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- Dias, Camila C.; Moraes, Mauro P.; Weiss, Marcelo; Diaz-San Segundo, Fayna; Perez-Martin, Eva; Salazar, Andres M.; de los Santos, Teresa; Grubman, Marvin J.
- Journal of Interferon and Cytokine Research 2012 v.32 no.10 pp. 462
- Foot-and-mouth disease virus; animal diseases; cell culture; disease control; double-stranded RNA; foot-and-mouth disease; gene expression; gene induction; genes; immunity; interferon-alpha; mononuclear leukocytes; oligonucleotides; swine; therapeutics; vaccines
- ... Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals. Vaccines require approximately 7 days to induce protection, thus prior to this time vaccinated animals are still susceptible to the disease. Our group has previously shown that swine inoculated with 1x10^11 focus forming units (FFU) of a replication-defective human adenovirus containing the gene for po ...