Xiao, Chen-Xi; Tang, Yu; Ma, Guang-Lei; Wan, Jiang; Hu, Jin-Feng
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 101-108
ISSN:
1477-2213
Subject:
Dacrycarpus imbricatus; branches; conifers; diterpenoids; gardens; inhibitory concentration 50; lipopolysaccharides; mice; neuroglia; nitric oxide; spectroscopy
Abstract:
... Ten diterpenoids including three new abietanes (1–3) were isolated from the twigs and needles of Podocarpus imbricatus, an endangered conifer growing in a Cantonese garden. The new structures were established by means of spectroscopic methods. Among the isolates, 3β-hydroxy-abieta-8,11,13-trien-7-one (5), decandrin G (6), and 7,15-pimaradien-18-oic acid (8) showed significant anti-neuroinflammator ...
DOI:
10.1080/10286020.2017.1319821

3. Continuous synthesis and anti-myocardial injury of tanshinone IIA derivatives

Author:
Qin, Yin-Lin; Chen, Lei; He, Wei; Su, Mei; Jin, Qiu; Fang, Zheng; Ouyang, Ping-Kai; Guo, Kai
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 139-147
ISSN:
1477-2213
Subject:
cardioprotective effect; chemical derivatives; chlorination; quinones; synthesis
Abstract:
... A series of tanshinone IIA derivatives were synthesized through sulfonation, slat-forming, chlorination, and amidation reactions. Meanwhile, anti-myocardial injury activity was evaluated in vitro. D8 and D9 exhibited a slightly higher anti-myocardial injury (5.78, 7.46 μM) activity compared with esmolol (8.12 μM). In addition, they also displayed a concentration-dependent inhibition on the anti-my ...
DOI:
10.1080/10286020.2017.1337751

4. Cytotoxic triterpenes from the acid hydrolyzate of Gynostemma pentaphyllum saponins

Author:
Shi, Lin; Tan, De-Hong; Yan, Ting-Cai; Jiang, Dong-Hua; Hou, Ming-Xiao
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 182-187
ISSN:
1477-2213
Subject:
Gynostemma pentaphyllum; cytotoxicity; human cell lines; humans; hydrolysates; neoplasm cells; nuclear magnetic resonance spectroscopy; saponins; spectral analysis; triterpenoids
Abstract:
... One new dammarane-type triterpene, gypsapogenin A (1), was isolated from the acid hydrolyzate of total saponins from Gynostemma pentaphyllum (Thunb.) Makino, together with two known compounds, (20S,24S)-3β,20,21β,23β,25-pentahydroxy-21,24-cyclodammarane (2) and (23S)-3β-hydroxydammar-20,24-dien-21-oic acid 21,23-lactone (3). Its structural elucidations were accomplished mainly on the basis of the ...
DOI:
10.1080/10286020.2017.1322070

5. Evaluation of berberine as a natural fungicide: biodegradation and antimicrobial mechanism

Author:
Li, Ying; Yin, Yi-Ming; Wang, Xin-Yue; Wu, Hao; Ge, Xi-Zhen
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 148-162
ISSN:
1477-2213
Subject:
Oriental traditional medicine; berberine; biodegradation; biopesticides; fungi; fungicides; glucans; soil; soil bacteria
Abstract:
... Berberine (BBR) is a traditional Chinese medicine which recently was applied as a biological pesticide. Here, we studied the antimicrobial mode of BBR and its impact on soil bacterial diversity. BBR was more effective against fungi than bacteria due to the specific interaction between BBR and glucan. Also, BBR was degraded rapidly in soil, leading to the limited effect on soil bacterial diversity. ...
DOI:
10.1080/10286020.2017.1329300

6. Secreted frizzled-related protein 1 (SFRP1) gene methylation changes in the human lung adenocarcinoma cells treated with L-securinine

Author:
Yang, Xi; Han, Shu-Wen; Liu, Hui; Zhu, Ling; Chen, Yu-Xin; Ji, Zhao-Ning
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 163-171
ISSN:
1477-2213
Subject:
DNA methylation; biomarkers; bisulfites; cytotoxicity; death; gene expression; genes; humans; lung neoplasms; lungs; neoplasm cells; prognosis; promoter regions; proteins; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; sequence analysis
Abstract:
... Lung cancer remains the leading cause of cancer-related death worldwide. It is important to explore the biomarkers of diagnosis and prognosis in lung cancer. To evaluate the cytotoxicity of L-securinine and the expression and methylation of secreted frizzled-related proteins (SFRPs) genes in the human lung adenocarcinoma cells, cell counting kit-8 (CCK-8) assay was used to assess the proliferation ...
DOI:
10.1080/10286020.2017.1329828

7. Selective dual cholinesterase inhibitors from Aconitum laeve

Author:
Ahmad, Hanif; Ahmad, Shujaat; Shah, Syed Adnan Ali; Khan, Hidayat Ullah; Khan, Farman Ali; Ali, Mumtaz; Latif, Abdul; Shaheen, Farzana; Ahmad, Manzoor
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 172-181
ISSN:
1477-2213
Subject:
Aconitum; acetylcholinesterase; benzene derivatives; cholinesterase inhibitors; diterpenoid alkaloids; inhibitory concentration 50; roots; spectroscopy
Abstract:
... New lycoctonine-type dual cholinesterase inhibitor, swatinine-C (1), along with three known norditerpenoid alkaloids, hohenackerine (2), aconorine (5) and lappaconitine (6) and two synthetically known but phytochemically new benzene derivatives, methyl 2-acetamidobenzoate (3) and methyl 4-[2-(methoxycarbonyl)anilino]-4-oxobutanoate (4), was isolated from the roots of A. laeve. Structures of new an ...
DOI:
10.1080/10286020.2017.1319820

8. Synthesis and structure-activity relationship of theasapogenol galactosides against Magnaporthe oryzae

Author:
Huo, Guang-Hua; Chen, Xu-Tao; Li, Zhi-Min; Liu, Cheng-Fu; Xiao, Da-Jin
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 128-138
ISSN:
1477-2213
Subject:
Camellia oleifera; Magnaporthe oryzae; Schima superba; galactose; galactosides; glycosylation; moieties; mycelium; regioselectivity; saponins; structure-activity relationships; water solubility
Abstract:
... Camellia oleifera is expected to provide alternative aglycone to synthesize some saponins similar to that from Schima superba with inhibitory activity against Magnaporthe oryzae. Eight theasapogenol galactosides were synthesized via protection of adjacent hydroxyl groups by a benzylidene for regioselective glycosylation in the multi-hydroxyl sapogenin. Water soluble galactose chain connected far f ...
DOI:
10.1080/10286020.2017.1325877

9. Two new 2-(2-Hydroxy-2-phenylethyl)chromens from agarwood originating from Aquilaria crassna

Author:
Wang, Hong-Ni; Mei, Wen-Li; Dong, Wen-Hua; Kong, Fan-Dong; Li, Wei; Yuan, Jing-Zhe; Dai, Hao-Fu
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 122-127
ISSN:
1477-2213
Subject:
Aquilaria crassna; Ralstonia solanacearum; acetylcholinesterase; antibacterial properties; nuclear magnetic resonance spectroscopy
Abstract:
... Two new 2-(2-hydroxy-2-phenylethyl)chromones (1‒2), along with three known 2-(2-phenylethyl)chromones (3‒5), were isolated from the agarwood originating from Aquilaria crassna Pierre ex Lecomte. Their structures were determined by the spectroscopic methods including 1D and 2D NMR analysis and comparison with reported data in the literature. All the compounds were isolated from agarwood of A. crass ...
DOI:
10.1080/10286020.2017.1379998

10. Two new p-coumaroylated sesquiterpenoids from Pilea cavaleriei

Author:
Ren, Heng-Chun; Zhang, Jun; Liang, Hong
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 109-116
ISSN:
1477-2213
Subject:
Pilea; ethanol; herbs; nuclear magnetic resonance spectroscopy; sesquiterpenoids
Abstract:
... A new p-coumaroylated santalane-type sesquiterpenoid, 8-p-coumaroyl-α-santalene (1), a new p-coumaroylated oplopanane-type sesquiterpenoid, 8-β-p-coumaroyl-oplopanone (2), and three known p-coumaroylated humulene-type sesquiterpenoids (3–5) were isolated from the ethanol extract of the whole herbs of Pilea cavaleriei. Their structures were elucidated based on the combination of 1D and 2D NMR and H ...
DOI:
10.1080/10286020.2017.1320990

11. Two new prenylflavonoids from Morus alba

Author:
Gao, Li; Li, Yuan-Dong; Zhu, Bao-Kun; Li, Zhi-Yu; Huang, Li-Bin; Li, Xian-Yi; Wang, Fei; Ren, Fu-Cai; Liao, Tou-Gen
Source:
Journal of Asian natural products research 2018 v.20 no.2 pp. 117-121
ISSN:
1477-2213
Subject:
Morus alba; branches; leaves; spectral analysis
Abstract:
... Two new prenylflavonoids, morusalbols A and B (1 and 2), were isolated from the branches and leaves of Morus alba, together with three known compounds, kuwanon C (3), morusin (4), morusinol (5). The structures of these two prenylflavonoids were elucidated by extensive analyzes of the spectroscopic data. ...
DOI:
10.1080/10286020.2017.1343303