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- Hanff, Erik, et al. Show all 4 Authors
- Journal of Chromatography B 2014 v.970 pp. 44-52
- acetylcysteine; blood; formates; gas chromatography-mass spectrometry; glutathione; high performance liquid chromatography; humans; hydrochloric acid; ionization; monitoring; nitrites; nitroprusside; pH; quantitative analysis; saliva; stable isotopes; ultrafiltration; urine
- ... A specific, sensitive and fast LC–MS/MS method with positive electrospray ionization for the quantitative determination of nitrite in human plasma is reported. Added [15N]nitrite served as the internal standard (IS). Endogenous nitrite and IS were converted to their S-nitrosoglutathione (GSNO) derivatives, i.e., GS14NO and GS15NO, respectively, by using excess glutathione (GSH) and HCl. For plasma ...